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Exena S 25mg/5mg Tablet
Prescription Required
Salt Composition : Mirabegron,solifenacin
Manufacturer : DR REDDY'S LABORATORIES LTD
Origin of Medicine : India
10 Tablet(s) In A Strip
Introduction to Exena S 25mg/5mg Tablet
Exena S 25mg/5mg Tablet contains two active ingredients called Mirabegron and Solifenacin. It belongs to the family of Beta 3-adrenoceptor agonists and muscarinic receptor antagonists. This medicine reduces the activity and symptoms associated with an overactive bladder, such as urgency incontinence (inability to control bladder emptying), sudden urination urges, and increased urinary frequency. This medicine is not advised for use in children under 18 years old.
Exena S 25mg/5mg Tablet should not be taken if you have allergies to Mirabegron or Solifenacin or if you have high uncontrolled blood pressure. Before starting the treatment, inform your doctor if you have trouble emptying your bladder (urinary retention) or if you are taking specific medications for HIV, fungal or bacterial infections, or anticholinergic medicine. Avoid taking this medicine if you have a severe stomach or bowel condition such as a toxic megacolon, muscle disease (myasthenia gravis), or glaucoma with progressive vision loss. It is recommended not to consume this medicine if you are undergoing kidney dialysis or if you have severe liver disease.
Don't consume Exena S 25mg/5mg Tablet if you are pregnant or planning to get pregnant or breastfeeding. Before starting the treatment, notify your doctor if you have liver or kidney problems. Your doctor may adjust your dose in such conditions. Also, inform your doctor if you have any heart conditions, such as abnormal ECG (QT prolongation) or taking medications that may cause it. Report to your doctor if you have constipation, stomach tear (hiatus hernia), heartburn, or nervous disorder (autonomic neuropathy).
Uses of Exena S 25mg/5mg Tablet
- Treatment of overactive bladder (OAB) symptoms.
- It helps to control uncontrollable bladder emptying (urgency incontinence).
- Reduce sudden urges to urinate.
- Reduce frequent urination.
Therapeutic Effects of Exena S 25mg/5mg Tablet
Exena S 25mg/5mg Tablet work together to improve bladder function. Mirabegron stimulates beta-3 adrenergic receptors, leading to the relaxation of bladder muscles, increased bladder capacity, and reduced urgency and frequency of urination. Solifenacin, on the other hand, blocks muscarinic receptors, relaxing the bladder muscles, reducing contractions, and increasing bladder capacity. This combined action helps improve overall bladder control and reduce urinary symptoms.
Interaction of Exena S 25mg/5mg Tablet with other drugs
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications, such as itraconazole, ketoconazole, and clarithromycin, may interact with Exena S 25mg/5mg Tablet and can cause undesirable side effects.
More Information about Exena S 25mg/5mg Tablet
- Keep out of sight and reach of pets and children.
- Do not freeze the medicine.
- Do not store above 30°C.
- Always check the expiry date before consuming it.
How to consume Exena S 25mg/5mg Tablet
Take the Exena S 25mg/5mg Tablet as your physician advises. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.
Safety Advices for Exena S 25mg/5mg Tablet
Pregnancy
Exena S 25mg/5mg Tablet is unsafe during pregnancy as it may harm the developing baby. Before starting the treatment, inform your doctor if you are pregnant or planning to get pregnant.
Breast Feeding
It is unsafe to use Exena S 25mg/5mg Tablet during breastfeeding because the medicine may pass into breast milk. Consult your doctor for advice. Inform your doctor if you are breastfeeding.
Lungs
It is unknown whether Exena S 25mg/5mg Tablet is safe for patients with lung problems. Notify your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.
Liver
Exena S 25mg/5mg Tablet is used cautiously in patients with liver impairment. Inform your physician about the pre-existing live conditions. Your physician will monitor your liver functions and adjust the dose accordingly.
Alcohol
It is not known whether it is safe to drink alcohol while taking Exena S 25mg/5mg Tablet. Check with your doctor for advice.
Driving
It is unknown whether this medicine affects your ability to drive or use machines.
Side Effects of Exena S 25mg/5mg Tablet
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Serious
- Irregular heartbeat
- Sudden or throbbing headache
- Angioedema ( swelling of the face, mouth, or throat)
- Elevated blood pressure
Common
- Increased heart rate
- Nausea
- Constipation
- Diarrhea
- Dizziness
- Urinary tract infection
- Abdominal pain
- Heartburn
- Burping
- Blurred vision
Word of Advice
Patients with liver, heart, and kidney disorders should take Exena S 25mg/5mg Tablet cautiously and inform the doctor about all the underlying medical conditions and medications that you consume. Avoid using this medication if you are intolerant to lactose sugar.
Do not stop Exena S 25mg/5mg Tablet until your doctor advises. Do not double-dose the medicine to make up for a forgotten dose. Notify your doctor if you experience any serious side effects. Your medical professional will inform you if you need any dose adjustments. Contact your doctor for more information.
FAQs
Q 1. What is the best time of day to take Exena S 25mg/5mg Tablet?
The best time of day to take Exena S 25mg/5mg Tablet can vary depending on the individual and healthcare provider's recommendation. It is generally recommended to follow the prescribed dosage instructions and take medicine at the same time each day for consistency.
Q 2. What should I do if I miss a dose of Exena S 25mg/5mg Tablet?
If you miss a capsule dose, take it as soon as possible. However, if it's close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose of Exena S 25mg/5mg Tablet.
Q 3. Can you take Exena S 25mg/5mg Tablet when pregnant?
It is unsafe to consume this medicine while pregnant. Consult your medical professional regarding the use of Exena S 25mg/5mg Tablet during pregnancy. The potential benefits and risks should be carefully assessed. Your doctor will suggest taking this medicine only if it's necessary.
Q 4. What are the side effects of Exena S 25mg/5mg Tablet?
Common side effects of Exena S 25mg/5mg Tablet include increased blood pressure, headache, dizziness, urinary tract infection, blurred vision, burping, heartburn, and constipation. Contact your doctor if you experience any side effects, and consult your healthcare provider for more information.
Q 5. How to manage the side effects of Exena S 25mg/5mg Tablet?
To manage the side effects of Exena S 25mg/5mg Tablet, follow your doctor's instructions, stay hydrated, and monitor blood pressure and any changes. Report severe side effects to your doctor and inform them about other medications or conditions. Maintain a healthy lifestyle and consult your doctor for personalized guidance.
Fact Box of Exena S 25mg/5mg Tablet
| Molecule Name: Mirabegron + Solifenacin | Therapeutic class: Urology |
Pharmacological class: 1. Beta 3-adrenoceptor agonist 2. Muscarinic receptor antagonists
| Indications: 1. Treatment of overactive bladder (OAB) symptoms. 2. Helps control uncontrollable bladder emptying (urgency incontinence). 3. Reduces sudden urges to urinate. 4. Reduces frequent urination.
|
References
- Astellas Pharma Ltd, Electronic Medicines Compendium (EMC), [Revised on December 2022] [Accessed on 6th June 2023], Mirabegron + Solifenacin-TAB PL-Patient United Kingdom (Great Britain) en - TW366830 (medicines.org.uk)
- Astellas Pharma US, Inc; [Revised on March 2021] [Accessed on 6th June 2023], label (fda.gov)
- Astellas Pharma Ltd, Electronic medicines compendium (EMC), [Revised on Dec 2022] [ Accessed on 20th June 2023], https://www.medicines.org.uk/emc/files/pil.5559.pdf
- GlaxoSmithKline, US Food and Drug Administration, [Revised on April 2010] [ Accessed on 20th June 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/021518s008lbl.pdf
- Goodman & Gilman'sGilman's, The Pharmacological Basis of Therapeutics, Muscarinic receptor agonists and antagonists, 12th edition, 2011, 231.
- J. Goddard, A.N. Turner, Kidney, and urinary tract disease, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 461-523.
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