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Cabotriq 20mg Tablet
Last updated on 31 Mar 2026 | 09:29 AM (IST)
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Introduction
Cabotriq 20mg Tablet is an antineoplastic medicine containing cabozantinib, a tyrosine kinase inhibitor used in adults to treat advanced kidney cancer, locally advanced or metastatic differentiated thyroid cancer, and liver cancer when sorafenib is no longer effective, often in combination with nivolumab for kidney cancer. Patients frequently ask about Cabotriq tablet benefits, which include slowing cancer growth by blocking signals that help cancer cells survive, as well as details on Cabotriq dosage for cancer, which is decided by the doctor based on the condition and tolerance, including comparisons such as Cabotriq 20mg vs 40mg. Information on Cabotriq 20mg price and Cabotriq 20mg Tablet price in India may vary depending on pharmacy and availability. Like other targeted cancer therapies, Cabotriq side effects can include diarrhea, high blood pressure, fatigue, and mouth sores, so close medical monitoring is required. This medicine is not recommended for patients under 18 years, during pregnancy, or without effective contraception, and patients should inform their doctor about liver disease, heart conditions, thyroid problems, recent surgeries, or lactose intolerance before starting treatment, while also avoiding grapefruit products during therapy.
Uses
The Cabotriq 20mg Tablet is used in the treatment of the following:
Advanced renal cell carcinoma
Liver Cancer
Differentiated thyroid cancer
How Cabotriq 20mg Tablet works
It acts against a protein called receptor tyrosine kinases and interferes with cell signaling, ultimately stopping the growth and spread of cancer cells. Cazanat 40mg is indicated alone or in combination with Nivolumab.
Interaction of Cabotriq 20mg Tablet with other drugs
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications such as antibiotics, St, John's Wort, Aliskiren and other medicine may interact with Cazanat 40mg and can cause undesirable side effects.
Storage conditions
Keep out of sight and reach of pets and children
Store protected from light at a temperature not exceeding 30°C.
How to take Cabotriq 20mg Tablet
Take Cabotriq 20mg Tablet as advised by your physician. Usually, this medicine will be given once a day. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking this medicine if your doctor advises you to stop.
Safety Advices
Pregnancy
Cabotriq 20mg Tablet is unsafe to use during pregnancy as it may harm the unborn baby. Report to your doctor if you are pregnant or think you may be pregnant or planning for the pregnancy before starting the treatment.
Breast Feeding
Taking Cabotriq 20mg Tablet while breastfeeding may be unsafe because it may affect the child. Do not breastfeed for at least four months after the treatment. Therefore, talk with your doctor to get more information.
Lungs
It is unknown whether Cabotriq 20mg Tablet is safe to administer in patients with lung problems. Inform your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.
Liver
Inform your physician if you have liver problems because Cabotriq 20mg Tablet should be used cautiously with this condition.
Alcohol
It is unknown whether consuming alcohol while taking a Cabotriq 20mg Tablet is safe. Please speak with your physician.
Driving
While taking Cabotriq 20mg Tablet, it is unsafe to drive or use machines because it may cause nausea, changes in vision, vomiting, etc. Talk to your doctor for more information.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious side effects of Cabotriq 20mg Tablet are:
Gastrointestinal perforation
Severe or uncontrollable bleeding
Shortness of breath
Nonhealing wound
Pain in the mouth, jaw/teeth, hand, feet,
Loss of consciousness,
Drowsy
Swelling or sores in the mouth
Blood vomiting
Black stools
Blood in urine
Headache
Coughing blood
Common side effects of Cabotriq 20mg Tablet are:
Dehydration
Difficulty swallowing
Ringing in the ears
Blood clots in the veins
Fluctuation in the blood sugar levels
The lower level of albumin
Electrolyte imbalance
Increased levels of liver enzymes
Elevated cholesterol levels in the blood
Hair loss
Changes in hair color
Muscle spasm
Skin thickening
Dry skin
Itching
Protein in urine
Expert tips
Oral contraceptives may be less effective during treatment with Cabotriq 20mg Tablet.
Discuss suitable contraception methods and any fertility concerns with your doctor.
Inform your doctor if you have a thyroid condition, as thyroid function requires regular monitoring.
Tell your doctor if you notice increased fatigue, sensitivity to cold, or a deepening of your voice.
Do not stop taking the medicine unless advised by your doctor.
Report any serious side effects immediately to your healthcare provider.
Your doctor may adjust the dose or stop treatment if needed.
This medicine is not recommended for children or adolescents.
FAQs
Q1.
Can Cabotriq 20mg Tablet cause a lower level of albumin?
One of the common side effects of Cabotriq 20mg Tablet is the lower level of albumin. If you experience any side, contact your physician immediately.
Q2.
Why is it recommended to use effective contraception during the treatment of Cabotriq 20mg Tablet?
To avoid unwanted pregnancy, it is advised to use effective contraception. Oral contraception may be ineffective, so it is better to discuss effective contraception with your doctor.
Q3.
Why is liver enzyme getting elevated during treatment with Cabotriq 20mg Tablet?
The reason for this elevation is not completely understood, but it is thought to be related to the drug's effects on certain enzymes involved in liver function. The elevation in liver enzymes is generally mild and temporary and typically resolves on its own or with dose adjustment of the Cabotriq 20mg Tablet.
Q4.
How can I manage diarrhea while taking Cabotriq 20mg Tablet?
If you experience diarrhea while taking Cabotriq 20mg Tablet, staying hydrated by drinking plenty of fluids is important. Your doctor may also recommend over-the-counter or prescription medications to help manage your diarrhea. If your diarrhea is severe or persistent, you should contact your doctor.
Q5.
Is Cabotriq 20mg Tablet a chemotherapy drug?
Yes, Cabotriq 20mg Tablet is a chemotherapy medication that belongs to the group of Tyrosine kinase inhibitors.
Fact Box
Molecule Name | Cabozantinib |
Therapeutic class | Antineoplastics |
Pharmacological class | Tyrosine kinase inhibitor |
Indications | 1. Advanced renal cell carcinoma 2. Liver Cancer 3. Differentiated thyroid cancer |
References
Ipsen Pharma, Electronic Medicines Compendium (EMC), [Revised on July 2022] [Accessed on 25th April 2023], Cabometyx 20 mg Film-coated Tablets - Summary of Product Characteristics (SmPC) - (emc) (medicines.org.uk)
Exelixis, Inc., [Revised on Oct 2020] [Accessed on 25th April 2023], https://www.cometriq.com/downloads/Cometriq_Full_Prescribing_Information.pdf
Gregory A. Brent and Ronald J. Koenig, Thyroid and Antithyroid Drugs, Goodman & Gilman’s Pharmacological Basis of Therapeutics, 2018, 787-801.
Disclaimer
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Author Details
Written By
Dr. Vikas B S
Pharm D
Reviewed By
Dr. Abhishaanth Prabu
MBBS
Last updated : 31 Mar 2026 | 09:29 AM (IST)
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