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Canmab 440mg Injection is indicated for its use in the following conditions:

Advanced and metastatic breast cancer
Metastatic gastric cancer

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The protein called HER2 (human epidermal growth factor receptor 2) is found in abundant amounts on the surface of certain cancer cells, where it stimulates cancer growth. Canmab 440mg Injection selectively binds to HER2 and stops the growth of cancer cells.

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Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional and vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Canmab 440mg Injection and cause undesirable side effects.

"}},{"id":"f4c2ef91-d709-4f48-9b31-c52d3d7acde8","type":"PARA","position":5,"content_placement":1,"data":{"heading":"More Information about Canmab 440mg Injection","text":"

Keep Canmab 440mg Injection out of sight and reach of children.
Store between 2˚C and 8˚C.

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Canmab 440mg Injection shall either be administered before or after surgery.
It will be given as an Intravenous infusion for 90 minutes, if well tolerated it shall be administered within 30 minutes for the next doses.

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Avoid breastfeeding your baby while on the treatment with Canmab 440mg Injection atleast for at least seven months after the final dose.

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Consult your doctor to know if it is safe to consume alcohol while you are on treatment with Canmab 440mg Injection.

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You need to tell your physician if you have any liver disorders before starting Canmab 440mg Injection as it requires dosage adjustment for severe liver impairment.

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Talk to your doctor if you have any lung conditions before starting treatment with Canmab 440mg Injection.

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Canmab 440mg Injection can cause unusual tiredness and dizziness. Hence, it is advised to avoid driving or handling machinery during the treatment.

","imageUrl":"https://assets.mrmed.in/others/file-1674132431331-421990512-Driving.jpg"},{"id":"729bfd2f-4f16-4695-aceb-5aa96e1ff83b","advice":"Pregnancy","tag":"unsafe","description":"

Discuss with your physician before taking this Canmab 440mg Injection if you are pregnant or think you might be pregnant. Do not take this medicine during the pregnancy unless advised by the doctor to take as it may cause to the unborn baby.

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Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.

Serious

Heart Problems
Allergic reactions
Kidney problems
Breathing difficulties

Common

Fever
Visual disturbances
Nose bleeds or runny nose
Hair loss
Dizziness
Nail disorders
Weight loss
Loss of appetite
Bruising
Dry mouth
Liver inflammation
Muscle pain
Asthma/ lung disorders

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It is suggested to inform your doctor if you have a history of allergic reactions to Canmab 440mg Injection to avoid life-threatening complications. If you have a history of lung disorder or breathing problems inform your doctor beforehand before the treatment commencement. Avoid planning for pregnancy and breastfeeding for a minimum of 7 months after the last dose. Monitor your heart parameters regularly during the treatment with Canmab 440mg Injection as it may impact the functioning of heart.

"}},{"id":"232f4338-1e60-4628-a3de-51f801e56eca","type":"FAQ","position":10,"content_placement":2,"data":{"heading":"FAQs about Canmab 440mg Injection","faq_list":[{"id":"f456904d-d5e7-4ea3-bea3-13559a5d68cb","question":"

Is Canmab 440mg Injection used as a monotherapy in treating breast cancer?

","answer":"

Canmab 440mg Injection is generally given along with the chemotherapy medication such as paclitaxel or docetaxel or platinum compunds. Sometimes, it is also given with hormonal agents for those patients with elevated hormonal status.

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Does Canmab 440mg Injection cause heart problems?

","answer":"

Yes, Canmab 440mg Injection can damage the heart muscles. Hence to prevent the worsening of symptoms, it is advised to do heart check up every 3 months and continue till 2-5 years after the treatment completion.

"},{"id":"df21a124-2e38-46ff-ad76-1265bed48f87","question":"

Can I breastfeed while on treatment with Canmab 440mg Injection?

","answer":"

No, since tends to pass into breast milk, it is unsafe to breastfeed. Hence, It is advised not to breastfeed for a minimum of 7 months after the treatment with Canmab 440mg Injection.

"},{"id":"b372a8e2-29db-4f73-89a5-8041893e5544","question":"

Can Canmab 440mg Injection be consumed during pregnancy?

","answer":"

No, it is unsafe to consume Canmab 440mg Injection while you are pregnant or this medicine can cause harm to the baby by reducing the amount of amniotic fluid,the fluid surrounding the womb. It can also cause organ developmental issues such as poor lung development when consumed during pregnancy. If you are planning for pregnancy, it is advised to discuss the birth control methods as this medicine may impair your fertility.

"}]}},{"id":"b1865ac7-76d3-43d7-a765-59ee2d8ecfd2","type":"PARA","position":11,"content_placement":3,"data":{"heading":"Fact Box of Canmab 440mg Injection","text":"

Molecule name: Trastuzumab

Therapeutic class: Anti-cancer

Pharmacological class: HER2 inhibitor

Indications:

1. Advanced and metastatic breast cancer

2. Metastatic gastric cancer

"}},{"id":"b2c39cef-6fd4-4824-842b-9bd5820679c8","type":"PARA","position":12,"content_placement":3,"data":{"heading":"References","text":"

1. Roche, Electronic Medicines Compendium (EMC), [Revised on Jan 2022] [Accessed on 12th July 2022], https://www.medicines.org.uk/emc/files/pil.3856.pdf

2. Genentech Inc, [Revised on Feb 2021] [Accessed on 12th July 2022], https://www.gene.com/download/pdf/herceptin_prescribing.pdf

3. Anton Wellstein, Giuseppe Giaccone, Michael B. Atkins, and Edward A. Sausville, Pathway-Targeted Therapies: Monoclonal Antibodies, Protein Kinase Inhibitors, and Various Small Molecules, Goodman & Gilman’s Pharmacological Basis of Therapeutics, 13th Edition, 2018, 1203-1236.

"}},{"id":"e424369b-18ad-46aa-9d1e-08d7a99f360f","type":"DISCLAIMER","position":13,"content_placement":5,"data":{"heading":"Disclaimer","text":"

MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.

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