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Salt Composition : Aprepitant
Manufacturer : MSD PHARMACEUTICALS PVT LTD
Origin of Medicine : United States of America
3 Capsule(s) In A Strip
Introduction to Emend Capsule
Emend 125mg/80mg capsule contains the active constituent Aprepitant in two different doses. It belongs to a class of medicines called NK1 Receptor antagonists. It is used with a combination of other medicine to prevent nausea and vomiting caused by chemotherapy (cancer treatment) in adults and children of twelve years and older. Do not take this medicine if you are allergic to this medicine or any of the other ingredients of this medicine.
Before taking Emend 125mg/80mg capsule, it is important to inform your physician about all the medications you are taking recently, including supplements and herbal medicines. Notify your doctor if you planning a pregnancy or think you might be pregnant because this medicine is unsafe to use in such conditions. This medication may reduce the efficacy of hormonal contraceptives. Talk with your doctor about alternative birth control options. Before taking this capsule, inform your doctor if you have liver disorders because the liver is crucial in breaking down medicine.
The doctor may therefore have to monitor the condition of the liver. Notify your doctor if you have had any allergic conditions or other diseases. Indigestion, tiredness, headache, hiccups, and loss of appetite are the common side effects of Emend 125mg/80mg medication. Talk to your doctor if you have an intolerance to some sugars as this medication contains sucrose. Do not give this medicine to children under 12 years of age, because the medicines have not been studied in this population.
Uses of Emend Capsule
- Prevents nausea and vomiting due to chemotherapy
Therapeutic Effects of Emend Capsule
Emend 125mg/80mg capsule blocks the action of a natural substance called neurokinin in the brain that causes nausea and vomiting. This medicine reduces the severity of chemotherapy-induced nausea and vomiting.
Interaction of Emend Capsule with other drugs
Inform your healthcare provider about all your medicines, including prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products. Certain medications, such as Pimpzide, Terfenadine, and Cisapride may interact with Emend 125mg/80mg and reduce effectiveness by causing undesirable side effects.
More Information about Emend Capsule
- Store at room temperature 20°C to 25°C.
- Keep out of sight and reach of children.
- Store in the original package in order to protect it from moisture.
How to consume Emend Capsule
Swallow the Emend 125mg/80mg capsule as a whole with water. Do not crush or chew the capsules. These capsules can be taken with or without food. Do not take more than recommended. If this medicine is prescribed, your physician will choose the dosage based on your medical condition because it differs for each person.
Safety Advices for Emend Capsule
This medication is unsafe because it may harm your unborn baby. Inform your physician if you are pregnant or planning to get pregnant before taking the Emend 125mg/80mg capsule. It will be given to you if clearly needed.
It is unknown whether Emend 125mg/80mg is excreted in human milk. So, it is not recommended to breastfeed while taking this capsule. Inform your physician before taking this medicine.
Inform your doctor, if you have or had any lung condition before starting to take Emend 125mg/80mg. Contact your physician immediately if you experience any lung-related symptoms such as difficulty to breath.
Inform your physician if you have any liver disorders before taking the Emend 125mg/80mg capsule, as this medication should be used with caution in liver disorder patients.
It is unknown whether consuming alcohol with Emend 125mg/80mg. Consult your doctor for more information.
The medicine may make you dizzy. Avoid driving or handling heavy machines if you are unwell.
Side Effects of Emend Capsule
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
- Allergic reactions (rash, itching, difficulty breathing, or swallowing)
- Increased liver enzyme
- Loss of appetite
Word of Advice
Report to your doctor if you are intolerant to any type of sugar because Emend 125mg/80mg contains sucrose. It is not advised for patient under the age of 12. Notify your doctor if you are pregnant or planning to get pregnant or if you are breastfeeding. It is not recommended to consume this medicine if you have any underlying liver conditions. Your doctor may monitor your liver to understand its functioning level.
Q 1. Can Emend 125mg/80mg be taken with other medications?
Emend 125mg/80mg can be taken with other antiemetic drugs to provide more comprehensive prevention of chemotherapy-induced nausea and vomiting.
Q 2. Can Emend 125mg/80mg be used to treat other conditions?
Emend 125mg/80mg is primarily used to prevent nausea and vomiting caused by chemotherapy or surgery, but it may also be used to treat other conditions, such as migraine headaches.
Q 3. Why patients with liver conditions should not consume Emend 125mg/80mg?
Because the Emend 125mg/80mg initially gets metabolized in the liver. Hence patients with liver disorders will feel difficult to metabolize this medicine which may lead to an increasing risk of side effects.
Q 4. What should I inform my doctor before starting with Emend 125mg/80mg?
You need to inform, if you have any underlying liver conditions if you are allergic to Emend 125mg/80mg, and if you are intolerant to sucrose or any other sugar.
Q 5. Is Emend 125mg/80mg safe for use during pregnancy?
Emend 125mg/80mg should only be used during pregnancy if the potential benefits outweigh the potential risks to the fetus.
Fact Box of Emend Capsule
Molecule name: Aprepitant
Therapeutic class: Antiemetic
Pharmacological class: NK1 Receptor antagonists
Indication: Prevents nausea and vomiting due to chemotherapy
- KD Tripathi, Essentials of Medical Pharmacology, Antiemetic, Prokinetic and Digestant Drugs, 7th edition, 2013, 669-670.
- Goodman & Gilman’s, The Pharmacological Basics of Therapeutics, Treatment of disorders of bowel motility and water flux, 12th edition, 2011, 1345.
- Ethypharm, Electronic Medicines Compendium (EMC), [Revised on Oct 2022]; [Accessed on 19th April 2023], https://www.medicines.org.uk/emc/files/pil.14650.pdf
- Merck Sharp & Dohme Corp, US Food and Drug Administration, [Revised date April 2015], [Accessed on 19th April 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/021549s025lbl.pdf
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