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Bionase 5K Injection contains L-asparaginase. It is used to treat Acute Lymphoblastic Leukemia (cancer of white blood cells) in patients aged four months and above. In Acute Lymphoblastic Leukemia, the white blood cells called lymphocytes multiply in an uncontrolled and abnormal manner. This disorder is also known as Acute Lymphocytic Leukemia.

This medicine should not be used if you have severe problems with your pancreas or allergic to any of the ingredients of this medicine. Talk to your physician if you are a diabetic patient as this medicine contains glucose. The common side effects of Bionase 5K Injection are muscle pain, nausea, infections, abdominal pain, and diarrhea.

Use effective birth control during the treatment with Bionase 5K Injection and for at least three months after the last dose. Women should use contraception methods other than oral contraceptives.

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Acute Lymphoblastic Leukemia (ALL)

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Cancer cells need a substance called asparagine to survive. Bionase 5K Injection works by lowering the levels of asparagine in the body.

"}},{"id":"d2b20346-df70-4327-ad70-fbf9992b6612","type":"PARA","position":4,"content_placement":1,"data":{"heading":"Interaction of Bionase 5K Injection with other drugs","text":"

Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products that you are taking or have taken before the treatment. Certain medications may interact with Bionase 5K injection and can cause undesirable side effects.

"}},{"id":"0ef32cb5-8198-4997-be22-d3d7837d3137","type":"PARA","position":5,"content_placement":1,"data":{"heading":"More Information about Bionase 5K Injection","text":"

Keep Bionase 5K Injection out of sight and reach of children.
Store in a refrigerator (2°C to 8°C).

"}},{"id":"db6be46e-586e-4dc3-aa4d-5efe84a79500","type":"PARA","position":6,"content_placement":1,"data":{"heading":"How to consume Bionase 5K Injection","text":"

It will be given to you by your health care professional. Do not self-administer. Your physician will decide the dose and duration of your treatment based on the disease severity and other factors.

"}},{"id":"c34f5036-0f3c-4b56-a186-7a6e010c772f","type":"SAFETY_ADVICE","position":7,"content_placement":2,"data":{"heading":"Safety Advice for Bionase 5K Injection","safety_list":[{"id":"ae803b7c-ef5d-4c8f-b98b-751438661d39","advice":"Breast Feeding","tag":"unsafe","description":"

You must not breastfeed your baby during treatment with Bionase 5K Injection. You need to tell your physician if you are breastfeeding before taking this medicine.

","imageUrl":"https://assets.mrmed.in/others/file-1674132409667-45039420-Breatfeeding.jpg"},{"id":"20aaab15-eeed-428d-bf2e-bf70f71fec0f","advice":"Alcohol","tag":"Consult your doctor","description":"

It is not known whether it is safe to consume alcohol with Bionase 5K Injection. Please consult your doctor.

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You must tell your physician if you have any liver disorders before taking Bionase 5K Injection.

","imageUrl":"https://assets.mrmed.in/others/file-1674132424807-417765861-Liver.jpg"},{"id":"f4abb50a-5bdb-40b2-806c-5aedf5dac5a1","advice":"Lungs","tag":"Consult your doctor","description":"

You need to tell your physician if you have any lung disorders before taking Bionase 5K Injection.

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Bionase 5K Injection can cause dizziness and drowsiness. Avoid driving if you are unwell.

","imageUrl":"https://assets.mrmed.in/others/file-1674132431331-421990512-Driving.jpg"},{"id":"b8deed95-95ef-497b-a96b-0f08fa744562","advice":"Pregnancy","tag":"Consult your doctor","description":"

You need to tell your physician if you are pregnant or planning to get pregnant before taking Bionase 5K Injection. it will be given to you if clearly needed.

","imageUrl":"https://assets.mrmed.in/others/file-1674132401469-949914510-Pregnancy.jpg"}]}},{"id":"6fe98b37-cf94-4439-8756-decfaa6c23db","type":"PARA","position":8,"content_placement":1,"data":{"heading":"Side Effects of Bionase 5K Injection","text":"

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.

Serious

Severe allergic reactions
High blood sugar levels
Bleeding
Liver and nervous problems
Pain near your stomach (inflammation of the pancreas)
Blood clots in arm or leg
Pain, bruising, swelling, or hardening of the skin at the injection site

Common

Nausea
Muscle pain
Weight loss
Infections (fever, rapid heart rate, confusion, or a rash)
Difficulty breathing
Inflammation of the digestive tract
Diarrhea
Abdominal pain, discomfort
Headache
Tiredness

"}},{"id":"afae51dd-3d70-4447-b801-f4dd40eaa848","type":"PARA","position":9,"content_placement":1,"data":{"heading":"Word of Advice","text":"

This injection should be administered only by the doctor or nurse. Inform the doctor if the patient has any allergic response, blood pressure, kidney or liver problems, and medication taken for different medical conditions. Consult the doctor if the patient is pregnant or breastfeeding mother before taking this medication. Avoid driving while taking this medication, as it can cause dizziness. Avoid handling heavy machinery as the patient may lack concentration.

"}},{"id":"6f96560a-9fe1-47e0-a1cd-198c2d7cdcf7","type":"FAQ","position":10,"content_placement":2,"data":{"heading":"FAQs about Bionase 5K Injection","faq_list":[{"id":"ef922456-f265-4dee-9228-ee1623e16ce8","question":"

Can Bionase 5K Injection affect blood glucose levels?

","answer":"

Yes, this medication can increase blood glucose levels as it contains glucose. Blood glucose levels should be monitored regularly while taking this medication.

"},{"id":"6391cd81-f96c-4988-a7bd-40a99170da90","question":"

Can Bionase 5K Injection be self-administered?

","answer":"

No, this injection should be administered only by the doctor or nurse and not self-administered. Wrong injection techniques can lead to complications.

"},{"id":"ffeea56d-6863-40f7-b844-9aa90e8dea7b","question":"

Can I use Bionase 5K Injection while driving?

","answer":"

Avoid driving and handling heavy machinery while taking this medication, as it causes dizziness and lack of concentration.

"},{"id":"a435b24a-1169-4f4d-83d3-df5ead3ffce9","question":"

Is it safe to use Bionase 5K Injection during breastfeeding?

","answer":"

It is unsafe to use this medication during breastfeeding, and inform the doctor before taking this medication.

"},{"id":"c26c37f0-ebd2-488f-aeb5-817f597ef643","question":"

Is Bionase 5K Injection a chemotherapy medication?

","answer":"

Yes, Bionase 5K Injection is a chemotherapy medicine that is used to treat Acute Lymphoblastic Leukemia (cancer of white blood cells).

"}]}},{"id":"263a16f0-6b84-4fb9-b537-ba9cc8e78584","type":"PARA","position":11,"content_placement":3,"data":{"heading":"Fact Box of Bionase 5K Injection","text":"

Molecule name: L-Asparaginase	Pharmacological class: Enzyme
Therapeutic class: Antitumor agent	Indications: Acute Lymphoblastic Leukemia (ALL)

"}},{"id":"bc8278f3-7015-44b8-a839-bea1a80a1423","type":"PARA","position":12,"content_placement":3,"data":{"heading":"References","text":"

Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Cytotoxic agents, 12th edition, 2011, 1720.
KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 869.
Porton Biopharma Limited, Electronic medicines compendium (emc), [Revised on June 2021] [ Accessed on 9th August 2021], https://www.medicines.org.uk/emc/files/pil.12340.pdf
Merck & Co., Inc., US Food and Drug Administration, [Issued on 2000] [ Accessed on 5th August 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2002/aspamer080102LB.pdf

"}},{"id":"c57c4faa-e0c2-449d-9254-b1a1b13d9140","type":"DISCLAIMER","position":13,"content_placement":5,"data":{"heading":"Disclaimer","text":"

MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.

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