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May cause hot flashes – Wear loose-fitting clothes to stay comfortable.
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Follow a balanced diet – Eat nutritious meals to support overall health.
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Avoid driving or operating machinery – Especially if you feel dizzy or tired.
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Do not touch or rub the injection site – Let the medicine absorb without interference.
Quick Summary
Segarelix 80mg Injection
Written By:Dr. Vijayalakshmi N.BDS Reviewed By:Dr. Tejashwin AdigaMBBS
Last updated on 01 Apr 2026 | 12:38 PM (IST)
₹12000
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Segarelix 80mg Injection
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Introduction
Segarelix 80mg Injection contains the active ingredient degarelix. It is used to treat advanced prostate cancer. Prostate cancer is cancer that occurs in the prostate (a gland in males that produces seminal fluid). Cancer is a disorder in which cells multiply in an uncontrolled and abnormal manner.
Contact your doctor immediately if you experience dizziness, fever, or infection. During this treatment, your doctor may periodically monitor your blood pressure, blood sugar, electrolytes, heart, liver, and kidney parameters to prevent serious complications. Report to your doctor if you have been diagnosed with problems in your heart, liver, or kidneys. Patients with severe liver and kidney impairment should exercise caution while using this medicine. This medicine is contraindicated in patients with known hypersensitivity to this drug or to any of the product components.
Segarelix 80 mg Injection has the potential to impair the fertility of males and females of reproductive potential. This injection is not recommended during pregnancy due to its ability to harm the foetus and cause miscarriage. It is not known if this medicine passes into breast milk. Consult your doctor for more advice. Possible side effects related to therapy include redness, swelling, and itching at the injection site. These are usually mild, self-limiting, and decrease within three days. Segarelix injection price is depends on the retailer and the Place.
Uses
Degarelix 80 mg injection used for:
- Advanced prostate cancer
How Segarelix 80mg Injection works
Degarelix directly blocks the effects of a natural hormone (gonadotropin-releasing hormone, GnRH), reduces the level of the male hormone testosterone, and slows down the growth of prostate cancer cells.
Interaction of Segarelix 80mg Injection with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Segarelix 80mg Injection and reduce its effectiveness by causing undesirable side effects.
Storage conditions
- Store Segarelix 80mg Injection in a refrigerator (2°C – 8°C).
- Do not freeze.
- Keep it out of reach from children and pets.
How to use Segarelix 80mg Injection
Segarelix 80mg Injection is available as a prefilled syringe and solution for injection. Your doctor or nurse will administer the injection into the fatty tissues just under your skin (subcutaneously). The dose, route of administration, and frequency will be decided by your doctor based on your disease condition and other factors.
Safety Advice for Segarelix 80mg Injection
Breast Feeding
Consult Your Doctor
It is not known whether Segarelix 80mg Injection passes into the breastmilk. Consult your doctor for more advice.
Alcohol
Unsafe
It is unsafe to consume alcohol with Segarelix 80mg Injection. Please consult your doctor for more advice.
Liver
Consult Your Doctor
It is unknown whether Segarelix 80mg Injection can be administered in patients with liver disorders. Inform your physician if you have any liver problems before starting treatment with this Injection.
Lungs
Consult Your Doctor
It is unknown whether Segarelix 80mg Injection can be administered to patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.
Driving
Unsafe
It is unsafe to travel, drive vehicles, or operate heavy machinery after taking (1 hour) Segarelix 80mg Injection. Please consult your doctor.
Pregnancy
Unsafe
Segarelix 80mg Injection is unsafe when administered during pregnancy because it may cause birth defects in your baby. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.
Side Effects
Segarelix 80 mg injection side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Common
- Hot flashes
- Injection site reactions (redness and pain)
- Fever, chills
- Headache, dizziness
- Trouble sleeping
- Tiredness
- Nausea, diarrhoea
- Increased weight
- Excessive sweating (including night sweats)
- Anemia
- Muscle pain and discomfort
- Breast swelling, reduced size of testicles
- Decreased sex drive
Expert Tips
FAQs about Segarelix 80mg Injection
Q1.
Is Segarelix 80mg Injection used as a monotherapy to treat cancer?
Segarelix 80mg Injection is prescribed alone and also with other anti-androgen medications to treat hormonal cancer.
Q2.
Is it safe to use Segarelix 80mg Injection during pregnancy?
Segarelix 80mg Injection can harm an unborn baby and result in miscarriage. Hence it is not recommended during pregnancy.
Q3.
What is the correct way to take Segarelix 80mg Injection?
Segarelix 80mg Injection is administered as a subcutaneous injection (under the skin), usually in the lower abdomen, once every 28 days.
Q4.
What are the common side effects of Segarelix 80mg Injection?
Injection site reactions, weight gain, chills, hot flashes, hypertension, asthenia, tiredness, fever, constipation, back pain, urinary tract infection, changes in liver enzymes, dizziness, headache, and insomnia are the most common side effects of Segarelix 80mg Injection.
Q5.
Who should not take Segarelix 80mg Injection?
Segarelix 80mg Injection is not recommended for men who have a history of severe allergic reactions to the medication.
Fact Box of Segarelix 80mg Injection
| Molecule name | Degarelix |
| Therapeutic class |
Gonadotropin-Releasing Hormone (GnRH) Antagonists |
| Pharmacological class |
Gonadotropin-releasing hormone antagonists |
| Indications: |
Advanced prostate cancer |
References
- Ferring Pharmaceuticals A/S, Electronic medicines compendium (EMC), [ Revised on Dec 2019] [ Accessed on 23rd March 2023], https://www.medicines.org.uk/emc/files/pil.6537.pdf
- Ferring Pharmaceuticals Inc, US Food and Drug Administration, [ Revised on Feb 2015] [ Accessed on 23rd March 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/022201s009lbl.pdf
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Natural products in cancer chemotherapy: Hormones and related agents, 12th edition, 2011, 1764.
- Claudine Isaacs, Anton Wellstein, and Anna T. Riegel, Hormones and Related Agents in the Therapy of Cancer, Goodman & Gilman’s Pharmacological Basis of Therapeutics, 13th Edition, 2018, 1237-1247.
Disclaimer
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Author Details

Written By
Dr. Vijayalakshmi N.
BDS

Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 01 Apr 2026 | 12:38 PM (IST)

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