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Clotnine 600IU Injection

Prescription Required

Salt Composition : Factor Ix

Manufacturer : HEMARUS THERAPEUTICS LTD

Origin of Medicine : India

MRP: ₹13000
Price : ₹9880
You Save : ₹3120 (24%)

1 Vial(s)

Introduction to Clotnine 600iu Injection

Clotnine 600IU Injection  contains active components such as factor IX. In some cases, individuals with hemophilia A (caused by a deficiency of factor VIII) may develop inhibitors (antibodies) against factor VIII, making standard treatment less effective. In such situations, it may be considered as an alternative. It can be used before, during, and after surgery to prevent excessive bleeding. Some people with hemophilia B may receive it  as a preventive measure to maintain a certain level of this in their bloodstream, reducing the risk of spontaneous bleeding episodes, particularly in joints and muscles. It may be administered following traumatic injuries or accidents to prevent or control bleeding. In rare cases, it may be considered for treating other bleeding disorders or conditions that involve a deficiency, such as acquired hemophilia.

If a person has a known allergy or hypersensitivity to Clotnine 600IU Injection or any components of  this product, it is a contraindication to its use.  It is inappropriate for individuals with DIC, a complex bleeding disorder characterized by abnormal clotting and bleeding. People with severe liver disease may not respond well to it, and the risks and benefits should be carefully weighed. While it is commonly used in pediatric patients with hemophilia B, the dosage and administration should be carefully adjusted based on age and weight, and the treatment should be closely monitored. Clotnine 600IU Injection replacement therapy can be safe and effective for older adults with hemophilia B. However, dosing and treatment plans may need to be adjusted based on individual health and medical history.

Uses of Clotnine 600iu Injection

Clotnine 600IU Injection is used in the following:

  • Treatment of hemophilia B
  • Prophylactic treatment
  • Management of bleeding episodes
  • Surgical procedures
  • Trauma and injuries
  • Alternative treatment for hemophilia A with inhibitors
  • Other bleeding disorders
  • Pediatric hemophilia B

Therapeutic Effects of Clotnine 600iu Injection

Once administered, the infused form  Clotnine 600IU Injection, it mixes with the patient's blood, becoming available to participate in the coagulation cascade. In the event of an injury or bleeding episode, it helps initiate and accelerate the formation of a stable blood clot by activating other coagulation factors, ultimately leading to the cessation of bleeding. 

Interaction of Clotnine 600iu Injection with other drugs

Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Clotnine 600IU Injection , reducing effectiveness by causing undesirable side effects. 

More Information about Clotnine 600iu Injection

  • Stored at room temperature from 20°C to 25°C.
  • Keep away from moisture, heat, and light.
  • It should not be frozen.
  • Keep away from children and pets.

How to consume Clotnine 600iu Injection

Clotnine 600IU Injection replacement therapy can be administered through intravenous (IV) infusion or intravenous injection. The choice of administration route depends on the specific Clotnine 600IU Injection product, the patient's age, the severity of hemophilia B, and individual preferences. 

Safety Advices for Clotnine 600iu Injection

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Pregnancy

  

The use of Clotnine 600IU Injection therapy during pregnancy should be discussed with a healthcare provider. The safety and potential risks to the developing fetus should be carefully considered, and treatment options should be weighed.

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Breast Feeding

  

The safety of Clotnine 600IU Injection therapy during breastfeeding should be discussed with a healthcare provider. Considerations should include the impact on the nursing infant and the treatment's potential risks and benefits.

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Lungs

  

If you have a lung problem, consult a healthcare provider before taking Clotnine 600IU Injection.  

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Liver

  

Individuals with severe liver disease should consult their healthcare provider before using Clotnine 600IU Injection.

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Alcohol

  

Excessive alcohol consumption can lead to side effects, so it is not safe to consume alcohol if you are using Clotnine 600IU Injection.

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Driving

  

Individuals on Clotnine 600IU Injection therapy need to be aware of their own limitations and consult with their healthcare provider regarding driving safety.

Side Effects of Clotnine 600iu Injection

Clotnine 600IU Injection  causes some side effects like all medications, although not everyone will experience them. 

Serious

  • Allergic reactions
  • Development of inhibitors
  • Thrombosis (blood clots)
  • Hepatitis transmission
  • Liver complications

Common

  • Localized reactions

Word of Advice

Patient should be aware of the potential for allergic reactions and promptly report any signs, such as hives or difficulty breathing. Regular monitoring of Clotnine 600IU Injection levels is crucial, especially for inhibitor development, as adjustments to the treatment plan may be needed.  Patients with liver or kidney conditions should exercise caution, as should those receiving live vaccines, to avoid potential interactions. In surgical or dental procedures, healthcare providers should be informed to make necessary treatment adjustments. Patients should also be mindful of alcohol intake, especially given its impact on liver function, and practice safe driving. An emergency plan for bleeding episodes and access to psychosocial support can further enhance the safety and well-being of individuals with hemophilia B.

FAQs

Q 1. How often is Clotnine 600IU Injection replacement therapy required?

The frequency of Clotnine 600IU Injection replacement therapy depends on the severity of hemophilia B and the treatment plan developed by healthcare providers. Some individuals may require regular prophylactic treatment, while others only need it when experiencing bleeding episodes.

Q 2. Are there any side effects or risks associated with Clotnine 600IU Injection replacement therapy?

While Clotnine 600IU Injection replacement therapy is generally safe and well-tolerated, there can be risks, including allergic reactions, inhibitor development, and thrombosis (blood clot formation). Patients should discuss potential risks with their healthcare providers.

Q 3. What should I do in case of a bleeding emergency while on Clotnine 600IU Injection therapy?

Individuals on Clotnine 600IU Injection therapy should contact their healthcare provider or seek immediate medical attention if a bleeding emergency occurs. In some cases, they may be trained to administer Clotnine 600IU Injection at home for quick response to bleeding episodes.

Q 4. Can Clotnine 600IU Injection replacement therapy be self-administered at home?

Some individuals with hemophilia B are trained to self-administer Clotnine 600IU Injection at home. This can provide convenience and rapid access to treatment when needed, especially for prophylactic regimens.

Q 5. Are there any dietary restrictions while on Clotnine 600IU Injection therapy?

There are usually no specific dietary restrictions while on Clotnine 600IU Injection therapy. However, maintaining a balanced diet and staying hydrated can support overall health and well-being for individuals with hemophilia B.

Q 6. Is participating in sports and physical activities possible while on Clotnine 600IU Injection therapy?

With proper management and treatment, individuals with hemophilia B can participate in sports and physical activities. They should work closely with their healthcare providers to develop a safe exercise regimen and take precautions to prevent injuries.

Fact Box of Clotnine 600iu Injection

Molecule name:   Factor IX     

Therapeutic class: Hemostatic Agent

Pharmacological class:  Coagulation Factor - Antihemorrhagic

Indications:  

1. Treatment of hemophilia B 

2. Prophylactic treatment

3. Management of bleeding episodes 

4. Surgical procedures 

5. Trauma and injuries 

6.Alternative treatment for hemophilia A with inhibitors 

 7.Other bleeding disorders 

8. Pediatric hemophilia B 

References

  1. Octapharma Limited, Electronic Medicines Compendium (EMC), [Revised on 04 Jan 2022] [Accessed on 2nd September 2023], https://www.medicines.org.uk/emc/product/6566/smpc#gref
  2. NA Orlova et al; Factor IX  for Haemophilia B therapy; Acta Naturae 2012; [Accessed: 2nd September 2023], https://pubmed.ncbi.nlm.nih.gov/22872812/
  3. T Zögg; Activation mechanisms of coagulation factor IX; Biological Chemistry 2009; [Accessed:2nd September 2023]], https://pubmed.ncbi.nlm.nih.gov/193612

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