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Dacilon 0.5mg Injection
Prescription Required
Salt Composition : Dactinomycin
Manufacturer : CELON LABORATORIES LTD
Origin of Medicine : India
1 Vial(s)
Introduction to Dacilon 0.5mg Injection
Dacilon 0.5mg Injection is an anti-cancer medication that contains Dactinomycin, also known as actinomycin D. It belongs to a class of drugs called antineoplastic antibiotics, commonly used in chemotherapy. This medicine is primarily used to treat specific types of cancer by slowing down or stopping the growth of cancer cells. Dactinomycin is typically given as an injection under the supervision of a trained healthcare professional.
Dacilon 0.5mg Injection is used in various cancer types such as Wilms’ tumour, rhabdomyosarcoma, Ewing’s sarcoma, and testicular cancer, among others. Though effective, it must be used cautiously in patients with liver issues or low blood counts. It is not recommended during pregnancy or while breastfeeding unless absolutely necessary. Patients undergoing this treatment need close medical monitoring due to the risk of side effects and drug interactions. Always inform your doctor about any ongoing medications or health conditions before starting therapy.
Uses of Dacilon 0.5mg Injection
Dacilon 0.5mg Injection is FDA-approved for the treatment of the following cancers:
- Wilms' tumour (kidney cancer in children)
- Rhabdomyosarcoma (soft tissue cancer)
- Ewing’s sarcoma (bone cancer)
- Gestational trophoblastic neoplasia (cancer linked to pregnancy)
- Testicular cancer (when combined with other chemotherapy drugs)
- Certain types of solid tumours in children
Therapeutic Effects of Dacilon 0.5mg Injection
Dactinomycin works by interfering with the DNA of cancer cells. It binds to their genetic material and prevents them from multiplying. When cancer cells can’t grow or divide, they eventually die. This helps to shrink tumours and slow down the spread of cancer. Since the drug targets rapidly dividing cells, it can also affect some healthy cells, which is why side effects may occur. However, its action makes it highly effective in stopping the progression of certain fast-growing cancers when used as prescribed by a cancer specialist.
Interaction of Dacilon 0.5mg Injection with other drugs
Dacilon 0.5mg Injection should not be taken alongside certain medications or in specific health conditions due to the risk of serious side effects. Always inform your doctor about all the medications you take, including prescription drugs, over-the-counter products, and herbal supplements.
- Combining with live vaccines (e.g., MMR, BCG) can increase the risk of serious infections because Dactinomycin suppresses the immune system.
- When used with radiation therapy, there’s an increased risk of skin and tissue damage.
- Avoid using with other bone marrow suppressants like doxorubicin, as it may lead to dangerously low blood counts.
- Drugs that affect the liver, such as phenytoin or methotrexate, may increase toxicity due to altered metabolism.
- Antibiotics like trimethoprim-sulfamethoxazole can worsen blood-related side effects.
These interactions may not be exhaustive. Therefore, any new symptoms or unusual reactions should be immediately reported to your healthcare provider. Use of this medicine requires regular blood tests and clinical monitoring to avoid complications.
More Information about Dacilon 0.5mg Injection
- Store in a refrigerator at 2°C – 8°C.
- Do not freeze.
- Inform your doctor if you miss a dose. Do not try to take a missed injection on your own.
- This medicine should only be handled by trained medical professionals in a clinical setting.
How to consume Dacilon 0.5mg Injection
Dacilon 0.5mg Injection is given as an intravenous (IV) injection under the supervision of a trained oncologist or nurse. The dosage and schedule depend on the type of cancer being treated, the patient’s weight, and overall health. It is not taken orally and should never be self-administered. There are no food restrictions linked directly to this medicine, but patients should follow any dietary advice given by their doctor during treatment.
Safety Advices for Dacilon 0.5mg Injection
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Pregnancy
 ÂDacilon 0.5mg Injection is not recommended during pregnancy as it may harm the developing baby. Women of childbearing age should use effective contraception during treatment.
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Breast Feeding
 ÂBreastfeeding during this Dacilon 0.5mg is unsafe. Depending on your condition, your physician might suggest you stop breastfeeding for some time.
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Lungs
 ÂInform your physician about any underlying lung disorders before taking Dacilon 0.5mg. Consult your physician before taking this medicine. Notify your doctor if you experience any lung-related symptoms, such as difficulty breathing or inflamed lungs.Â
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Liver
 ÂInform your physician about any underlying liver disorders before taking Dacilon 0.5mg, as this medication should be used cautiously in liver disease patients. Consult your physician before taking this medicine.
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Alcohol
 ÂAvoid alcohol while receiving Dacilon 0.5mg Injection as it may worsen side effects like nausea and liver problems.
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Driving
 ÂIt is unknown whether driving while taking a Dacilon 0.5mg injection alters driving ability. Do not drive if you experience any side effects.Â
Side Effects of Dacilon 0.5mg Injection
Common Side Effects
- Nausea or vomiting
- Hair loss (temporary)
- Mouth sores
- Diarrhea
- Fatigue
- Skin peeling or redness at the injection site
Serious Side Effects
- Severe infection due to low white blood cell count
- Liver damage (yellowing of eyes/skin)
- Unusual bleeding or bruising
- Trouble breathing or chest pain
- Swelling or pain at the injection site
Word of Advice
Dacilon 0.5mg Injection is a powerful chemotherapy drug and should only be taken under close medical supervision. During treatment, it is important to maintain good hygiene and avoid crowded places to reduce infection risk due to a weakened immune system. Patients are advised to follow up regularly for blood tests and liver function monitoring. Report any signs of fever, unusual tiredness, or bleeding to your doctor immediately. Avoid self-medicating or taking any other drug without your oncologist's approval during the course of therapy.
FAQs
Q 1. Why do I feel numbness and tingling while taking Dacilon 0.5mg?
Dacilon 0.5mg can damage these nerves, leading to numbness, tingling, or a burning sensation in the hands and feet. If you are experiencing this while taking this treatment, it is important to inform your doctor.
Q 2. How is Dacilon 0.5mg dosage determined?
Dacilon 0.5mg dosage is based on several factors, including the type and stage of the cancer being treated, the individual's overall health, and their response to the treatment.
Q 3. What is the precaution for Dacilon 0.5mg?
Inform your doctor if you have any underlying medical conditions with kidney, liver, or bone marrow. Notify your doctor if you are pregnant or planning to get pregnant or breastfeeding.
Q 4. When should I use contraception? During or after the treatment of Dacilon 0.5mg?
It is advised to use during and after the treatment of Dacilon 0.5mg. Women should use six months; for men, it's three months after the last dose.
Q 5. Does Dacilon 0.5mg cause any side effects to the eyes?
Blurring eyes is one of the most common side effects of eyes with Dacilon 0.5mg. If you experience any side effects, contact your doctor immediately.
Fact Box of Dacilon 0.5mg Injection
Molecule name: Dactinomycin  | Therapeutic class: Antineoplastics |
Pharmacological class: Antibiotics | Indications: 1. Ewing’ sarcoma (bone cancer) 2. Rhabdomyosarcoma (muscle cancer) 3. Melanoma (skin cancer) 4. Wilms’ tumor (kidney cancer usually appears in children) 5. Testicular and uterus cancer |
References
Disclaimer
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