Cytomab 100mg injection contains the active ingredient rituximab and is used to treat various conditions in adults. Cytomab 100mg can be administered alone or with other medications to manage non-Hodgkin’s lymphoma (a cancer affecting B-lymphocytes) and chronic lymphocytic leukemia (a common cancer of B-cells). It is also indicated for moderate-to-severe rheumatoid arthritis, in combination with methotrexate, in adults. Other uses include treating granulomatosis with polyangiitis or microscopic polyangiitis (inflammation of blood vessels affecting lungs and kidneys) in adults and children aged 2 years and older. Additionally, it is used for moderate-to-severe pemphigus vulgaris, an autoimmune condition causing painful blisters on the skin and mucous membranes.

Patients often inquire about Cytomab 100mg price, and healthcare providers may explain how Cytomab 100mg works—by targeting and depleting specific B-cells responsible for abnormal immune responses or cancer growth, thereby helping to control the disease

Cytomab 100mg uses are 

• Non-hodgkin’s lymphoma (NHL)
• Chronic lymphocytic leukemia (CLL)
• Rheumatoid Arthritis
• Granulomatosis with polyangiitis or microscopic polyangiitis
• Pemphigus vulgaris

Rituximab is a monoclonal antibody that targets the antigen CD20 expressed on the cell surface of B-lymphocytes (a type of white blood cell). When this medicine binds to the B-cell, it induces cell death. The binding action blocks cell activation and growth and causes anticancer effects. It inhibits rheumatoid factor (RF) production, antigen presentation, T-cell activation, and certain signalling molecules in rheumatoid arthritis. 

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. In particular, tell your doctor if you are taking medicines for blood pressure or other heart conditions. Certain medications may interact with Cytomab 100mg injection and reduce its effectiveness by causing undesirable side effects. 

• Store Cytomab 100mg injection  in the refrigerator (2°C to 8°C)
• Do not freeze
• Keep the injection away from the reach of children and pets.
• If you have missed any dosing appointments, inform your doctor and schedule immediately.

It should only be administered by a trained doctor or nurse. Do not self-administer the injection. Before giving Cytomab 100mg injection, you will be given other medications (pre-medication) to reduce the possible side effects. Your doctor will decide the dose and duration of your treatment based on the disease severity and other factors. It will be given as an intravenous infusion, and you will be monitored carefully for any unwanted side effects.  

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Cytomab 100mg side effects are

Common

• Swelling in the face and body
• Diarrhea and nausea
• Itchy skin
• Anemia
• Muscle spasm
• Headache
• Urinary tract infection
• Fever, chills, and shivering
• Inflammation of nasal cavities
• Cough, sore throat
• Loss of hair

Serious

• Increased or decreased blood pressure
• Chest pain
• Hypersensitivity reactions
• Hepatitis B viral infection
• Memory loss, trouble thinking, difficulty in walking

1. Highlights of prescribing information; rituximab, (2021). Available at: https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/103705s5464lbl.pdf  [Accessed 9 Mar. 2023].
2. Package leaflet, Rituximab. (Revised on 2020). Available at: https://www.ema.europa.eu/en/documents/product-information/mabthera-epar-product-information_en.pdf  [Accessed 9 Mar. 2023].
3. Ahmed A. Negm & Daniel E. Furst, Nonsteroidal Anti-Inflammatory Drugs, Disease-Modifying Antirheumatic Drugs, Nonopioid Analgesics, & Drugs Used in Gout, Lange's Basic & Clinical Pharmacology, 14th Edition, 2018, 642-666