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Comfora 100mg Capsule
Last updated on 31 Mar 2026 | 09:31 AM (IST)
₹624
MRP: ₹693.75
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Comfora 100mg Capsule
Salt Composition
PENTOSAN POLYSULFATE SODIUMMarketer
SWATI SPENTOSE PVT LTD
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MRP: ₹693.75
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Introduction to Comfora 100mg Capsule
Comfora 100mg capsule contains an active component called Pentosan polysulfate sodium. It is primarily known for treating interstitial cystitis or painful bladder syndrome, a chronic condition that causes pain and discomfort in the bladder and pelvis. It is believed to form a protective coating on the bladder lining, helping to reduce irritation and inflammation. This protective effect may contribute to its efficacy in managing IC symptoms. It is thought to have anti-inflammatory and cartilage-protective properties. It has anticoagulant properties and has been studied for its potential use in preventing blood clots. It may be considered a preventive measure in individuals at risk of DVT (Deep vein thrombosis) or PE (Pulmonary Embolism), especially in cases where other anticoagulants are unsuitable. It may be used in the management of bladder pain syndrome symptoms.
It should not be used in individuals with known hypersensitivity or allergy to Comfora 100mg capsule or its components. It has anticoagulant properties and can increase the risk of bleeding. It should be avoided in individuals with active bleeding disorders, such as hemophilia, thrombocytopenia( low platelet count in the blood.), or other bleeding tendencies. It should not be initiated immediately following major surgical procedures or spinal puncture because of its anticoagulant effects, which could increase the risk of bleeding at the surgical site or spinal canal. It is primarily eliminated through the kidneys. Therefore, caution is advised in individuals with severe renal impairment, as impaired kidney function can affect the drug's clearance from the body. Safety and effectiveness in pediatric patients below the age of 16 years have not been established. Regular monitoring and dose adjustments should be considered in older individuals before taking Comfora 100mg capsule if necessary.
Uses of Comfora 100mg Capsule
Comfora 100mg capsule is used in the following:
- Interstitial cystitis
- Painful bladder syndrome
Therapeutic Effects of Comfora 100mg Capsule
Comfora 100mg capsule primarily works in treating interstitial cystitis (IC) by forming a protective barrier on the bladder's inner lining. This protective barrier helps reduce irritation and inflammation in the bladder, alleviating the symptoms associated with IC, such as pelvic pain, urinary urgency, and frequency.
Interaction of Comfora 100mg Capsule with other drugs
Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Comfora 100mg capsule, reducing effectiveness by causing undesirable side effects.
More Information about Comfora 100mg Capsule
- Stored at room temperature from 20°C and 25°C
- Keep away from moisture, heat, and light.
- It should not be frozen.
- Keep away from children and pets.
How to consume Comfora 100mg Capsule
Comfora 100mg capsule is typically administered orally in the form of capsules or tablets. However, in cases of bladder-related conditions like interstitial cystitis can also be delivered directly into the bladder through a catheter (intravesical administration). The choice of administration route depends on the specific medical condition and treatment plan.
Safety Advice for Comfora 100mg Capsule
Breast Feeding
It is unclear whether Comfora 100mg capsule passes into breast milk, and the potential risks to the nursing infant are poorly understood. Breastfeeding women should consult with a healthcare provider before using this medication.
Alcohol
Alcohol consumption should be moderated, especially in older adults, as excessive alcohol intake can increase the risk of bleeding and may increase Comfora 100mg capsule-related side effects. Consult a healthcare provder before taking this medication with alcohol.
Liver
Individuals with liver conditions should consult with their healthcare provider before taking Comfora 100mg capsule.
Lungs
No specific contraindication related to lung health exists. However, individuals with respiratory conditions should consult a healthcare provider, as there may be a risk of bleeding that could affect lung function.
Driving
Comfora 100mg capsule is not known to impair the ability to drive or operate machinery. However, individual responses to medications can vary, so individuals should consult a healthcare provider before taking this medication while driving.
Pregnancy
Due to limited safety data, Comfora 100mg capsule is generally not recommended during pregnancy. The potential risks to the fetus should be carefully weighed against the expected benefits, and its use should be discussed with a healthcare provider.
Side Effects of Comfora 100mg Capsule
Comfora 100mg capsule causes some side effects like all medications, although not everyone will experience them.
Serious
- Bleeding disorders
- Liver damage
- Allergic reactions
Common
- Gastrointestinal disturbances
- Headache
- Unusual taste
Word of Advice
Use caution or avoid Comfora 100mg capsule if you have a known hypersensitivity or allergy to the medication. If you have a history of bleeding disorders or take anticoagulants, be cautious; this medication may increase the risk of bleeding. Avoid it immediately after major surgery or spinal puncture due to its potential to cause bleeding. Use it carefully and consider monitoring liver function if you have liver or renal impairment. It's generally not recommended during pregnancy or breastfeeding, so consult your healthcare provider. This medication is typically not used in children, and individuals with respiratory conditions should use it cautiously. Avoid excessive alcohol intake. Assess your individual response to this medication before engaging in activities requiring concentration. Always consult with your healthcare provider to ensure safe and appropriate use.
FAQs about Comfora 100mg Capsule
Q1.
Can I stop taking Comfora 100mg capsule once my IC symptoms improve?
Following your healthcare provider's recommendations regarding the duration of Comfora 100mg capsule treatment duration is essential. Stopping the medication abruptly may lead to a recurrence of symptoms.
Q2.
Are there any dietary restrictions while taking Comfora 100mg capsule Comfora?
While there are no specific dietary restrictions are associated with Comfora 100mg capsule, some individuals with IC find that certain foods and beverages can trigger or worsen their symptoms. Discuss dietary considerations with your healthcare provider.
Q3.
What should I do if I miss a dose of Comfora 100mg capsule?
If you miss a dose of Comfora 100mg capsule, take it as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
Q4.
Can Comfora 100mg capsule be used as a preventive measure for blood clots?
Comfora 100mg capsule has anticoagulant properties and may be considered in specific medical situations for preventing blood clots. However, a healthcare provider should determine its use for this purpose.
Q5.
Is Comfora 100mg capsule available over-the-counter (OTC), or do I need a prescription?
Comfora 100mg capsule is typically available by prescription, and its use should be supervised by a healthcare provider who can assess your specific medical needs.
Q6.
What should I do if I experience a severe side effect or allergic reaction to Comfora 100mg capsule?
If you experience severe side effects or signs of an allergic reaction (e.g., rash, swelling, difficulty breathing) to Comfora 100mg capsule, seek immediate medical attention and discontinue the medication
Fact Box of Comfora 100mg Capsule
Molecule name: Pentosan polysulfate sodium
| Therapeutic class: Bladder protectants |
Pharmacological class: Heparinoid anticoagulants | Indications: 1. Interstitial cystitis 2. Painful bladder syndrome |
References
- Janssen Pharmaceuticals, Inc, US Food and Drug Administration, [Revised on June 2020] [ Accessed on 13th September 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/020193s014lbl.pdf
- bene-Arzneimittel GmbH, European Medicines Agency (ema), [Issued on June 2017] [Accessed on 13th September 2023], https://www.ema.europa.eu/en/documents/product-information/elmiron-epar-product-information_en.pdf
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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Author Details
Written By
Dr. Archana Gupta
BDS
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 31 Mar 2026 | 09:31 AM (IST)
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