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Endoxan N 1gm Injection
Salt Composition : Cyclophosphamide
Manufacturer : ZYDUS CADILA
Origin of Medicine : India
Introduction to Endoxan N 1gm Injection
Endoxan N 1gm Injection is a chemotherapy drug containing the active constituent cyclophosphamide. It is used to treat various malignancies (abnormal production of cells is called cancer, and if they spread to other organs, they are called malignancies). Endoxan N 1gm Injection can be used to treat malignant lymphomas (cancers that start from the lymphatic system of the body- vessels, fluid, and lymphoid tissue) such as Hodgkin’s disease, lymphocytic lymphoma, and mixed-cell type lymphoma.
It is used to treat leukemias, neuroblastoma, ovarian cancer, retinoblastoma, and breast carcinoma. It can also treat Minimal Change Nephrotic syndrome in pediatric patients (kidney disease in which large quantities of protein are lost in urine). Endoxan N 1gm Injection is contraindicated in pregnancy, patients with acute infections, urinary tract infections, urinary outflow obstruction, and bone marrow disorders.
Treatment with this medicine may lead to immune suppression, bone marrow failure, cardiotoxicity, renal toxicity, pulmonary toxicity, and secondary malignancies. Inform your doctor if you have pre-existing kidney disease, immune conditions, cardiac disorders, or liver diseases.
Uses of Endoxan N 1gm Injection
- Malignant lymphomas
- Carcinoma of breast
- Ovarian cancer
- Mycosis fungoides
- Minimal Change Nephrotic Syndrome in Pediatric Patients
Therapeutic Effects of Endoxan N 1gm Injection
Endoxan N 1gm Injection Injection slows or stops the growth of cancer cells by damaging the hereditary material (DNA and RNA) of the cancer cells. In nephrotic syndrome, it works by suppressing the body’s immune system.
Interaction of Endoxan N 1gm Injection with other drugs
Inform your doctor about any prescribed medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products that you are taking or have taken before the treatment. Certain medications may interact with Endoxan N 1gm Injection and cause potential side effects.
More Information about Endoxan N 1gm Injection
Keep out of sight and reach of children. Store vials below or at 25°C.
How to consume Endoxan N 1gm Injection
Endoxan N 1gm Injection will be administered intravenously by healthcare professionals experienced in cancer chemotherapy. Do not self-administer.
Safety Advices for Endoxan N 1gm Injection
Endoxan N 1gm Injection can cause fetal harm when administered to a pregnant woman. Inform your physician if you are pregnant or planning to get pregnant before taking this medication. Your physician will instruct you to take it when it is necessary.
Avoid Endoxan N 1gm Injection if you are breastfeeding. Consult your doctor for potential risks and benefits.
It is unknown whether Endoxan N 1gm Injection can be given in lung failure patients. Inform your doctor if you have any lung diseases.
Endoxan N 1gm Injection should be used with caution in patients with liver disease. Please consult your doctor.
It is unsafe to consume alcohol with Endoxan N 1gm Injection. Please consult your doctor for more advice.
It is not recommended while driving because it causes dizziness, and patients may lack concentration and alertness.
Side Effects of Endoxan N 1gm Injection
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
- Immune suppression
- Blood disorders
- Allergic reactions
- Abnormal liver function
- Inflammation of the bladder
- Kidney diseases
- blood in urine
- impaired wound healing
- Nausea, vomiting
- Low white blood cell count
- Hair loss
- Blurred vision
Word of Advice
Inform the doctor if the patient has any kidney, liver, or heart problems and medication taken for different medical conditions. It causes immune suppression and hence inform the doctor if there are any immune problems. Avoid this medication if the patient is pregnant or breastfeeding mother. The patient undergoing treatment with Endoxan N 1gm Injection may have dizziness, and blurred vision. Consult your doctor before driving and handling heavy machines.
Q 1. Can Endoxan N 1gm Injection cause infertility?
Yes, Endoxan N 1gm Injection can cause infertility in both men and women hence consult the doctor before taking this medication.
Q 2. Is Endoxan N 1gm Injection chemotherapy medication?
Yes, Endoxan N 1gm Injection is a chemotherapy medicine, and it works by killing cancer cells. It prevents the spreading of cancer cells to different parts.
Q 3. Can Endoxan N 1gm Injection cause weight loss?
Yes, Endoxan N 1gm Injection causes weight loss due to reduced appetite, and consult the doctor if there is excessive weight loss.
Q 4. Can Endoxan N 1gm Injection be used during pregnancy?
No, it is highly unsafe to use this medication during pregnancy as it can cause harmful effects on the developing baby.
Q 5. Can Endoxan N 1gm Injection cause hair loss?
Yes, Endoxan N 1gm Injection can cause hair loss, and consult the doctor if there is excessive hair loss.
Q 6. Can I take Endoxan N 1gm Injection while driving?
No, it is not recommended while driving because it makes patients dizzy, and patients may lack concentration and alertness.
Fact Box of Endoxan N 1gm Injection
|Molecule Name: Cyclophosphamide
|Pharmacological Class: Alkylating agent
1. Malignant lymphomas
2. Treat certain types of cancers such as eye, blood, breast, and ovarian cancer.
3. Minimal Change Nephrotic Syndrome in Pediatric Patients
- KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 860.
- Baxter, Electronic medicines compendium (emc), [ Revised on June 2016] [ Accessed on 8th April 2021], https://www.medicines.org.uk/emc/product/1815/smp
- Baxter, US Food and Drug Administration, [ Revised on May 2013] [ Accessed on 7th April 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/012141s090,012142s112lbl.pdf
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