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Eylea 40mg Injection
Prescription Required
Salt Composition : Aflibercept
Manufacturer : BAYER ZYDUS PHARMA PVT LTD
Origin of Medicine : Germany
1 Vial(s) Of 1ml
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Introduction to Eylea 40mg Injection
Eylea 40mg/ml Injection contains the active constituent Aflibercept. Eylea. It is used to treat eye conditions in which impaired vision occurs due to the formation of an abnormal blood vessel inside the eye. These include wet age-related macular degeneration and diabetic macular edema. In studies, this medication effectively reduces the risk of vision loss and improves visual acuity in people with these conditions. Most patients generally well-tolerated it, and the injection procedure is relatively quick and minimally invasive.
You should avoid this medication, Eylea 40mg/ml Injection, if you have severe hypersensitivity reactions to other anti-VEGF medications. Tell your physician if a person has glaucoma, a history of seeing floaters or flashes, and other illnesses before taking Eylea 40mg/ml Injection. It will not be given if you have an infection or inflammation around the eye. Tell your doctor if surgery was performed recently or planned on your eye before taking this medication.
Uses of Eylea 40mg Injection
- Neovascular (wet) age-related macular degeneration (wet AMD)
- Diabetic macular edema (DME)
- Myopic choroidal neovascularization (myopic CNV)
- Macular edema secondary to retinal vein occlusion
Therapeutic Effects of Eylea 40mg Injection
Eylea 40mg/ml Injection works by binding to and blocking the activity of vascular endothelial growth factor (VEGF). This protein can cause abnormal blood vessel growth and leakage in the eye, leading to vision loss. By inhibiting the activity of VEGF, this medication can help reduce abnormal blood vessel growth and leakage and improve vision in some people with these eye conditions.
Interaction of Eylea 40mg Injection with other drugs
Inform your healthcare provider about all your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Eylea 40mg/ml Injection and reduce effectiveness by causing undesirable side effects.
More Information about Eylea 40mg Injection
- Store in a refrigerator at 2-8°C.
- Do not freeze.
- Protected from light.
- Keep it in its original packaging until it is ready to be used.
- Keep out of the reach of children and pets.
- Should be disposed of properly.
How to consume Eylea 40mg Injection
A healthcare provider will inject Eylea 40mg/ml Injection around the eye in a clinical setting. The dosage and frequency of infusions will vary depending on the patient's medical condition, age, weight, and other factors. A Person should not take a double dose to make up the second dose.
Safety Advices for Eylea 40mg Injection
Pregnancy
There is limited information available that Eylea 40mg/ml Injection is used in pregnancy or not. So women should consult their doctor if they are pregnant or planning to become pregnant before taking this medication.
Breast Feeding
It is unclear whether Eylea 40mg/ml Injection is excreted in human milk. So you should consult a doctor before taking this medication if you are a breastfeeding mother.
Lungs
Patients, after taking Aflibecept, may experience pulmonary adverse events, such as shortness of breath, coughing, and interstitial lung disease. Therefore, patients with pre-existing lung conditions, such as COPD (chronic obstructive pulmonary disease) or asthma, may be at an increased risk of developing pulmonary adverse events when receiving this medication.
Liver
Eylea 40mg/ml Injection is primarily metabolized in the liver, so inform your healthcare provider if you have any liver problems or diseases. This medication may also increase liver enzymes, which can be liver damage sign or inflammation. Patients taking this medication require regular blood tests to monitor liver function.
Alcohol
There is no known interaction between Eylea 40mg/ml Injection and alcohol. But in high amounts, alcohol can worsen the liver-related side effect. So patients should consult the doctor before taking alcohol while taking this medication.
Driving
Eylea 40mg/ml Injection may cause side effects such as blurred vision, affecting a patient's ability to drive or operate heavy machinery. Patients should wait until their vision is normal before driving or operating machinery.
Side Effects of Eylea 40mg Injection
Like all medications, Eylea 40mg/ml Injection cause some side effects, although not every person who takes it will experience them.
Serious:
- Blood clots or stroke
- Heart attack
- Severe bleeding or hemorrhage
- Gastrointestinal perforation (a hole in the stomach or intestine)
- Severe infections
- Hypertensive crisis (a sudden and severe increase in blood pressure)
Common:
- Eye pain, irritation, or redness
- Blurred vision
- Increased tear production
- Sensitivity to light
- Headache
- High blood pressure
- Nasal congestion
- Nausea
- Vomiting
- Diarrhea
- Back pain
- Joint pain
Word of Advice
If you are currently being treated with Aflibercept, it is crucial to notify your healthcare provider immediately if you feel any side effects or have any concerns. For pregnant individuals planning to conceive or breastfeeding, it is essential to consult with your healthcare provider to discuss the potential risks and benefits associated with the treatment. Patients with diabetic retinopathy should be closely monitored during treatment because this medication can worsen the condition.
If you experience symptoms such as eye pain, worsening redness of the eye, reduced or blurry vision, or increased sensitivity to light while undergoing treatment, inform your doctor promptly. Lifestyle changes, including quitting smoking, maintaining a healthy weight, and following a healthy diet, can improve overall health and reduce the risk of cancer-related complications. Emotional support from family, friends, or support groups can help cancer patients manage their treatment challenges.
FAQs
Q 1. How often will I need to receive Eylea 40mg/ml Injection?
The frequency of Eylea 40mg/ml Injection will depend on the specific condition being treated and the patient's response to treatment. For wet AMD, patients typically receive an initial round of injections followed by regular maintenance injections every 4 to 8 weeks.
Q 2. Will I still need to use my eyeglasses or contact lenses after receiving Eylea 40mg/ml Injection treatment?
Yes, receiving Eylea 40mg/ml Injection will not correct refractive errors or cure any underlying eye conditions that may require corrective lenses. Patients should continue to use any prescribed eyeglasses or contact lenses as directed by their healthcare provider.
Q 3. Can I receive local anesthesia before the Eylea 40mg/ml Injection?
Yes, local anesthesia may be used before the Eylea 40mg/ml Injection to help reduce pain and discomfort before the procedure. The anesthesia type will depend on the patient's needs and the healthcare provider's preferences.
Q 4. Can Eylea 40mg/ml Injection cause eye infections?
While rare, there is a small risk of eye infections associated with Eylea 40mg/ml Injection. Patients should report any symptoms of eye infection, such as redness, swelling, pain, or discharge, to their healthcare provider immediately.
Q 5. Can I take Eylea 40mg/ml Injection if I have high blood pressure?
Yes, you can still receive Eylea 40mg/ml Injection if you have high blood pressure. However, it is important to inform your healthcare provider of any existing medical conditions, including high blood pressure, before starting treatment with Eylea 40mg/ml Injection. This is because some patients may experience increased blood pressure as a side effect of the medication.
Q 6. Can I take Eylea 40mg/ml Injection if I have a kidney problem?
If you have kidney problems, informing your healthcare provider before starting treatment with Eylea 40mg/ml Injection is important. While Eylea 40mg/ml Injection is primarily used to treat eye conditions and does not have a direct effect on the kidneys, the medication is cleared from the body through the kidneys. Therefore caution may be needed in patients with impaired kidney function.
Fact Box of Eylea 40mg Injection
Molecule name: Aflibercept | Therapeutic class: Anti-angiogenic agent |
Pharmacological class: VEGF Inhibitor | Indications: 1. Neovascular (wet) age-related macular degeneration (wet AMD) 2. Diabetic macular edema (DME) 3. Myopic choroidal neovascularization (myopic CNV) 4. Macular edema secondary to retinal vein occlusion |
References
- Katzung BG, Trevor AJ. Basic & Clinical Pharmacology, 14th Edition; 2018, 637-654
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, 13th edition, 2018, 1113-114
- Bayer AG, Electronic medicines compendium (EMC), [ Revised on Jan 2021] [ Accessed on 26th April 2023], https://www.medicines.org.uk/emc/files/pil.2879.pdf
- Regeneron Pharmaceuticals, Inc, US Food and Drug Administration, [ Revised on Nov 2011] [ Accessed on 26th April 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/125387lbl.pdf
Disclaimer
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