CYTAX 260MG INJECTION

Introduction:

Cytax 260mg Injection is a chemotherapy medication containing the active constituent paclitaxel. It is used to treat breast cancer, non-small cell lung cancer, ovarian cancer, and AIDS (Acquired Immuno-Deficiency Syndrome) related Kaposi’s sarcoma. This medication may also be used to treat cancers in the cervix, bladder, skin, and esophagus. Cancer is a condition in which cells are dividing and growing fast and in an uncontrolled manner. This medicine is not recommended for adolescents and children under the age of 18.

Cytax 260mg Injection may be given alone or in combination with other anticancer medicines. This chemotherapy medication is contraindicated in patients with severe liver problems, uncontrolled infection, and low white blood cell or platelet count. Talk to your doctor if you have heart disorders before taking this medicine.

Administration of this medicine may cause serious allergic reactions. Use effective birth control during the treatment and for at least six months after the last dose. Cytax 260mg Injection may be harmful to the patients suffering from alcoholism as this medicine contains alcohol.

Uses of Cytax 260mg Injection:

• Cancers in the breast, ovary, bladder, cervix, skin, and esophagus
• Non-small cell lung cancer
• AIDS-related Kaposi’s sarcoma

How Cytax 260mg Injection works:

Cytax 260mg Injection inhibits the microtubule structures present in the cell. Microtubule structures help cancer cells to divide and multiply. Inhibition of these structures slows the growth of cancer cells.

Interactions with other drugs:

Inform your doctor about any medications you are taking or have taken before the treatment.

More information:

• Keep Cytax 260mg Injection out of sight and reach of children.
• Store at controlled room temperature between 20°C to 25°C.

References:

1. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Cytotoxic agents, 12th edition, 2011, 1707 - 1709.
2. KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 865.
3. Hospira UK Limited, Electronic medicines compendium (emc), [ Revised on March 2020] [ Accessed on 22nd June 2021], https://www.medicines.org.uk/emc/files/pil.3891.pdf
4. Bristol-Myers Squibb Company, US Food and Drug Administration, [ Revised on April 2011] [ Accessed on 22nd June 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/020262s049lbl.pdf
5. Spyridon Sideris et al; Efficacy of weekly paclitaxel treatment as a single agent chemotherapy following first-line cisplatin treatment in urothelial bladder cancer; Molecular and Clinical Oncology; Published on 17/03/2016; Accessed on 26/05/2022; https://www.spandidos-publications.com/10.3892/mco.2016.821
6. Hiroko Machida et al; Efficacy of Modified Dose-dense Paclitaxel in Recurrent Cervical Cancer; American Journal of Clinical Oncology; Published on 01/10/2020; Accessed on 26/05/2022; https://pubmed.ncbi.nlm.nih.gov/28763329
7. Dashan Ai MD et al; Comparison of 3 Paclitaxel-Based Chemoradiotherapy Regimens for Patients With Locally Advanced Esophageal Squamous Cell Cancer A Randomized Clinical Trial; JAMA; Published on 21/02/2022; Accessed on 26/05/2022; https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2789153
8. Linyan Zhu, Liqun Chen; Progress in research on paclitaxel and tumor immunotherapy; Cellular & Molecular Letters; Published on 13/06/2019; Accessed on 26/05/2022; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567594/

How to use Cytax 260mg Injection:

It will be given to you by a doctor or nurse. 

Safety advice:

Pregnancy:

Cytax 260mg Injection can harm your unborn baby. Tell your doctor if you are pregnant or planning to get pregnant before taking this medication. 

Breastfeeding:

Stop breastfeeding during the treatment with Cytax 260mg Injection. Consult your doctor for potential risks.

Liver:

It is contraindicated in patients with severe liver disorders. Inform your doctor if you have any liver disorders before taking Cytax 260mg Injection.

Driving: 

The alcohol present in Cytax 260mg Injection may affect your ability to drive. Avoid driving if you feel unwell.

Others:

• Inform your doctor if you have heart disorders, uncontrolled infection, or alcohol addiction.

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.

Serious:

• Serious allergic reactions (rash, swelling of face, lips, throat, or tongue, trouble breathing, and swallowing)
• Severe diarrhea
• Severe stomach pain

Common:

• Anemia, feeling tired
• Hair loss
• Burning, tingling, or numbness in your feet or hands
• Muscle and joint pain
• Vomiting, nausea
• Mouth or lip sores
• Infections
• Swelling of hands, feet, and face
• Bleeding
• Irritation at the injection site
• Low blood pressure

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