Your doctor may prescribe Everbliss 10mg Tablet for:

• Advanced hormone receptor-positive breast cancer (usually after failure of other therapies)

• Advanced renal cell carcinoma (kidney cancer)

• Advanced pancreatic neuroendocrine tumors

• Treatment of subependymal giant cell astrocytoma in patients unsuitable for surgery

Some patients also explore Everbliss 10mg Tablet alternatives when they develop intolerance or inadequate response to Everolimus.

The Everbliss 10mg tablet acts by blocking a protein called mTOR, which plays a key role in cell growth and division. By inhibiting mTOR, this medicine helps slow down or stop the growth of cancer cells and tumor tissues. This targeted action reduces tumor size and disease progression in cancer patients.

Like many antineoplastic treatments, the tablet form ensures systemic circulation, allowing the drug to reach the site of tumors effectively.

Before starting Everbliss 10mg Tablet, inform your doctor about all medications you are currently taking, including:

• Prescription drugs for infections or epilepsy

• Antifungal medications (like ketoconazole)

• Antibiotics and antiviral drugs

• Blood pressure medications

• Herbal supplements and over-the-counter products

Avoid live vaccines during treatment, and keep your doctor informed if you’re scheduled for surgery. Grapefruit and grapefruit juice should also be avoided as they may increase Everolimus blood levels.

• Store Everbliss 10mg Tablet at room temperature (20°C to 25°C) in its original packaging

• Keep out of reach of children and pets

• Do not freeze

• If you miss a dose, skip it and continue with your next scheduled dose. Do not double-dose

Take Everbliss 10mg Tablet exactly as prescribed by your doctor. Swallow the tablet whole with a glass of water, preferably at the same time every day. It can be taken with or without food, but be consistent with your choice.

Do not break, chew, or crush the tablet. If you forget to take a dose, skip it if it’s nearly time for your next one. Avoid taking two doses together.

Like all cancer medications, Everbliss 10mg Tablet can cause side effects. These vary from person to person.

Common side effects

• Mouth ulcers or sores

• Fever, chills, or infections

• Cough and shortness of breath

• Tiredness

• Increased thirst and urination

• Bleeding issues

• Appetite changes with weight loss
  
  

Serious side effects (less common):

• Difficulty breathing or swallowing

• Swelling of face, lips, or throat

• Severe skin rash or itching

• Signs of kidney or liver injury

If you notice any severe or unusual symptoms, inform your doctor immediately.

• Maintain good oral hygiene and use any medicated mouthwash prescribed by your doctor to reduce mouth ulcers.

• Avoid sun exposure and always use sunscreen while on Everbliss 10mg Tablet to lower skin cancer risk.

• Do not take live vaccines during treatment.

• Inform your doctor if you have a history of hepatitis B, heart failure, or high cholesterol.

• Stick to your blood tests and monitoring schedule for white blood cell count, platelets, and kidney function.

• Discuss effective contraception methods with your doctor, and continue using them during treatment and for at least 8 weeks after the last dose.

1. Accord Healthcare Limited, Electronic medicines compendium (EMC), [ Revised on Oct 2020] [ Accessed on 18th March 2023], https://www.medicines.org.uk/emc/files/pil.11084.pdf
2. Jan Hasskarl; Everolimus; Recent Results in Cancer Research; Published on 2018; Accessed on 18/03/2023; https://pubmed.ncbi.nlm.nih.gov/30069763/
3. Novartis Pharmaceuticals Corporation, US Food and Drug Administration, [ Revised on July 2012] [ Accessed on 18th March 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/022334s016lbl.pdf
4. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Targeted therapy: tyrosine kinase inhibitors, monoclonal antibodies and cytokines, 12th edition, 2011, 1743.
5. KD Tripathi, Essentials of Medical Pharmacology, Immunosuppressant drugs, 7th edition, 2013, 878 - 882.