Quick Summary
Debrumab 60mg Injection
Last updated on 14 May 2026 | 08:45 AM (IST)
₹5508
MRP: ₹22031.25
(You Save ₹16523.25)
1 PREFILLED SYRINGE(s) OF 1ML
Debrumab 60mg Injection contains denosumab, a monoclonal antibody used to treat osteoporosis and bone loss associated with certain cancers. It works by inhibiting osteoclast activity, reducing bone resorption and fracture risk. The injection is administered subcutaneously under medical supervision.
Debrumab 60mg Injection
Salt Composition
DENOSUMABMarketer
RPG LIFE SCIENCES LTD
Prepaid Only. Non-Returnable.
75% OFF
₹5508
MRP: ₹22,031.25
Inclusive of all taxes
75% Off
Salt Composition
DENOSUMABMarketer
RPG LIFE SCIENCES LTD
Prepaid Only. Non-Returnable.
Dispatch: Today
Order In: 0h 0m 0s
0h 0m 0s
Order before timer ends to ensure your medicine is dispatched at...
Substitutes
Olimab 60mg Injection
INTAS PHARMACEU...
₹ 6647.00/
21% costlier
Denub 60mg Injection
ALKEM LABORATOR...
₹ 6469.00/injection
18% costlier
Denuril 60mg Injection
ALKEM LABORATOR...
₹ 6469.00/injection
18% costlier
Denu 60mg Injection
ALKEM LABORATOR...
₹ 6469.00/injection
18% costlier


Introduction
Debrumab 60mg Injection contains the active ingredient Denosumab, a monoclonal antibody used to treat osteoporosis, a condition characterized by weakened bones and increased fracture risk. It is also prescribed to prevent skeletal complications in patients with multiple myeloma or bone metastases from solid tumors.
This medication works by inhibiting a protein called RANK ligand, which is responsible for bone resorption (breakdown). By blocking this pathway, Debrumab helps strengthen bone density and reduce the risk of fractures in postmenopausal women and cancer patients experiencing bone loss.
Patients are advised to follow the recommended Debrumab 60 mg dosage as directed by their physician. Regular monitoring of calcium levels and renal function is essential, especially for individuals with moderate kidney impairment.
If you’re considering treatment options, you can compare Debrumab vs Prolia, as both contain Denosumab but may differ in formulation and dosing frequency.
Those looking for affordability and convenience can check the Debrumab 60mg injection price or buy Debrumab online India through certified medical platforms that ensure genuine and cold-chain-protected products. For patients seeking alternatives, various Debrumab alternatives are available, depending on clinical suitability and prescription.
The Debrumab injection cost per injection may vary depending on the pharmacy, manufacturer, and location. Like any medication, possible Debrumab injection side effects include fatigue, back pain, low calcium levels, and, rarely, jaw osteonecrosis, hence regular dental care is recommended.
Close follow-up with your healthcare provider ensures optimal safety and efficacy during treatment.
Uses
Debrumab 60 mg uses are
- Osteoporosis
- Bone loss due to hormonal therapy in breast or prostate cancer
- Multiple myeloma (cancer affects plasma cells in the bone marrow)
- Bone metastases (cancer that spreads to bone)
How Debrumab 60mg Injection works
Denosumab has therapeutic effects that include reducing fracture risk, increasing bone mineral density, and improving overall bone health. By inhibiting bone resorption through its action on RANK ligands, this medication helps to strengthen bones and decrease the likelihood of fractures in individuals with osteoporosis or those at high risk. It also increases bone mineral density, an important marker of bone strength. These therapeutic effects contribute to improved bone health and a reduced risk of fractures, ultimately enhancing the quality of life for patients.
Interaction of Debrumab 60mg Injection with other drugs
Inform the doctor about all the medicines, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Debrumab 60mg Injection and reduce effectiveness by causing undesirable side effects.
Storage conditions
- Debrumab 60mg Injection should be stored in the refrigerator at a temperature between 2°C to 8°C (36°F to 46°F).
- Do not freeze it.
- Keep in the original package.
- Keep away from light, moisture, and heat.
- Keep away from children and pets.
- Avoid taking double doses for missed doses.
How to use Debrumab 60mg Injection
Debrumab 60mg Injection is given as an injection by healthcare professionals. The dosage and duration of treatment will be based on the individual's condition and response to the medication and should be determined by a healthcare provider.
Safety Advice for Debrumab 60mg Injection
Breast Feeding
Whether Debrumab 60mg Injection is excreted in milk is unknown. So it is better to consult a healthcare provider if you are a breastfeeding mother before taking this medication.
Alcohol
It is generally recommended to avoid or limit alcohol consumption while taking Debrumab 60mg Injection. Alcohol can interact with this medication, potentially increasing the risk of side effects.
Liver
Debrumab 60mg Injection is primarily metabolized in the liver, and its safety has not been extensively studied in individuals with severe liver impairment. It is crucial to communicate any pre-existing liver conditions or changes in liver function to your healthcare provider to ensure this medication's safe and effective use.
Lungs
If you have a lung or respiratory disorders history, it is important to consult your healthcare provider before taking Debrumab 60mg Injection.
Driving
Patients receiving Debrumab 60mg Injection should be advised to avoid driving or operating machinery if they experience side effects such as fatigue, dizziness, or blurred vision, impairing a patient's ability to drive or operate machinery safely.
Pregnancy
The safety of using Debrumab 60mg Injection during pregnancy has not been established. Limited studies are available regarding the use of this medication in pregnant women, so it is recommended to use caution and consult a doctor before considering its use during pregnancy.
Side Effects
Debrumab 60mg Injection can cause side effects like all medications, although not everyone who takes it will experience them. Debrumab side effects are
Serious:
- Osteonecrosis of the jaw (severe necrosis or death of jaw cells)
- Atypical femoral fractures
- Hypocalcemia (low blood calcium levels)
Common:
- Injection site reactions
- Back pain
- Musculoskeletal pain
- Infections
- Abdominal pain
- Headache
- Hypophosphatemia (low blood phosphate levels)
Expert tips
-
Attend all scheduled appointments and follow-up visits to monitor treatment progress and manage any side effects.
-
Inform your doctor about your complete medical history, especially any past infections, liver disease, or kidney disease.
-
Notify your healthcare provider if you have any known allergies or hypersensitivity reactions.
-
Seek immediate medical attention if you experience severe allergic reactions or other serious side effects.
-
This medication may affect calcium levels — regular monitoring and adequate intake of calcium and vitamin D are important.
-
Pregnant and breastfeeding women should always consult their doctor before using this medication.
-
Avoid receiving any vaccines during treatment unless approved by your doctor.
-
Maintain good oral hygiene and attend regular dental check-ups to reduce the risk of jaw osteonecrosis.
FAQs about Debrumab 60mg Injection
Q1.
Can Debrumab 60mg Injection be used in patients with a history of cancer?
Debrumab 60mg Injection is not recommended in patients with a history of certain cancers, such as multiple myeloma or bone metastases. It is important to discuss your medical history and any previous or current cancer diagnoses with your healthcare provider before starting this medication.
Q2.
Can Debrumab 60mg Injection be used in patients with kidney problems?
Debrumab 60mg Injection is primarily eliminated through the kidneys, so caution is advised in patients with severe renal impairment or end-stage renal disease. Your healthcare provider will assess the potential risks and benefits based on your renal function.
Q3.
Can Debrumab 60mg Injection be used as a treatment for osteoporosis in men?
Yes, Debrumab 60mg Injection is approved for the treatment of osteoporosis in men at increased risk of fractures. It can help improve bone density and reduce fracture risk in male patients with osteoporosis.
Q4.
Can Debrumab 60mg Injection be used in children and adolescents with osteoporosis?
Debrumab 60mg Injection is not approved for use in children and adolescents with osteoporosis. The safety and efficacy of this medication have not been established in this population.
Q5.
Can Debrumab 60mg Injection be used in individuals with dental implants?
Debrumab 60mg Injection use has been associated with a slightly increased risk of jaw osteonecrosis (ONJ). Suppose you have dental implants or are considering getting them. In that case, it is important to discuss this with your dentist and healthcare provider to assess Debrumab 60mg Injection's potential risks and benefits.
Q6.
What Are the Side Effects of Debrumab 60mg Injection?
Debrumab 60mg Injection can cause side effects like injection site reactions, back and musculoskeletal pain, infections, abdominal pain, headache, and low blood phosphate levels. Rare but serious side effects may include osteonecrosis of the jaw, atypical femoral fractures, hypocalcemia, and severe skin reactions.
Fact Box of Debrumab 60mg Injection
|
Molecule name
|
Denosumab |
|
Therapeutic class |
Anti-resorptive agent |
|
Pharmacological class |
Monoclonal Antibodies |
| Indications |
1. Osteoporosis 2. Bone loss due to hormonal therapy in breast or prostate cancer 3. Multiple myeloma 4. Bone metastases |
References
- Amgen Ltd, Electronic medicines compendium (EMC), [ Revised on 13th May 2023], [ Accessed on 31st May 2023],https://www.medicines.org.uk/emc/files/pil.568.pdf
- Amgen Manufacturing Limited, US Food and Drug Administration, [ Revised on November 2010] [ Accessed on 31st May 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/125320s007lbl.pdf
- Amgen Manufacturing Limited, US Food and Drug Administration, [ Revised on November 2022] [ Accessed on 31st May 2023], https://www.fda.gov/media/163378/download
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
Did you find this information helpful?
Author Details

Written By
Dr. Vijayalakshmi N.
BDS

Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 14 May 2026 | 08:45 AM (IST)

Want to know more?
Read Our Editorial Policy
.jpg)






