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Denmab 60mg Injection

Prescription Required
Cold Chain Required
denosumab

₹5492

MRP: ₹6697.5

(You Save ₹1205.5)

1 PREFILLED SYRINGE(s) OF 1ML

New Price · NPPA Revised MRP
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Denmab 60mg Injection
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₹5492

MRP: ₹6,697.50

Inclusive of all taxes

18% Off

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1 Prefilled Syringe(s) Of 1ml

1 Prefilled Syringe(s) Of 1ml

₹ 5492.0/Unit
Prescription Required
Prescription Required
Cold Chain Required
Cold Chain
Info

Salt Composition

DENOSUMAB

Marketer

EMCURE PHARMACEUTICALS LTD

Prepaid Only. Non-Returnable.

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Introduction

Denmab 60mg Injection consists of the active ingredient Denosumab. This denmab injection is used to treat osteoporosis, a condition characterized by weakened bones. It is also prescribed to prevent bone complications in patients with certain types of cancer, such as multiple myeloma and bone metastases.

Denmab 60mg Injection works by inhibiting a protein called RANK ligand, which plays a role in the breakdown of bone tissue. Studies have shown that denmab can significantly increase bone density and reduce fracture risk in postmenopausal women with osteoporosis and patients with cancer-related bone loss.

Doctors may advise caution and close monitoring of renal function in patients with moderate kidney impairment. Patients searching for cost details can check the denmab 60 mg injection price before starting treatment. Always use this medicine under medical supervision.

Uses

denub 60 mg injection uses are:

  • Osteoporosis
  • Bone loss due to hormonal therapy in breast or prostate cancer
  • Multiple myeloma (cancer affects plasma cells in the bone marrow)
  • Bone metastases (cancer that spreads to bone).

How Denmab 60mg Injection works

Denmab 60mg Injection has therapeutic effects that include reducing fracture risk, increasing bone mineral density, and improving overall bone health. By inhibiting bone resorption through its action on RANK ligands, this medication helps to strengthen bones and decrease the likelihood of fractures in individuals with osteoporosis or those at high risk. It also increases bone mineral density, an important marker of bone strength. These therapeutic effects contribute to improved bone health and a reduced risk of fractures, ultimately enhancing the quality of life for patients.

Interaction of Denmab 60mg Injection with other drugs

Inform the doctor about all the medicines, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Denmab 60mg Injection and reduce effectiveness by causing undesirable side effects.

Storage conditions

  • Denmab 60mg Injection should be stored in the refrigerator at a temperature between 2°C to 8°C (36°F to 46°F).
  • Do not freeze it.
  • Keep in the original package.
  • Keep away from light, moisture, and heat.
  • Keep away from children and pets.
  • Avoid taking double doses for missed doses.

How to use Denmab 60mg Injection

Denmab 60mg Injection is given as an injection by healthcare professionals. The dosage and duration of treatment will be based on the individual's condition and response to the medication and should be determined by a healthcare provider.

Safety Advice for Denmab 60mg Injection

Breast Feeding-Consult your doctor

Breast Feeding

Consult Your Doctor

Whether Denmab 60mg Injection is excreted in milk is unknown. So it is better to consult a healthcare provider if you are a breastfeeding mother before taking this medication.

Alcohol-unsafe

Alcohol

Unsafe

It is generally recommended to avoid or limit alcohol consumption while taking Denmab 60mg Injection. Alcohol can interact with this medication, potentially increasing the risk of side effects.

Liver-Consult your doctor

Liver

Consult Your Doctor

Denmab 60mg Injection is primarily metabolized in the liver, and its safety has not been extensively studied in individuals with severe liver impairment. It is crucial to communicate any pre-existing liver conditions or changes in liver function to your healthcare provider to ensure this medication's safe and effective use.

Lungs-Consult your doctor

Lungs

Consult Your Doctor

If you have a lung or respiratory disorders history, it is important to consult your healthcare provider before taking Denmab 60mg Injection.

Driving-unsafe

Driving

Unsafe

Patients receiving Denmab 60mg Injection should be advised to avoid driving or operating machinery if they experience side effects such as fatigue, dizziness, or blurred vision, impairing a patient's ability to drive or operate machinery safely. 

Pregnancy-Consult your doctor

Pregnancy

Consult Your Doctor

The safety of using Denmab 60mg Injection during pregnancy has not been established. Limited studies are available regarding the use of this medication in pregnant women, so it is recommended to use caution and consult a doctor before considering its use during pregnancy.

Side Effects

Denmab 60mg Injection can cause side effects like all medications, although not everyone who takes it will experience them.Denmab 60 injection side effects are

Serious:

  • Osteonecrosis of the jaw (severe necrosis or death of jaw cells)
  • Atypical femoral fractures
  • Hypocalcemia (low blood calcium levels)

Common: 

  • Injection site reactions
  • Back pain
  • Musculoskeletal pain
  • Infections
  • Abdominal pain
  • Headache
  • Hypophosphatemia (low blood phosphate levels)

Expert Tips

  • Attend all scheduled appointments and follow-up visits to monitor your response to treatment and address any concerns or side effects.

  • Inform your doctor about your medical history, including previous infections, liver disease, and kidney disease.

  • Tell your healthcare provider about any allergies or hypersensitivity reactions you may have.

  • Seek immediate medical attention if you experience severe allergic reactions or other serious side effects.

  • Denmab 60mg Injection may affect calcium levels, so it is important to monitor calcium levels and ensure adequate calcium and vitamin D intake.

  • Pregnant and breastfeeding women should consult a doctor before taking this medication.

  • Avoid taking any vaccines during treatment.

  • Regular dental check-ups and good oral hygiene practices are recommended to minimize the risk of jaw osteonecrosis.

FAQs about Denmab 60mg Injection

Q1.

Can Denmab 60mg Injection be used in patients with a history of cancer?

Denmab 60mg Injection is not recommended in patients with a history of certain cancers, such as multiple myeloma or bone metastases. It is important to discuss your medical history and any previous or current cancer diagnoses with your healthcare provider before starting this medication.

Q2.

Can Denmab 60mg Injection be used in patients with kidney problems?

Denmab 60mg Injection is primarily eliminated through the kidneys, so caution is advised in patients with severe renal impairment or end-stage renal disease. Your healthcare provider will assess the potential risks and benefits based on your renal function.

Q3.

Can Denmab 60mg Injection be used as a treatment for osteoporosis in men?

Yes, Denmab 60mg Injection is approved for the treatment of osteoporosis in men at increased risk of fractures. It can help improve bone density and reduce fracture risk in male patients with osteoporosis.

Q4.

Can Denmab 60mg Injection be used in children and adolescents with osteoporosis?

Denmab 60mg Injection is not approved for use in children and adolescents with osteoporosis. The safety and efficacy of this medication have not been established in this population.

Q5.

Can Denmab 60mg Injection be used in individuals with dental implants?

Denmab 60mg Injection use has been associated with a slightly increased risk of jaw osteonecrosis (ONJ). Suppose you have dental implants or are considering getting them. In that case, it is important to discuss this with your dentist and healthcare provider to assess Denmab 60mg Injection's potential risks and benefits.

Q6.

What Are the Side Effects of Denmab 60mg Injection?

Denmab 60mg Injection can cause side effects like injection site reactions, back and musculoskeletal pain, infections, abdominal pain, headache, and low blood phosphate levels. Rare but serious side effects may include osteonecrosis of the jaw, atypical femoral fractures, hypocalcemia, and severe skin reactions.

Fact Box of Denmab 60mg Injection

Molecule name

 

  Denosumab

Therapeutic class

Anti-resorptive agent

Pharmacological class

Monoclonal Antibodies

Indications

1. Osteoporosis

2. Bone loss due to hormonal therapy in breast or prostate cancer

3. Multiple myeloma 

4. Bone metastases 

 

References

  1. Amgen Ltd, Electronic medicines compendium (EMC), [ Revised on 13th May 2023], [ Accessed on 31st May 2023],https://www.medicines.org.uk/emc/files/pil.568.pdf
  2. Amgen Manufacturing Limited, US Food and Drug Administration, [ Revised on November 2010] [ Accessed on 31st May 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/125320s007lbl.pdf 
  3. Amgen Manufacturing Limited, US Food and Drug Administration, [ Revised on November 2022] [ Accessed on 31st May 2023], https://www.fda.gov/media/163378/download

Disclaimer

MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.

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Author Details
Dr. Archana Gupta

Written By

Dr. Archana Gupta

BDS

Dr. Tejashwin Adiga

Reviewed By

Dr. Tejashwin Adiga

MBBS

Last updated : 09 Nov 2026 | 04:44 AM (IST)

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