CABOPROST 250MG INJECTION

Introduction:

Caboprost 250mg Injection contains the active constituent carboprost tromethamine. It is used to stop the excessive bleeding due to the womb failing to return to its normal size in women who have just given birth. Talk to your doctor if you have lung disorders (asthma), high or low blood pressure, heart disorders, glaucoma (raised pressure in your eyes), diabetes, epilepsy, liver disorders, kidney disorders, or had any operation on your womb before taking this medicine. Administration of this medicine may lead to an increase in temperature and bronchoconstriction. Your physician may give other medications to lower this medication's common side effects, such as diarrhea or nausea.

Uses of Caboprost 250mg Injection:

• Used to stop the excessive bleeding in women who have just given birth

How Caboprost 250mg Injection works: 

Caboprost 250mg Injection is a synthetic prostaglandin. It increases the contraction of the womb, which helps to control bleeding after delivery.

Interactions with other drugs:

Inform your doctor about any medications you are taking or have taken before the treatment.

More information:

• Store refrigerated at 2° to 8° C (36° to 46° F). 
• Keep out of sight and reach of children.

References:

1. KD Tripathi, Essentials of Medical Pharmacology, Prostaglandins, Leukotrienes and Platelet activating factor, 7th edition, 2013, 189.
2. Pfizer, Electronics Medicines Compendium (emc), [Revised date: MAR 2021], [ Accessed date: 29 APR 2021], https://www.medicines.org.uk/emc/files/pil.1084.pdf
3. Pfizer, US Food, and Drug Administration, [ Revised date: DEC 2013], [ Accessed date: 29 APR 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/017989s019lbl.pdf

How to use Caboprost 250mg Injection :

It will be given intramuscularly to you by your health care professional.

Safety advice:

Pregnancy: 

It will only be given shortly after you have delivered your baby and not while you are still pregnant as it could put the embryo or foetus at risk.

Breastfeeding:

It is not known if this medicine is excreted in breast milk. And since prostaglandins are produced by your body during childbirth,  is not expected to cause any harm to your baby

Liver:

It is essential to inform if you have any liver disorders before taking Caboprost 250mg Injection.

Kidney:

It is essential to inform if you have any kidney disorders before taking Caboprost 250mg Injection.

Side effects are unwanted symptoms caused by medical treatment. Although all medicines can cause side effects, everyone will not get them. 

Serious:

• Decreases in maternal arterial oxygen content
• Gasping syndrome
• Bronchoconstriction
• Slow heart rate

Common:

• Diarrhea, nausea, and vomiting
• Increased body temperature, Chills
• Headache
• Flushing
• Coughing
• Bleeding from the uterus
• Retained placenta or membranes
• Inflammation of the uterus