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Cuchel 250mg Capsule
Last updated on 07 Sep 2026 | 11:46 AM (IST)
₹18657
MRP: ₹22646.25
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100 CAPSULE(s) IN A BOTTLE
Cuchel 250mg Capsule
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₹18657
MRP: ₹22,646.25
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Introduction to Cuchel 250mg Capsule
Cuchel 250mg capsule contains the active constituent Trientine Hydrochloride. It is a copper chelator used to treat adult patients with stable Wilson’s disease who cannot tolerate any medicine used to treat this disease. Wilson’s disease is an inherited condition in which the body cannot transport copper around the body in normal ways or remove copper normally as a secretion from the liver into the gut. This means that the small amounts of copper from food and drink build up to excessive levels and can lead to liver damage and problems in the nervous system.
This medicine mainly works by attaching to copper in the body, allowing it to be removed in the urine instead, helping to lower copper levels. It may also attach to copper in the gut and reduce the amount taken into the body. Do not take this medicine if you are allergic to Trientine Hydrochloride or any other ingredients in this medicine. Cuchel 250mg capsule may also reduce the iron level in your blood; you may be prescribed iron supplements. Inform your physician if you have kidney or liver problems, breathing problems, dermatitis (red and itchy skin), or anemia, if you are pregnant or breastfeeding.
Uses of Cuchel 250mg Capsule
- Wilson’s disease
Therapeutic Effects of Cuchel 250mg Capsule
Cuchel 250mg capsule is a copper chelating agent that binds excess copper in the body and assists in elimination from the body. It may also work by attaching to the copper in your stomach and stopping it from being absorbed.
Interaction of Cuchel 250mg Capsule with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications may interact with Cuchel 250mg capsule and reduce its effectiveness by causing undesirable side effects.
More Information about Cuchel 250mg Capsule
- Store this Cuchel 250mg capsule at room temperature 20°C to 25°C
- Keep the medicine out of reach of children and pets
- If you forgot to take the tablet, simply take your next dose at the scheduled time. Do not take a double dose to make up for a forgotten dose.
How to consume Cuchel 250mg Capsule
Your doctor will decide the dose and duration of Cuchel 250mg capsule based on the disease condition and other factors. Always take this medicine as prescribed by your doctor. Swallow the capsules with water on an empty stomach (at least one hour before meals or two hours after meals, and at least one hour apart from any other medicines, food, or milk.) Do not break, chew, crush, or break the tablet.
Safety Advice for Cuchel 250mg Capsule
Breast Feeding
Breastfeeding is not recommended in patients taking Cuchel 250mg capsule because the medicine passes into the breast milk in small amounts and may harm your baby.
Alcohol
It is unknown whether consuming alcohol is safe when taking Cuchel 250mg capsule. Inform your physician if you are an alcoholic before starting the treatment.
Liver
It is unknown whether Cuchel 250mg capsule can be used in patients with liver disorders. Consult your doctor if you have any liver diseases before starting the treatment.
Lungs
It is unknown whether Cuchel 250mg capsule can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
Driving
Cuchel 250mg capsule does not affect the ability to drive or operate heavy machinery if you feel dizzy after taking the medicine. Consult your doctor for more advice.
Pregnancy
Do not take Cuchel 250mg capsule if you are pregnant because this may harm the unborn baby. Inform your physician if you are pregnant, suspecting pregnancy, or planning to get pregnant during the treatment.
Side Effects of Cuchel 250mg Capsule
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Common
- Abdominal pain
- Change of bowel movements
- Rash
- Alopecia
- Mood swings
- Difficulty in moving
- Muscle pain
Serious
- Iron deficiency anemia
- Hypersensitivity skin reactions
Word of Advice
Avoid concomitant use of mineral supplements like iron, zinc, calcium, and magnesium. Consult your physician before taking any vitamin or mineral supplements. Take this medicine at least 2 hours before or 2 hours after taking iron supplements or 1 hour before or 2 hours after taking other supplements like calcium, magnesium, or zinc. This medicine may cause copper or iron deficiency. Your doctor will do lab tests at regular visits to check on the effects of this medicine.
FAQs about Cuchel 250mg Capsule
Q1.
Can I receive vaccination while taking Cuchel 250mg capsule?
Limited data is available on vaccination use during Cuchel 250mg capsule therapy. Consult your doctor before receiving any vaccines.
Q2.
What is the difference between Cuchel 250mg capsule and penicillamine?
Penicillamine is used therapeutically to re-establish copper balance; trientine is indicated for patients with penicillamine intolerance. Your doctor will decide which medicine works best for you.
Q3.
Can I take vitamin or mineral supplements with Cuchel 250mg capsule?
Avoid taking supplements concomitantly with Cuchel 250mg capsule. Take this medicine at least 2 hours before or after taking vitamin or mineral supplements.
Q4.
Will Cuchel 250mg capsule increase the body temperature?
The patient should check their body temperature each night during the first month of therapy and report the occurrence of fever.
Q5.
What is Cuchel 250mg capsule used to treat?
Cuchel 250mg capsule is an orally available copper-chelating agent that is used to treat Wilson disease, an inherited abnormality of copper metabolism that leads to excess copper accumulation and injury to the liver and brain.
Fact Box of Cuchel 250mg Capsule
Molecule name: Trientine hydrochloride | Therapeutic class: Copper Chelators |
Pharmacological class: Chelating Agents | Indications: Wilson’s disease |
References
- Trientine dihydrochloride Tillomed 250 mg capsules, hard - Summary of Product Characteristics (SmPC) - (emc). www.medicines.org.uk. [cited 2023 Apr 3]. Available from: https://www.medicines.org.uk/emc/product/11626/smpc
- HIGHLIGHTS OF PRESCRIBING INFORMATION. Food and Drug Administration - Trientine hydrochloride. [revised on 2022] [cited 2023 Apr 3]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/215760s000lbl.pdf
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Environmental toxicology: Carcinogenesis and Heavy metals, 12th edition, 2011, 1875.
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Author Details
Written By
Guruvigneshwari M.
M. Pharm
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 07 Sep 2026 | 11:46 AM (IST)
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