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Cuchel 250mg Capsule 30'S
Prescription Required
Salt Composition : Trientine Hydrochloride
Manufacturer : MSN LABORATORIES (INDIA)
Origin of Medicine : India
30 Capsule(s) In A Bottle
Introduction to Cuchel 250mg Capsule 30's
Cuchel Capsule contains the active constituent Trientine hydrochloride. It is a copper chelator used to treat adult patients with stable Wilson’s disease who cannot tolerate any medicine used to treat this disease. Wilson’s disease is an inherited condition in which the body cannot transport copper around the body in normal ways or remove copper normally as a secretion from the liver into the gut. This means that the small amounts of copper from food and drink build up to excessive levels and can lead to liver damage and problems in the nervous system.
This medicine mainly works by attaching to copper in the body, allowing it to be removed in the urine instead, helping to lower copper levels. It may also attach to copper in the gut and reduce the amount taken into the body. Do not take this medicine if you are allergic to Trientine hydrochloride or any other ingredients in this medicine. Cuchel Capsules may also reduce the iron level in your blood; you may be prescribed iron supplements. Inform your physician if you have kidney or liver problems, breathing problems, dermatitis (red and itchy skin), anaemia or if you're pregnant or breastfeeding.
Uses of Cuchel 250mg Capsule 30's
- Wilson’s disease
Therapeutic Effects of Cuchel 250mg Capsule 30's
Cuchel Capsule is a copper chelating agent that binds excess copper in the body and assists in elimination from the body. It may also work by attaching to the copper in your stomach and stopping it from being absorbed.
Interaction of Cuchel 250mg Capsule 30's with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications may interact with Cuchel Capsule and reduce its effectiveness by causing undesirable side effects.
More Information about Cuchel 250mg Capsule 30's
- Store this Cuchel Capsule at room temperature 20°C to 25°C
- Keep the medicine out of reach of children and pets
- If you forgot to take the tablet, simply take your next dose at the scheduled time. Do not take a double dose to make up for a forgotten dose.
How to consume Cuchel 250mg Capsule 30's
Your doctor will decide the dose and duration of Cuchel Capsule based on the disease condition and other factors. Always take this medicine as prescribed by your doctor. Swallow the capsules with water on an empty stomach (at least one hour before meals or two hours after meals, and at least one hour apart from any other medicines, food, or milk.) Do not break, chew, crush, or break the tablet.
Safety Advices for Cuchel 250mg Capsule 30's
Pregnancy
Do not take Cuchel Capsule if you are pregnant because this may harm the unborn baby. Inform your physician if you are pregnant, suspecting pregnancy, or planning to get pregnant during the treatment.
Breast Feeding
Breastfeeding is not recommended in patients taking Cuchel Capsule because the medicine passes into the breast milk in small amounts and may harm your baby.
Lungs
It is unknown whether Cuchel Capsule can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
Liver
It is unknown whether Cuchel Capsule can be used in patients with liver disorders. Consult your doctor if you have any liver diseases before starting the treatment.
Alcohol
It is unknown whether consuming alcohol is safe when taking Cuchel Capsule. Inform your physician if you are an alcoholic before starting the treatment.
Driving
Cuchel Capsule does not affect the ability to drive or operate heavy machinery. If you feel dizzy after taking the medicine. Consult your doctor for more advice.
Side Effects of Cuchel 250mg Capsule 30's
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Common
- Abdominal pain
- Change of bowel movements
- Rash
- Alopecia
- Mood swings
- Difficulty in moving
- Muscle pain
Serious
- Iron deficiency anemia
- Hypersensitivity skin reactions
Word of Advice
Avoid concomitant use of mineral supplements like iron, zinc, calcium, and magnesium. Consult your physician before taking any vitamin or mineral supplements. Take this medicine at least 2 hours before or 2 hours after taking iron supplements or 1 hour before or 2 hours after taking other supplements like calcium, magnesium, or zinc. This medicine may cause copper or iron deficiency. Your doctor will do lab tests at regular visits to check on the effects of this medicine.
FAQs
Q 1. Can I receive vaccination while taking Cuchel Capsule?
Limited data on vaccination use during Cuchel Capsule therapy is available. Consult your doctor before receiving any vaccines.
Q 2. What is the difference between Cuchel Capsule and penicillamine?
Penicillamine is used therapeutically to re-establish copper balance, trientine is indicated for patients with penicillamine intolerance. Your doctor will decide which medicine works best for you.
Q 3. Can I take vitamin or mineral supplements with a Cuchel Capsule?
Avoid taking supplements concomitantly with the Cuchel Capsule. Take this medicine at least 2 hours before or after taking vitamin or mineral supplements.
Q 4. Will Cuchel Capsule increase the body temperature?
The patient should check their body temperature each night during the first month of therapy and report the occurrence of fever.
Q 5. What is Cuchel Capsule used to treat?
Cuchel Capsule is an orally available copper-chelating agent that is used to treat Wilson disease, an inherited abnormality of copper metabolism that leads to excess copper accumulation and injury to the liver and brain.
Fact Box of Cuchel 250mg Capsule 30's
Molecule name: Trientine hydrochloride | Therapeutic class: Copper Chelators |
Pharmacological class: Chelating Agents | Indications: To treat Wilson’s disease |
References
- Trientine dihydrochloride Tillomed 250 mg capsules, hard - Summary of Product Characteristics (SmPC) - (emc). www.medicines.org.uk. [cited 2023 Apr 3]. Available from: https://www.medicines.org.uk/emc/product/11626/smpc
- HIGHLIGHTS OF PRESCRIBING INFORMATION. Food and Drug Administration - Cuchel 250mg Capsule 30'S. [revised on 2022] [cited 2023 Apr 3]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/215760s000lbl.pdf
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Environmental toxicology: Carcinogenesis and Heavy metals, 12th edition, 2011, 1875.
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