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Cabotriq 40mg Tablet

Prescription Required
cabozantinib

6328

MRP: 8437.5

(You Save ₹2109.5)

30 TABLET(s) IN A BOTTLE

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Cabotriq 40mg Tablet
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6328

MRP: 8,437.50

Inclusive of all taxes

25% Off

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30 Tablet(...

30 Tablet(s) In A Bottle

210.9/Unit
Prescription Required
Prescription Required

Salt Composition

CABOZANTINIB

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LUCIEN LIFE SCIENCES

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Introduction

Cabotriq 40mg Tablet is an antineoplastic medicine containing cabozantinib, a tyrosine kinase inhibitor used in adults to treat advanced kidney cancer, locally advanced or metastatic differentiated thyroid cancer, and liver cancer when sorafenib is no longer effective, often in combination with nivolumab for kidney cancer. Patients frequently ask about Cabotriq tablet benefits, which include slowing cancer growth by blocking signals that help cancer cells survive, as well as details on Cabotriq dosage for cancer, which is decided by the doctor based on the condition and tolerance, including comparisons such as Cabotriq 20mg vs 40mg. Information on Cabotriq 40mg price and Cabotriq 40mg Tablet price in India may vary depending on pharmacy and availability. Like other targeted cancer therapies, Cabotriq side effects can include diarrhea, high blood pressure, fatigue, and mouth sores, so close medical monitoring is required. This medicine is not recommended for patients under 18 years, during pregnancy, or without effective contraception, and patients should inform their doctor about liver disease, heart conditions, thyroid problems, recent surgeries, or lactose intolerance before starting treatment, while also avoiding grapefruit products during therapy.

Uses

The Cabotriq 40mg Tablet is used in the treatment of the following: 

  • Advanced renal cell carcinoma

  • Liver Cancer

  • Differentiated thyroid cancer

How Cabotriq 40mg Tablet works 

It acts against a protein called receptor tyrosine kinases and interferes with cell signaling, ultimately stopping the growth and spread of cancer cells. Cazanat 40mg is indicated alone or in combination with Nivolumab.

Interaction of Cabotriq 40mg Tablet with other drugs

Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications such as antibiotics, St, John's Wort, Aliskiren and other medicine may interact with Cazanat 40mg and can cause undesirable side effects. 

Storage conditions

  • Keep out of sight and reach of pets and children

  • Store protected from light at a temperature not exceeding 30°C.

How to take Cabotriq 40mg Tablet

Take Cabotriq 40mg Tablet as advised by your physician. Usually, this medicine will be given once a day. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking this medicine if your doctor advises you to stop.

Safety Advices

Pregnancy-Consult Your Doctor

Pregnancy

Consult Your Doctor

Cabotriq 40mg Tablet is unsafe to use during pregnancy as it may harm the unborn baby. Report to your doctor if you are pregnant or think you may be pregnant or planning for the pregnancy before starting the treatment. 

Breast Feeding-Consult Your Doctor

Breast Feeding

Consult Your Doctor

Taking Cabotriq 40mg Tablet while breastfeeding may be unsafe because it may affect the child. Do not breastfeed for at least four months after the treatment. Therefore, talk with your doctor to get more information. 

Lungs-Consult Your Doctor

Lungs

Consult Your Doctor

It is unknown whether Cabotriq 40mg Tablet is safe to administer in patients with lung problems. Inform your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.

Liver-Consult Your Doctor

Liver

Consult Your Doctor

Inform your physician if you have liver problems because Cabotriq 40mg Tablet should be used cautiously with this condition.

Alcohol-Consult Your Doctor

Alcohol

Consult Your Doctor

It is unknown whether consuming alcohol while taking a Cabotriq 40mg Tablet is safe. Please speak with your physician.

Driving-Consult Your Doctor

Driving

Consult Your Doctor

While taking Cabotriq 40mg Tablet, it is unsafe to drive or use machines because it may cause nausea, changes in vision, vomiting, etc. Talk to your doctor for more information. 

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

Serious side effects of Cabotriq 40mg Tablet are:

  • Gastrointestinal perforation

  • Severe or uncontrollable bleeding

  • Shortness of breath

  • Nonhealing wound

  • Pain in the mouth, jaw/teeth, hand, feet,

  • Loss of consciousness,

  • Drowsy

  • Swelling or sores in the mouth

  • Blood vomiting

  • Black stools

  • Blood in urine

  • Headache

  • Coughing blood

Common side effects of Cabotriq 40mg Tablet are:

  • Dehydration

  • Difficulty swallowing

  • Ringing in the ears

  • Blood clots in the veins

  • Fluctuation in the blood sugar levels

  • The lower level of albumin

  • Electrolyte imbalance

  • Increased levels of liver enzymes

  • Elevated cholesterol levels in the blood

  • Hair loss

  • Changes in hair color

  • Muscle spasm

  • Skin thickening

  • Dry skin

  • Itching

  • Protein in urine

Expert tips

  • Oral contraceptives may be less effective during treatment with Cabotriq 40mg Tablet.

  • Discuss suitable contraception methods and any fertility concerns with your doctor.

  • Inform your doctor if you have a thyroid condition, as thyroid function requires regular monitoring.

  • Tell your doctor if you notice increased fatigue, sensitivity to cold, or a deepening of your voice.

  • Do not stop taking the medicine unless advised by your doctor.

  • Report any serious side effects immediately to your healthcare provider.

  • Your doctor may adjust the dose or stop treatment if needed.

  • This medicine is not recommended for children or adolescents.

FAQs

Q1.

Can Cabotriq 40mg Tablet cause a lower level of albumin?

One of the common side effects of Cabotriq 40mg Tablet is the lower level of albumin. If you experience any side, contact your physician immediately.

Q2.

Why is it recommended to use effective contraception during the treatment of Cabotriq 40mg Tablet?

To avoid unwanted pregnancy, it is advised to use effective contraception. Oral contraception may be ineffective, so it is better to discuss effective contraception with your doctor.

Q3.

Why is liver enzyme getting elevated during treatment with Cabotriq 40mg Tablet?

The reason for this elevation is not completely understood, but it is thought to be related to the drug's effects on certain enzymes involved in liver function. The elevation in liver enzymes is generally mild and temporary and typically resolves on its own or with dose adjustment of the Cabotriq 40mg Tablet.

Q4.

How can I manage diarrhea while taking Cabotriq 40mg Tablet?

If you experience diarrhea while taking Cabotriq 40mg Tablet, staying hydrated by drinking plenty of fluids is important. Your doctor may also recommend over-the-counter or prescription medications to help manage your diarrhea. If your diarrhea is severe or persistent, you should contact your doctor.

Q5.

Is Cabotriq 40mg Tablet a chemotherapy drug?

Yes, Cabotriq 40mg Tablet is a chemotherapy medication that belongs to the group of Tyrosine kinase inhibitors.

Fact Box

Molecule Name

Cabozantinib

Therapeutic class

Antineoplastics

Pharmacological class

Tyrosine kinase inhibitor

Indications

1. Advanced renal cell carcinoma

2. Liver Cancer

3. Differentiated thyroid cancer

References

  1. Ipsen Pharma, Electronic Medicines Compendium (EMC), [Revised on July 2022] [Accessed on 25th April 2023], Cabometyx 20 mg Film-coated Tablets - Summary of Product Characteristics (SmPC) - (emc) (medicines.org.uk)

  2. Exelixis, Inc., [Revised on Oct 2020] [Accessed on 25th April 2023], https://www.cometriq.com/downloads/Cometriq_Full_Prescribing_Information.pdf

  3. Gregory A. Brent and Ronald J. Koenig, Thyroid and Antithyroid Drugs, Goodman & Gilman’s Pharmacological Basis of Therapeutics, 2018, 787-801.

Disclaimer

MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.

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