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Deghor 80mg Injection
Salt Composition : Degarelix
Manufacturer : GLENMARK PHARMACEUTICALS LTD
Origin of Medicine : India
Introduction to Deghor 80mg Injection
Deghor 80mg injection contains the active ingredient degarelix. It is used to treat advanced prostate cancer. Prostate cancer is cancer that occurs in the prostate (a gland in males that produces seminal fluid). Cancer is a disorder in which cells multiply in an uncontrolled and abnormal manner.
Contact your doctor immediately if you experience dizziness, fever, or infection. During this treatment, your doctor may periodically monitor your blood pressure, blood sugar, electrolytes, heart, liver, and kidney parameters to prevent serious complications. Report to your doctor if you have been diagnosed with problems in your heart, liver, or kidneys. Patients with severe liver and kidney impairment should exercise caution while using this medicine. This medicine is contraindicated in patients with known hypersensitivity to this drug or to any of the product components.
Deghor 80mg injection has the potential to impair the fertility of males and females of reproductive potential. This injection is not recommended during pregnancy due to its ability to harm the foetus and cause miscarriage. It is not known if this medicine passes into breast milk. Consult your doctor for more advice. Possible side effects related to therapy include redness, swelling, and itching at the injection site. These are usually mild, self-limiting, and decrease within three days.
Uses of Deghor 80mg Injection
- Advanced prostate cancer
Therapeutic Effects of Deghor 80mg Injection
Deghor 80mg injection directly blocks the effects of a natural hormone (gonadotropin-releasing hormone, GnRH), reduces the level of the male hormone testosterone, and slows down the growth of prostate cancer cells.
Interaction of Deghor 80mg Injection with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Deghor 80mg injection and reduce effectiveness by causing undesirable side effects.
More Information about Deghor 80mg Injection
- Store Deghor 80mg injection in a refrigerator (2°C – 8°C).
- Do not freeze.
- Keep it out of reach from children and pets.
How to consume Deghor 80mg Injection
Deghor 80mg injection is available as a prefilled syringe and solution for injection. Your doctor or nurse will administer the injection into the fatty tissues just under your skin (subcutaneously). The dose, route of administration, and frequency will be decided by your doctor based on your disease condition and other factors.
Safety Advices for Deghor 80mg Injection
Deghor 80mg injection is unsafe when administered during pregnancy because it may cause birth defects in your baby. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.
It is not known whether Deghor 80mg injection passes into the breastmilk. Consult your doctor for more advice.
It is unknown whether Deghor 80mg injection can be administered to patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.
It is unknown whether Deghor 80mg injection can be administered in patients with liver disorders. Inform your physician if you have any liver problems before starting treatment with this Injection.
It is unsafe to consume alcohol with Deghor 80mg injection. Please consult your doctor for more advice.
It is unsafe to travel, drive vehicles, or operate heavy machinery after taking (1 hour) Deghor 80mg injection. Please consult your doctor.
Side Effects of Deghor 80mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
- Hot flashes
- Injection site reactions (redness and pain)
- Fever, chills
- Headache, dizziness
- Trouble sleeping
- Nausea, diarrhea
- Increased weight
- Excessive sweating (including night sweats)
- Muscle pain and discomfort
- Breast swelling, reduced size of testicles
- Decreased sex drive
Word of Advice
Deghor 80mg injection can cause hot flashes, hence it is advised to wear loose-fitting clothes to avoid discomfort. Eat a well-balanced diet. If you feel dizzy or tired, avoid driving or handling machines. Do not touch or rub your skin after injecting this medicine.
Q 1. Is Deghor 80mg injection used as a monotherapy to treat cancer?
Deghor 80mg injection is prescribed alone and also with other anti-androgen medications to treat hormonal cancer.
Q 2. Is it safe to use Deghor 80mg injection during pregnancy?
Deghor 80mg injection can harm an unborn baby and result in miscarriage. Hence it is not recommended during pregnancy.
Q 3. How is Deghor 80mg injection administered?
Deghor 80mg injection is administered as a subcutaneous injection (under the skin), usually in the lower abdomen, once every 28 days.
Q 4. What are the common side effects of Deghor 80mg injection?
Injection site reactions, weight gain, chills, hot flashes, hypertension, asthenia, tiredness, fever, constipation, back pain, urinary tract infection, changes in liver enzymes, dizziness, headache, and insomnia are the most common side effects of Deghor 80mg injection.
Q 5. Who should not take Deghor 80mg injection?
Deghor 80mg injection is not recommended for men who have a history of severe allergic reactions to the medication.
Fact Box of Deghor 80mg Injection
Molecule name: Degarelix
Therapeutic class: Antineoplastics
Pharmacological class: Gonadotropin-releasing hormone antagonists
Indications: Advanced prostate cancer
- Ferring Pharmaceuticals A/S, Electronic medicines compendium (EMC), [ Revised on Dec 2019] [ Accessed on 23rd March 2023], https://www.medicines.org.uk/emc/files/pil.6537.pdf
- Ferring Pharmaceuticals Inc, US Food and Drug Administration, [ Revised on Feb 2015] [ Accessed on 23rd March 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/022201s009lbl.pdf
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Natural products in cancer chemotherapy: Hormones and related agents, 12th edition, 2011, 1764.
- Claudine Isaacs, Anton Wellstein, and Anna T. Riegel, Hormones and Related Agents in the Therapy of Cancer, Goodman & Gilman’s Pharmacological Basis of Therapeutics, 13th Edition, 2018, 1237-1247.
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