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Denaxa 60mg Injection

Prescription Required
Cold Chain Required
denosumab

8415

MRP: 17531.25

(You Save ₹9116.25)

1 PREFILLED SYRINGE(s) OF 1ML

Denaxa 60 mg Injection is a prescription medicine used to treat osteoporosis and reduce the risk of fractures in adults at high risk of bone loss. It contains denosumab, a monoclonal antibody that works by slowing bone breakdown and increasing bone strength. Denaxa is administered under medical supervision at scheduled intervals as part of a long-term bone health plan.

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Denaxa 60mg Injection
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8415

MRP: 17,531.25

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1 Prefilled Syringe(s) Of 1ml

8415.0/Unit
Prescription Required
Prescription Required
Cold Chain Required
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Salt Composition

DENOSUMAB

Marketer

ABBOTT

Prepaid Only. Non-Returnable.

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Introduction

Denaxa 60mg Injection contains the active ingredient Denosumab and is prescribed for the treatment of osteoporosis, a condition marked by weakened bones and an increased risk of fractures. It is also used to prevent bone-related complications in patients with cancers such as multiple myeloma and bone metastases. The medication works by blocking a protein called RANK ligand, which helps slow down bone tissue breakdown and promotes bone strength.

Studies have shown that Denaxa 60mg for osteoporosis helps improve bone density and lower the risk of fractures, especially in postmenopausal women and cancer patients with bone loss.

Patients can check the DENAXA 60MG INJECTION price at certified pharmacies or buy DENAXA 60MG INJECTION online from trusted sources.

The DENAXA 60MG INJECTION composition includes Denosumab 60mg as the active molecule. Doctors determine the DENAXA 60MG INJECTION dosage based on the patient’s condition. A suitable DENAXA 60MG INJECTION substitute may be recommended if needed. You can also buy Denaxa 60mg prefilled syringe conveniently online. For reference, the Denosumab 60mg vial price varies depending on manufacturer and region.

Uses

DENAXA 60MG INJECTION uses in the treatment of the following condition:

  • Osteoporosis

  • Bone loss due to hormonal therapy in breast or prostate cancer

  • Multiple myeloma (cancer affects plasma cells in the bone marrow)

  • Bone metastases (cancer that spreads to bone)

How Denaxa 60mg Injection works

Denaxa 60mg injection has therapeutic effects that include reducing fracture risk, increasing bone mineral density, and improving overall bone health. By inhibiting bone resorption through its action on RANK ligands, this medication helps to strengthen bones and decrease the likelihood of fractures in individuals with osteoporosis or those at high risk. It also increases bone mineral density, an important marker of bone strength. These therapeutic effects contribute to improved bone health and a reduced risk of fractures, ultimately enhancing the quality of life for patients.

Interaction of Denaxa 60mg Injection with other drugs

Inform the doctor about all the medicines, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Denaxa 60mg injection and reduce effectiveness by causing undesirable side effects.

Storage conditions

  • Denaxa 60mg injection should be stored in the refrigerator at a temperature between 2°C to 8°C (36°F to 46°F).

  • Do not freeze it.

  • Keep in the original package.

  • Keep away from light, moisture, and heat.

  • Keep away from children and pets.

  • Avoid taking double doses for missed doses.

How to use Denaxa 60mg Injection

Denaxa 60mg injection is given as an injection by healthcare professionals. The dosage and duration of treatment will be based on the individual's condition and response to the medication and should be determined by a healthcare provider.

Safety Advice for Denaxa 60mg Injection

Breast Feeding-Consult your doctor

Breast Feeding

Consult Your Doctor

Whether Denaxa 60mg injection is excreted in milk is unknown. So it is better to consult a healthcare provider if you are a breastfeeding mother before taking this medication.

Alcohol-unsafe

Alcohol

Unsafe

It is generally recommended to avoid or limit alcohol consumption while taking Denaxa 60mg injection. Alcohol can interact with this medication, potentially increasing the risk of side effects.

Liver-Consult your doctor

Liver

Consult Your Doctor

Denaxa 60mg injection is primarily metabolized in the liver, and its safety has not been extensively studied in individuals with severe liver impairment. It is crucial to communicate any pre-existing liver conditions or changes in liver function to your healthcare provider to ensure this medication's safe and effective use.

Lungs-Consult your doctor

Lungs

Consult Your Doctor

If you have a lung or respiratory disorders history, it is important to consult your healthcare provider before taking Denaxa 60mg injection.

Driving-unsafe

Driving

Unsafe

Patients receiving Denaxa 60mg injection should be advised to avoid driving or operating machinery if they experience side effects such as fatigue, dizziness, or blurred vision, impairing a patient's ability to drive or operate machinery safely. 

Pregnancy-Consult your doctor

Pregnancy

Consult Your Doctor

The safety of using Denaxa 60mg injection during pregnancy has not been established. Limited studies are available regarding the use of this medication in pregnant women, so it is recommended to use caution and consult a doctor before considering its use during pregnancy.

Side Effects

Denaxa 60mg injection can cause side effects like all medications, although not everyone who takes it will experience them. DENAXA 60MG INJECTION side effects are

Serious:

  • Osteonecrosis of the jaw (severe necrosis or death of jaw cells)

  • Atypical femoral fractures

  • Hypocalcemia (low blood calcium levels)

Common: 

  • Injection site reactions

  • Back pain

  • Musculoskeletal pain

  • Infections

  • Abdominal pain

  • Headache

  • Hypophosphatemia (low blood phosphate levels)

Expert tips

  • Attend all schedule appointments and follow-up visits to monitor your treatment progress and manage any side effects.

  • Inform your doctor about your complete medical history, including any previous infections, liver disease, or kidney disorders.

  • Notify your healthcare provider about any known allergies or past hypersensitivity reactions before starting the treatment.

  • Seek immediate medical attention if you experience any severe allergic reactions or serious side effects.

  • Denaxa 60mg Injection may influence calcium levels; regular monitoring and maintaining sufficient calcium and vitamin D intake are essential.

  • Pregnant and breastfeeding women should consult their doctor before taking this medication.

  • Avoid receiving vaccines during the course of treatment unless approved by your healthcare provider.

  • Maintain good oral hygiene and schedule regular dental check-ups to reduce the risk of jaw osteonecrosis.

FAQs about Denaxa 60mg Injection

Q1.

Can Denaxa 60mg injection be used in patients with a history of cancer?

Denaxa 60mg injection is not recommended in patients with a history of certain cancers, such as multiple myeloma or bone metastases. It is important to discuss your medical history and any previous or current cancer diagnoses with your healthcare provider before starting this medication.

Q2.

Can Denaxa 60mg injection be used in patients with kidney problems?

Denaxa 60mg injection is primarily eliminated through the kidneys, so caution is advised in patients with severe renal impairment or end-stage renal disease. Your healthcare provider will assess the potential risks and benefits based on your renal function.

Q3.

Can Denaxa 60mg injection be used as a treatment for osteoporosis in men?

Yes, Denaxa 60mg injection is approved for the treatment of osteoporosis in men at increased risk of fractures. It can help improve bone density and reduce fracture risk in male patients with osteoporosis.

Q4.

Can Denaxa 60mg injection be used in children and adolescents with osteoporosis?

Denaxa 60mg injection is not approved for use in children and adolescents with osteoporosis. The safety and efficacy of this medication have not been established in this population.

Q5.

Can Denaxa 60mg injection be used in individuals with dental implants?

Denaxa 60mg injection use has been associated with a slightly increased risk of jaw osteonecrosis (ONJ). Suppose you have dental implants or are considering getting them. In that case, it is important to discuss this with your dentist and healthcare provider to assess Denaxa 60mg injection's potential risks and benefits.

Q6.

What Are the Side Effects of Denaxa 60mg injection?

Denaxa 60mg injection can cause side effects like injection site reactions, back and musculoskeletal pain, infections, abdominal pain, headache, and low blood phosphate levels. Rare but serious side effects may include osteonecrosis of the jaw, atypical femoral fractures, hypocalcemia, and severe skin reactions.

Fact Box of Denaxa 60mg Injection

Molecule name

 

Denosumab

Therapeutic class

Anti-resorptive agent

Pharmacological class

Monoclonal Antibodies

Indications

1. Osteoporosis

2. Bone loss due to hormonal therapy in breast or prostate cancer

3. Multiple myeloma 

4. Bone metastases 

References

  1. Amgen Ltd, Electronic medicines compendium (EMC), [ Revised on 13th May 2023], [ Accessed on 31st May 2023],https://www.medicines.org.uk/emc/files/pil.568.pdf
  2. Amgen Manufacturing Limited, US Food and Drug Administration, [ Revised on November 2010] [ Accessed on 31st May 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/125320s007lbl.pdf 
  3. Amgen Manufacturing Limited, US Food and Drug Administration, [ Revised on November 2022] [ Accessed on 31st May 2023], https://www.fda.gov/media/163378/download

Disclaimer

MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.

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