DENAXA 60MG INJECTION uses in the treatment of the following condition:

• Osteoporosis

• Bone loss due to hormonal therapy in breast or prostate cancer

• Multiple myeloma (cancer affects plasma cells in the bone marrow)

• Bone metastases (cancer that spreads to bone)

Denaxa 60mg injection has therapeutic effects that include reducing fracture risk, increasing bone mineral density, and improving overall bone health. By inhibiting bone resorption through its action on RANK ligands, this medication helps to strengthen bones and decrease the likelihood of fractures in individuals with osteoporosis or those at high risk. It also increases bone mineral density, an important marker of bone strength. These therapeutic effects contribute to improved bone health and a reduced risk of fractures, ultimately enhancing the quality of life for patients.

Inform the doctor about all the medicines, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Denaxa 60mg injection and reduce effectiveness by causing undesirable side effects.

• Denaxa 60mg injection should be stored in the refrigerator at a temperature between 2°C to 8°C (36°F to 46°F).

• Do not freeze it.

• Keep in the original package.

• Keep away from light, moisture, and heat.

• Keep away from children and pets.

• Avoid taking double doses for missed doses.

Denaxa 60mg injection is given as an injection by healthcare professionals. The dosage and duration of treatment will be based on the individual's condition and response to the medication and should be determined by a healthcare provider.

Denaxa 60mg injection can cause side effects like all medications, although not everyone who takes it will experience them. DENAXA 60MG INJECTION side effects are

Serious:

• Osteonecrosis of the jaw (severe necrosis or death of jaw cells)

• Atypical femoral fractures

• Hypocalcemia (low blood calcium levels)

Common: 

• Injection site reactions

• Back pain

• Musculoskeletal pain

• Infections

• Abdominal pain

• Headache

• Hypophosphatemia (low blood phosphate levels)

• Attend all schedule appointments and follow-up visits to monitor your treatment progress and manage any side effects.

• Inform your doctor about your complete medical history, including any previous infections, liver disease, or kidney disorders.

• Notify your healthcare provider about any known allergies or past hypersensitivity reactions before starting the treatment.

• Seek immediate medical attention if you experience any severe allergic reactions or serious side effects.

• Denaxa 60mg Injection may influence calcium levels; regular monitoring and maintaining sufficient calcium and vitamin D intake are essential.

• Pregnant and breastfeeding women should consult their doctor before taking this medication.

• Avoid receiving vaccines during the course of treatment unless approved by your healthcare provider.

• Maintain good oral hygiene and schedule regular dental check-ups to reduce the risk of jaw osteonecrosis.

1. Amgen Ltd, Electronic medicines compendium (EMC), [ Revised on 13th May 2023], [ Accessed on 31st May 2023],https://www.medicines.org.uk/emc/files/pil.568.pdf
2. Amgen Manufacturing Limited, US Food and Drug Administration, [ Revised on November 2010] [ Accessed on 31st May 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/125320s007lbl.pdf 
3. Amgen Manufacturing Limited, US Food and Drug Administration, [ Revised on November 2022] [ Accessed on 31st May 2023], https://www.fda.gov/media/163378/download