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Bryxta 200mg Injection

Prescription Required
Cold Chain Required
bevacizumab

₹7571

MRP: ₹9995

(You Save ₹2424)

1 VIAL(s)

24% OFF
Bryxta 200mg Injection
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₹7571

MRP: ₹9,995.00

Inclusive of all taxes

24% Off

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1 Vial(s)

1 Vial(s)

₹ 7571.0/Unit
Prescription Required
Prescription Required
Cold Chain Required
Cold Chain
Info

Salt Composition

BEVACIZUMAB

Marketer

ZYDUS CADILA

Prepaid Only. Non-Returnable.

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Introduction

Bryxta 200mg Injection contains bevacizumab, a targeted bevaneal cancer medicine that helps prevent tumour growth by blocking the formation of new blood vessels that supply cancer cells. Among the key bevaneal 400 uses, it is prescribed along with other chemotherapy medicines for cancers such as metastatic breast cancer, brain cancer, cervical cancer, kidney cancer, lung cancer, and colorectal cancer. It is also used in cancers of the ovary, fallopian tube, or primary peritoneal cancer. Many patients ask about bevaneal 400mg cost, which may vary depending on hospital supply and location.

The bevaneal cancer protocol and dose schedule are decided by the oncologist based on the cancer type, stage, and body weight. This medicine should be avoided for 28 days before and after surgery due to poor wound healing and bleeding risk. Common Bryxta 200mg Injection side effects include high blood pressure, tiredness, protein in urine, and bleeding. Inform the doctor immediately if you develop vision changes or confusion.

Uses

Bryxta 200mg Injection is indicated to treat the following conditions:

  • Glioblastoma multiforme (brain cancer)

  • Persistent, recurrent, or metastatic breast cancer

  • Metastatic cervical cancer

  • Advanced kidney cancer

  • Metastatic colorectal cancer

  • Advanced non-small-cell lung cancer

  • Liver Cancer- Hepatocellular carcinoma

  • Cancers of the ovary, cervical, fallopian tube, or primary peritoneal cancer

How Bryxta 200mg Injection works 

Bryxta 200mg Injection is a recombinant humanized monoclonal antibody that works as a targeted therapy in the treatment of various advanced cancers. It produces its action by selectively binding to the protein called vascular endothelial growth factor A (VEGF-A), which is present in the lining of blood and lymph vessels in the body. It interrupts the interaction of VEGF-A with its receptors. This further inhibits the formation of blood vessels that supply oxygen and nutrients to the tumour. As a result, it slows down the rate of progression of cancer.

Interaction of Bryxta 200mg Injection with other drugs

Inform your doctor about any medications you are taking or have taken before the treatment.

Storage Conditions

  • Store Bryxta 200mg Injection at 2˚C to 8˚C. Do not freeze or shake.

  • Protect from light. Keep out of reach of children.

How to use Bryxta 200mg Injection

Your physician or nurse will administer Bryxta 200mg Injection as an intravenous infusion. The infusion should be given immediately after the dilution.

Safety advice

Pregnancy-Unsafe

Pregnancy

Unsafe

Inform your physician before starting your treatment with Bryxta 200mg Injection in case, if you are pregnant or planning for pregnancy as this medicine may cause harm to the unborn baby and interrupt the formation of blood vessels.

Breast Feeding-Unsafe

Breast Feeding

Unsafe

It is recommended to avoid breastfeeding for a minimum of 6 months after your treatment with Bryxta 200mg Injection as this medicine may interfere with the growth of your child.

Lungs-Consult Your Doctor

Lungs

Consult Your Doctor

Inform your physician before starting Bryxta 200mg Injection if you have lung diseases to avoid any serious side effects.

Liver-Consult Your Doctor

Liver

Consult Your Doctor

Inform your physician before starting Bryxta 200mg Injection if you have liver disease to avoid any serious side effects.

Alcohol-Consult Your Doctor

Alcohol

Consult Your Doctor

Consult your doctor to know if it is safe to consume while you are on treatment with Bryxta 200mg Injection, as only limited studies are available.

Driving-Unsafe

Driving

Unsafe

Avoid driving or using machinery while you are on your treatment with Bryxta 200mg Injection as it is related to causing dizziness or sleepiness.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. The side effects of Bryxta 200mg Injection is listed below:

 

Serious:

  • Headache

  • Vision changes

  • Confusion

  • Severe allergic reactions

  • High Blood pressure 

  • Delayed wound healing following surgery 

  • Protein in urine 

  • Severe infections 

  • Blood clots in arteries and blood vessels of lungs

  • Gut perforation

  • Nosebleeds and bleeding risk

  • Heart problems with an increase in heart rate 

  • Mouth sores, dryness 

  • Shortness of breath


Common:  

  • Numbness in hands or feet

  • Weakness and lack of energy

  • Diarrhoea, nausea, vomiting, abdominal pain

  • Constipation

  • Loss of appetite

  • Weight loss

  • Changes in taste and speech

  • Decrease in counts of white blood cells

  • Fever

  • Dry skin

  • Back pain

Expert Tips

It is vital to inform your physician before taking Bryxta 200mg Injection if you have the following conditions:

  • Have conditions involving inflammation in the stomach (ulcer, colitis).

  • Experience allergic reactions to Abevmy 100mg or its ingredients.

  • Have recently undergone surgery as it is associated with the risk of bleeding.

  • Have diabetes, hypertension, or heart problems.

FAQs

Q1.

Is Bryxta 200mg Injection used as a standalone treatment in cancers?

Bryxta 200mg Injection is a recombinant monoclonal antibody that belongs to the immunotherapy class of cancer treatment. It can either be used as monotherapy or in combination with chemotherapy or immunotherapy medications to improve the overall survival rate.

Q2.

Is it safe for women to use Bryxta 200mg Injection?

While for women with reproductive potential subjected to Bryxta 200mg Injection, it is advised to discuss with your doctor regarding the effective birth control methods during the treatment. Also to be continued for a minimum of 6 months after the treatment course completion as this medicine may impair fertility.

Q3.

Is it safe to undergo a surgery during the treatment with Bryxta 200mg Injection?

Bryxta 200mg Injection is associated with increased risk of bleeding complications and poor wound healing. Hence it is suggested to avoid planning for surgery and maintain an interval of 28days before or after surgery.

Q4.

Do the side effects of Abevmy 100mg  Injection last for a chronic period?

All the side effects that are relatively caused by Bryxta 200mg Injection occur until the drug concentration stays in the body. It is found that this medicine will be contained in our body for almost 4 months after the final dose.

Q5.

How is Bryxta 200mg Injection administered?

Bryxta 200mg Injection is given intravenously through infusion and the amount of drug will be measured based on the patient’s body weight, height and age.  The first dose will be administered for 90 minutes and if well tolerated the infusion time can be reduced to 30 minutes.

Q6.

Can I take Abevmy 100mg if I am pregnant?

Inform your physician before starting your treatment with Bryxta 200mg Injection in case, if you are pregnant or planning for pregnancy as this medicine may cause harm to the unborn baby and interrupt the formation of blood vessels.

Fact Box

Molecule Name 

Bevacizumab

Therapeutic Classification 

Anticancer

Pharmacological Classification

VEGF Inhibitor

Indications 

Lung cancer, brain cancer, breast cancer, colorectal cancer

Manufacturer 

Astrazeneca

References

1. Roche Products Limited, Electronic Medicines Compendium (EMC), [Revised on Jan 2022] [Accessed on 21/11/2022], https://www.medicines.org.uk/emc/files/pil.3885.pdf

2. G.G. Dark, A.R. Abdul Razak, Oncology, Davidson's Principles & Practice of Medicine, 22nd Edition, 2014, 259-282.

3. KD Tripathi, Anticancer Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019, 915-936.

4. Edward Chu, Cancer Chemotherapy, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976.

5. Roche Group, U.S FDA, [Revised on Jan 2021][ Accessed on 21/11/2022], https://www.gene.com/download/pdf/avastin_prescribing.pdf

6. Roche Group,Bevacizumab Injection, Indication,[Revised on 2020] [Accessed on 21/11/2022]https://www.avastin.com/patient/mcrc.html 

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MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.

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