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Darberel 40mcg Injection

Prescription Required
Cold Chain Required
darbepoetin alfa

1401

MRP: 2798

(You Save ₹1397)

1 PREFILLED SYRINGE(s) OF 0.40ML

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Darberel 40mcg Injection
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1401

MRP: 2,798.00

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50% Off

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1 Prefille...

1 Prefilled Syringe(s) Of 0.40ml

1401.0/Unit
Prescription Required
Prescription Required
Cold Chain Required
Cold Chain
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Salt Composition

DARBEPOETIN ALFA

Marketer

RELIANCE LIFE SCIENCES PVT LTD

Prepaid Only. Non-Returnable.

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Introduction

Darberel 40mcg Injection contains the active ingredient Darbepoetin Alfa, a hematopoietic growth factor used to treat anemia (low red blood cell count) in patients with chronic kidney disease or anemia resulting from chemotherapy in certain cancers. It works by stimulating the bone marrow to produce more red blood cells, thereby improving oxygen delivery throughout the body.

The Darberel 40mcg Injection dosage is determined by your doctor based on your medical condition and hemoglobin levels. It is administered subcutaneously or intravenously under medical supervision. Patients trained in the correct Darberel 40mcg Injection administration technique may also use it at home after receiving proper guidance.

For best results, store the medicine as per the Darberel 40mcg Injection storage instructions — usually in a refrigerator between 2°C and 8°C, away from light and freezing conditions.

Patients can Buy Darberel 40mcg Injection online through verified pharmacies. The Darberel 40mcg Injection price may vary depending on the brand and quantity. Your doctor may recommend Darberel 40mcg Injection substitutes if suitable alternatives are available.

Consult your physician before use if you are pregnant or planning pregnancy (Darberel 40mcg Injection and pregnancy) or if you are breastfeeding (Darberel 40mcg Injection and breastfeeding) to ensure safe treatment.

Uses

Darberel 40mcg Injection uses are 

  • To treat anemia in chronic kidney failure
  • To treat anemia caused by chemotherapy

How Darberel 40mcg Injection works

Darberel Injection (Darberel 40mcg Injection) is an erythropoiesis-stimulating protein produced using recombinant DNA technology. It is closely related to erythropoietin and works by the same mechanism—stimulating erythropoiesis, the process of red blood cell formation. Both agents bind to progenitor stem cells in the bone marrow, encouraging the production and differentiation of red blood cells. Darberel injection helps increase red blood cell count by prompting the bone marrow to produce more, making it effective in treating anemia associated with chronic kidney disease or chemotherapy.

Interaction of Darberel 40mcg Injection with other drugs

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications may interact with Darberel 40mcg Injection and reduce its effectiveness by causing undesirable side effects. 

Storage conditions

  • Store in a refrigerator (2°C to 8°C).
  • Do not freeze. Store in the original package to protect from light.
  • Keep the injection away from the reach of children and pets.
  • If you have missed any dosing appointments, inform your doctor and schedule immediately.

How to use Darberel 40mcg Injection

This injection is to be given under the skin (subcutaneous). Your doctor, nurse, or other healthcare professional will train you on how to inject yourself with this pre-filled pen. Do not try to inject the pre-filled pen if you are not well-trained. Never inject the medicine into your vein. If you need help to inject the medicine, visit the nearby hospital or clinic

Safety Advice for Darberel 40mcg Injection

Breast Feeding-unsafe

Breast Feeding

Unsafe

Breastfeeding is not recommended in patients taking Darberel 40mcg Injection because the medicine passes into the breast milk in small amounts and may harm your baby.  

Alcohol-Consult your doctor

Alcohol

Consult Your Doctor

It is unknown whether consuming alcohol is safe during the treatment with Darberel 40mcg Injection. Inform your doctor if you are a chronic drinker.  

Liver-Consult your doctor

Liver

Consult Your Doctor

Darberel 40mcg Injection is unsafe to administer in patients with liver problems. Dose adjustments are necessary. Inform your physician if you have any liver diseases or problems before initiating the therapy.   

Lungs-Consult your doctor

Lungs

Consult Your Doctor

It is unknown whether Zynesp 25mcg epoetin injection can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.  

Driving-safe

Driving

Safe

Darberel 40mcg Injection will not make you feel tired, dizzy, or sleepy. It is safe to drive or operate heavy machinery after taking this medicine. 

Pregnancy-Consult your doctor

Pregnancy

Consult Your Doctor

There are no adequate and well-controlled studies on the use of Darberel 40mcg Injection in pregnant women. Inform your physician if you are pregnant, suspecting, or planning for pregnancy during the treatment.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Darberel 40mcg Injection side effects are 

 Common 

  • Swelling in the face and body
  • Low blood pressure
  • Abdominal pain
  • Shortness of breath
  • cough

Serious

  • Heart problems
  • Severe skin reactions
  • Anemia
  • Seizure attack
  • Lung problems

Expert Tips

  • Follow your doctor’s instructions carefully regarding the exact dose and frequency of administration.

  • This medicine is given as a subcutaneous injection (a shot under the skin).

  • A nurse or healthcare professional will usually administer the injection, but you may be trained to use it at home.

  • Understand all instructions thoroughly before giving yourself the injection.

  • Do not exceed the prescribed dose or use the medicine more frequently than directed by your doctor.

  • Do not shake the vial or syringe before use.

  • You will be advised on the specific body areas suitable for injection.

  • Rotate injection sites: use a different area each time to prevent irritation or tissue damage.

  • Keep a record of injection sites to ensure proper rotation.

  • Inform your doctor if you are pregnant or breastfeeding.

  • Also, tell your doctor if you have kidney or heart disease, heart failure, blood disorders, infections, cancer, or a history of blood clots, heart attack, stroke, or seizures.

FAQs about Darberel 40mcg Injection

Q1.

Can Darberel 40mcg Injection be used in patients with kidney failure who are undergoing dialysis? 

Yes, Darberel 40mcg Injection is commonly used in patients with kidney failure who are undergoing dialysis to manage anemia.

Q2.

Can Darberel 40mcg Injection be used in patients with a history of heart disease?

Darberel 40mcg Injection should be used with caution in patients with a history of heart disease, as it may increase the risk of certain cardiovascular events. It is crucial to discuss the potential risks and benefits with a healthcare provider before initiating treatment.

Q3.

Can Darberel 40mcg Injection be used to treat anemia caused by nutritional deficiencies?

Darberel 40mcg Injection is not typically used to treat anemia caused by nutritional deficiencies. It is primarily used for anemia related to chronic kidney disease, cancer chemotherapy, and other specific conditions. Nutritional deficiencies require appropriate dietary changes and/or supplementation.

Q4.

Can Darberel 40mcg Injection be used to treat anemia in patients undergoing radiation therapy?

Darberel 40mcg Injection is used to treat anemia in patients undergoing chemotherapy, depending on the specific circumstances and the healthcare provider's recommendation. The anemia is typically managed through a comprehensive treatment plan determined by the oncology team.

Q5.

Can Darberel 40mcg Injection interact with other medications?

Darberel 40mcg Injection may interact with certain medications, such as blood thinners or immunosuppressants. It is important to inform the healthcare provider about all medications, including over-the-counter drugs and supplements, to avoid potential interactions or adverse effects.

Fact Box of Darberel 40mcg Injection

  Molecule name

Darbepoetin Alfa

Therapeutic class

Antineoplastics

Pharmacological class

Hematopoietic growth Factors

 Indications

1.To treat anemia in chronic kidney failure 

2.To treat anemia caused by chemotherapy 

References

  1. Aranesp solution for injection in pre-filled pen (SureClick) - Summary of Product Characteristics (SmPC) - (emc). www.medicines.org.uk. Published March 2022. Accessed May 10, 2023. http://www.medicines.org.uk/emc/product/6958/smpc
  2. Darbepoetin Alfa.; Revised June 2011. Accessed May 10, 2023. https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/103951orig1s5173_103951orig1s5258lbl.pdf
  3. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Hematopoietic agents, 12th edition, 1071 - 1072.
  4. KD Tripathi, Essentials of Medical Pharmacology, Haematinics and Erythropoietin, 7th edition, 2013, 611.

Disclaimer

MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.

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