Gufigest Aqua 25mg Injection is used in the treatment of the following:

• Hormone replacement therapy: Gufigest Aqua 25mg Injection is used along with estrogen to reduce menopausal symptoms.
• Amenorrhea: A condition in which women don’t get their periods for months
• Reduce the risk of uterine cancer

The therapeutic effect of Gufigest Aqua 25mg Injection is to regulate and support various reproductive processes in the body, including the menstrual cycle, fertility treatments, hormone replacement therapy, and pregnancy maintenance. It helps prepare the uterus for potential pregnancy, maintains the uterine lining, prevents contractions that could lead to miscarriage, and contributes to overall hormonal balance. It can also be used in contraception to inhibit ovulation, thicken cervical mucus, and create an unfavourable environment for sperm, thus preventing pregnancy.

Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Gufigest Aqua 25mg Injection, reducing effectiveness by causing undesirable side effects. 

• Stored at controlled room temperature, between 20°C to 25°C (68°F to 77°F).
• Keep away from moisture, heat, and light.
• It should not be frozen.
• Keep away from children and pets.

This injection is given by a healthcare provider. The dosage and frequency will depend on the specific condition being treated.

Gufigest Aqua 25mg Injection causes some side effects like all medications, although not everyone will experience them. 

Serious:

• Allergic reaction
• Swelling
• Painful urination
• Vaginal bleeding
• Depression
• Memory loss
• Breast lumps
• Dark patches on the skin
• Vomiting
• Blood clots

Common:

• Nausea
• Bloating
• Vaginal discharge
• Mood swings
• Frequent urination
• Tiredness

It is important to inform your healthcare provider about any existing medical conditions, including liver or kidney impairment, epilepsy, or cardiovascular diseases. Some individuals may experience hypersensitivity reactions to Gufigest Aqua 25mg Injection, including allergic reactions. Seek immediate medical attention if you develop symptoms such as rash, itching, swelling, or difficulty breathing. It should be used cautiously in individuals with a history of cardiovascular disease, arrhythmias, or those taking other medications that can affect heart rhythm. Pregnant or breastfeeding individuals should seek medical advice before using it.  Do not smoke while taking this medication, as this may increase your chances of a blood clot.

1. Watson Laboratories Inc, US Food and Drug Administration, [Revised on 2007] [Accessed on 12th June 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/017362s104lbl.pdf
2. MP Warren et al., Use of Progesterone in clinical practice, Int J Fertil Womens Med, 1999, 44(2):96-103. [Accessed on 12th June 2023], https://pubmed.ncbi.nlm.nih.gov/10338267/
3. Donald G Stein et al, The case for progesterone, Ann N Y Acad Sci, 2005, 1052:152-69 [Accessed on 12th June 2023], https://pubmed.ncbi.nlm.nih.gov/16024758/
4. Edwards M et al., Progestins, NCBI Bookshelf, [Revised on 2020] [Accessed on 12th June 2023], https://www.ncbi.nlm.nih.gov/books/NBK563211/#_NBK563211_pubdet_
5. Besins Healthcare (UK) Ltd, Electronic Medicines Compendium (EMC) [Revised on 10 May 2022], [Accessed on 12th June 2023],https://www.medicines.org.uk/emc/product/352/pil#gref