• Treatment of cardiac arrest

• Management of low blood pressure associated with septic shock

• Severe allergic reactions

• Pupil enlargement and maintenance during eye surgery

Epineph 1mg injection works on two types of receptors in your body, called alpha (α) and beta (β) receptors, in various organs:

• Heart: It makes your heart pump stronger and faster, which can be helpful during a heart emergency like cardiac arrest.
• Blood vessels: It tightens your blood vessels, which can be used when treating low blood pressure in cases like septic shock.
• Lungs: It relaxes the muscles in your lungs, making breathing easier if you have a severe allergic reaction (anaphylaxis).
• Eyes: It makes your pupil (the black part in your eye) get bigger, which helps doctors during eye surgery to operate better.

Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Epineph 1mg injection  and cause undesirable side effects. 

• Store below 25°C.
• Protect from light.
• Keep out of reach of children.
• Do not use it after the expiry date.

This medicine is given only in a hospital set up by a trained healthcare provider during an emergency. Epineph 1mg injection may be injected either into your muscle or into the tissue just beneath your skin. Your doctor will decide the most apt dosage for you based on your age and physical circumstances.  

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.

Serious

• Stress cardiomyopathy - Symptoms of chest pain, shortness of breath, nausea, or an irregular heartbeat, especially if you are stressed.

Common

• Anxiety and  restlessness
• Tremor (involuntary shaking)
• Weakness and dizziness,
• Sweating, palpitations or pallor
• Nausea and vomiting
• Headache
• Respiratory difficulties

Since epineph 1mg injection is an emergency drug, you will be under medical supervision during and, if necessary, after the treatment. If you experience any side effects during or after treatment, inform your healthcare provider promptly. Avoid spicy and fatty foods. Take plant-based diets. Avoid alcohol and quit smoking to resume a healthy lifestyle.

1. Mercury Pharmaceuticals Ltd, Electronic medicines compendium (EMC), [Revised on Nov 2018], [Accessed on 26th Sep 2023], https://www.medicines.org.uk/emc/product/6595/pil

2. Belcher Pharmaceuticals, US Food and Drug Administration (FDA), [Revised on July 2021], [Accessed on 26th Sep 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/205029s006lbl.pdf

3. KD Tripathi, Essentials of Medical Pharmacology, Adrenergic Transmission and Adrenergic Drugs, 8th edition, 2019, 145-152

4. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Adrenergic agonists and Antagonists,13th edition, 2018, 194-196