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Estogel Gel 80gm
Last updated on 13 May 2026 | 07:12 AM (IST)
₹971
MRP: ₹1334.53
(You Save ₹363.53)
1 TUBE OF 80GM
Estogel Gel 80gm is a prescription medicine used for hormone replacement therapy in women with low oestrogen levels, especially during menopause. It contains oestradiol, a form of the natural female hormone oestrogen, which helps relieve symptoms such as hot flushes, night sweats, mood changes, and vaginal dryness. The gel is applied to the skin, allowing the hormone to be absorbed gradually into the bloodstream. Estogel Gel 80gm should be used under strict medical supervision as part of a comprehensive hormone replacement plan.
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Introduction
Estogel Gel 80gm manufactured by Intas contains estradiol as the active ingredient, belonging to vaginal Hormone Replacement Therapy (HRT). Estogel Gel for HRT falls within the estrogen hormone category and shares identical properties with naturally occurring estrogen synthesized by women's ovaries. Estogel Gel uses for menopause include treating menopausal symptoms such as vaginal atrophy. Estogel Gel 80gm for vaginal dryness and Estogel Gel for hot flashes effectively addresses dryness or irritation of the vagina in elderly women who have passed menopause. Follow proper instructions on how to apply Estogel Gel as directed by your healthcare provider regarding Estogel Gel dosage.
It is not recommended to use this medication if you are allergic to estradiol and its constituents. Avoid use if you have breast cancer, estrogen receptor-sensitive cancers, clotting disorders, blood clots in veins (lungs or legs), or unexplained vaginal bleeding. It is not advised if you have heart attack, stroke, angina, abnormal liver function tests, or porphyria. The risk of gallbladder disease is elevated by estrogen intake. Stop using if you experience cholestatic jaundice, severe hypertriglyceridemia, severe hypercalcemia, or vision loss. Monitor women receiving thyroid replacement treatment.
Inform your doctor if you have vaginal bleeding, heart, kidney, lung or liver problems, diabetes, asthma, high blood pressure, or hearing disorders. Consult your doctor if planning pregnancy or breastfeeding. Estogel Gel 80gm price varies by location. Buy Estogel Gel 80gm online from authorized retailers. Estogel Gel substitute options are available; consult your doctor before switching. Estogel Gel review from users highlights effectiveness. Inform your healthcare provider about all medicines including herbal, vitamin, and over-the-counter medications.
Uses
Relieve menopausal symptoms of 'vaginal atrophy' (in the vagina such as dryness or irritation)
Treatment for hypogonadism, castration, or primary ovarian failure-related hypoestrogenism
Preventing osteoporosis after menopause
How Estogel Gel 80gm works
Estogel Gel 80gm primarily acts by binding to estrogen receptors (ERs) present on the surface of target cells upon binding to its receptor, Estogel Gel 80gm induces a conformational change in the receptor, leading to its activation. Estogel Gel 80gm replaces estrogen (female sex hormone) and prevents the symptoms of menopause, like vaginal irritation or dryness.
Interaction of Estogel Gel 80gm with other drugs
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Estogel Gel 80gm and can cause undesirable side effects.
Storage conditions
Protect from moisture
Store Estogel 80gm Gel at 25˚C
Keep children away from the sight and reach of this medication.
How to use Estogel Gel 80gm
Take Estogel Gel 80gm exactly as prescribed by your healthcare provider. Do not adjust the dosage or frequency without consulting your doctor. Take your Estogel Gel 80gm at the same time each day to maintain a consistent level of hormones in your body. Swallow the Estogel Gel 80gm whole with a glass of water. Do not crush, chew, or break the tablet, as this may affect its effectiveness or increase the risk of side effects.
Safety Advice for Estogel 80gm Gel
Breast Feeding
It is unknown whether Estogel Gel 80gm is excreted in breast milk. Consult your doctor before using it. Seek your doctor for more information.
Alcohol
It is unknown whether it is safe to consume alcohol under medication. So, it is recommended to consult your doctor before taking medicine.
Liver
Inform your physician about any underlying liver disorders before taking Estogel Gel 80gm, as this medication should be used cautiously in liver disease patients.
Lungs
Inform your physician about any underlying lung disorders before taking Estogel Gel 80gm as this medication should be used cautiously in lung disease patients.
Driving
It is unknown whether Estogel Gel 80gm alters driving ability. However, if you experience side effects like tiredness or drowsiness, avoid driving and using machines.
Pregnancy
Estogel Gel 80gm is not recommended for pregnant women. Notify your healthcare professional if you are pregnant or planning to have a baby think you may be pregnant.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Estogel Gel side effects are
Common
Headache
Stomach pain
Vaginal bleeding
Discharge or discomfort.
Serious:
Ovarian cancer
Blood clots
Heart attack
Breast lumps
Stroke
Expert tips
It is recommended to examine your breast (mammogram) to avoid the risk of breast cancer caused by the drug and inform your doctor if you have any changes in skin colour
Don't apply it on your breast, eye, or other part of the body apart from the application site
Inform your doctor if you have uterus cancer or a history of blood clots
Regularly monitoring liver function tests, thyroid tests, bone mineral density, and blood pressure is advised as treatment with Estogel Gel 80gm can alter these values.
FAQs about Estogel 80gm Gel
Q1.
What are the precautions I need to take while taking Estogel Gel 80gm?
Inform the doctor of your medical history. It will be useful for him to treat you based on your health. Inform your doctor if you have kidney, liver, or heart disease, diabetes, gallbladder problems, or asthma before starting to use the medicine.
Q2.
Can I suddenly stop taking Estogel Gel 80gm?
Stopping your Estogel Gel 80gm treatment suddenly without first talking to your doctor is not advised. When estrogen medication is abruptly stopped, withdrawal symptoms and maybe rebound effects might occur. Talk to your healthcare practitioner about stopping or altering your therapy so that a safe and gradual plan may be created.
Q3.
Can I take Estogel Gel 80gm if I have a history of allergies to it?
Consult your doctor if you are allergic to Estogel Gel 80gm or any of the ingredients should be used before starting the medicine.
Q4.
What happens if a pregnant woman takes Estogel Gel 80gm?
Estogel Gel 80gm is not recommended for premenopausal women or pregnant women, as it may cause undesirable side effects if it is used during the period of pregnancy.
Q5.
Is there any possibility of having breast cancer when I use Estogel Gel 80gm?
Yes, Estogel Gel 80gm may cause breast cancer as a side effect. So, it is advised that you examine your breasts while under medication.
Fact Box
Molecule name | Estradiol |
Therapeutic class | Hormones |
Pharmacological class | Androgens |
Indications | 1. Relieve menopausal symptoms of 'vaginal atrophy' (in the vagina such as dryness or irritation) 2. Treatment for hypogonadism, castration, or primary ovarian failure-related hypoestrogenism 3. Preventing osteoporosis after menopause |
References
- Mercury Pharmaceuticals Limited, Electronics Medicines Compendium (EMC), [Revised on Jan 2024], [Accessed on 13th March 2024] , https://www.medicines.org.uk/emc/files/pil.11779.pdf
- Ther-Rx Corporation, US Food and Drug Administration,[Revised on April 2008], [Accessed on 13th March 2024], https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/022014s001lbl.pdf
- Pfizer, [Revised on Feb 2024], [Accessed on 13th March 2024], https://labeling.pfizer.com/ShowLabeling.aspx?id=595
- Novartis Pharmaceuticals Corporation, [Revised on October 2021], [Accessed on 13th March 2024], https://www.novartis.com/us-en/sites/novartis_us/files/Vivelle_DOT.pdf
- KD Tripathi, Essentials of Medical Pharmacology, Androgens and drugs for erectile dysfunction, 7th edition, 2013, 296-300.
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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Author Details
Written By
Dr. Vijayalakshmi N.
BDS
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 13 May 2026 | 07:12 AM (IST)
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