Cort-S 100mg Injection contains the active constituent Hydrocortisone. It is used to treat primary or secondary adrenocortical insufficiency and Congenital adrenal hyperplasia (in which adequate steroid hormones are not produced). It is useful to treat arthritis, skin diseases, allergic conditions, eye diseases, respiratory diseases, cancer conditions, disorders affecting blood, gastrointestinal diseases, and collagen disorders. 

Cort-S 100mg Injection may mask the signs of infections, and new infections may appear during the use. Prolonged use of the medicine may lead to eye-related problems. Avoid vaccination during the treatment with this medicine. Tell your doctor if you have any fungal infections before taking medicine. It is important to inform your allergic conditions and diseases to your doctor before taking this medication.  Avoid exposure to people who have chickenpox, measles, or shingles during the treatment. Consult your doctor if you experience mental health problems while taking medicine. This medicine contains lactose. Ask for a doctor’s advice if you are intolerant to sugars.

• Adrenocortical insufficiency
• Congenital adrenal hyperplasia
• Arthritis (inflammation of joints)
• Allergic conditions
• Inflammatory disease of the eye
• Certain cancer conditions
• Gastrointestinal diseases
• Collagen disorders like SLE (systemic lupus erythematosus)
• Skin problems like eczema, psoriasis, and dermatitis
• Asthma

Cort-S 100mg Injection is a corticosteroid hormone (naturally occurring hormone cortisol), which is produced by the adrenal gland. Cortisol plays an important role in regulating inflammation and immune function. When there is an injury or infection, the body responds by increasing inflammation and immune activity to help fight off the threat. However, the inflammatory response can sometimes become excessive or misguided, leading to tissue damage or autoimmune disorders. This medication works by binding to specific receptors in the body and inhibiting the production of inflammatory chemicals and immune cells, thus reducing inflammation and suppressing the immune response. This can relieve pain, swelling, and redness and help prevent tissue damage and further complications.

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Cort-S 100mg Injection and reduce effectiveness by causing undesirable side effects.

• Cort-S 100mg Injection should be stored at room temperature between 5-25°C (68-77°F).
• Keep away from heat, moisture, and light.
• Store in an original package.
• Keep out of reach of children and pets.

Cort-S 100mg Injection is given as an intravenous or intramuscular injection by a healthcare professional. If you miss a dose, taking or applying it as soon as you remember is important. However, if it is close to the time for your next dose, it is best to skip the missed dose and resume your regular schedule. Do not double the dose to make up for the missed one.

Like all medications, Cort-S 100mg Injection can cause side effects, although not everyone who takes it will experience them. 

Serious:

• Itching or skin rashes
• Swelling of lips, throat, or face
• Difficulty in breathing
• Depression and mood swings
• Cushing’s syndrome (reddish stretch marks, round red face, weak bones, and muscles)
• Bleeding ulcer (stomach pain, black stools, bleeding from back passage)
• Aseptic necrosis (hip or shoulder pain, joint inflammation of knee or groin)
• Inflammation of the pancreas

Common:

• Headaches, dizziness
• Swollen ankles
• Feeling tiredness
• Increased appetite and weight gain
• Fluid retention and swelling in the face and limbs
• Elevated blood pressure
• Difficulty sleeping or insomnia
• Acne
• Increased susceptibility to infections
• Muscle weakness or wasting

Cort-S 100mg Injection is a prescription medication that should only be used under the guidance and supervision of a qualified healthcare professional. Do not share your medication with others, and do not use it for any condition other than the one for which it was prescribed. Do not take more or less of the medication than prescribed, and do not stop taking the medication without first consulting with your healthcare professional.

Inform your healthcare professional immediately if you experience any side effects or have any safety concerns, particularly if you have a history of liver disease, kidney disease, diabetes, or other medical conditions. They may need to adjust your dose or recommend an alternative treatment to ensure your safety and optimize treatment outcomes. If you have any questions or concerns about using this medication, speak with your healthcare professional.

1. KD Tripathi, Essentials of Medical Pharmacology, Corticosteroids, 7th edition, 513,282 - 293.
2. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, ACTH, Adrenal Steroids and Pharmacology of the Adrenal Cortex,12th edition, 511, 1228-1229.
3. Focus Pharmaceuticals Limited, Electronic medicines compendium (EMC), [ Revised on May 519] [ Accessed on 13 April 553], https://www.medicines.org.uk/emc/files/pil.3065.pdf
4. Pfizer, US Food and Drug Administration, [ Revised on Nov 519] [ Accessed on 13th April 523], https://www.accessdata.fda.gov/drugsatfda_docs/label/519/008697s036lbl.pdf