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Gufigest SR 400mg Capsule
Last updated on 12 Oct 2026 | 11:30 AM (IST)
₹365
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Introduction
Gufigest SR 400mg Capsule contains the active component Progesterone. It is a hormone that plays a vital role in the female reproductive system and menstrual cycle. It is produced mainly by the ovaries after ovulation, but the placenta can also produce it during pregnancy and in smaller amounts by the adrenal glands. These medications are designed to mimic the natural effect of progesterone in the body. C Hope AQ 50 uses generally include hormone replacement therapy during menopause, menstrual cycle regulation, and support for early pregnancy in specific fertility protocols. Some patients also enquire about affordability and availability through searches like C Hope AQ 50 price under doctor supervision.
Individuals with a known allergy or hypersensitivity to it or its components should avoid this medication. It may not be recommended for individuals with certain medical conditions, such as liver disease, certain types of cancer (e.g., breast cancer, liver cancer), a history of blood clotting disorders, or undiagnosed vaginal bleeding. These conditions can increase the risk of complications or may be exacerbated by Gufigest SR 400mg Capsule.
In some cases, individuals with certain hormonal imbalances, such as uncontrolled hyperthyroidism or poorly managed diabetes, may require careful monitoring or adjustment of their medication regimen when using this treatment.
Uses
Hormone replacement therapy: Gufigest SR 400mg Capsule is used along with estrogen to reduce menopausal symptoms.
Amenorrhea: A condition in which women don’t get their periods for months
Reduce the risk of uterine cancer
How Gufigest SR 400mg Capsule Works
The therapeutic effect of Gufigest SR 400mg Capsule is to regulate and support various reproductive processes in the body, including the menstrual cycle, fertility treatments, hormone replacement therapy, and pregnancy maintenance. It helps prepare the uterus for potential pregnancy, maintains the uterine lining, prevents contractions that could lead to miscarriage, and contributes to overall hormonal balance. It can also be used in contraception to inhibit ovulation, thicken cervical mucus, and create an unfavorable environment for sperm, thus preventing pregnancy.
Interaction of Gufigest SR 400mg Capsule with other drugs
Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Gufigest SR 400mg Capsule, reducing effectiveness by causing undesirable side effects.
Storage Conditions
Stored at controlled room temperature, between 20°C to 25°C (68°F to 77°F).
Keep away from moisture, heat, and light.
It should not be frozen.
Keep away from children and pets.
How to take Gufigest SR 400mg Capsule
Susten SR 400mg Tablet is used orally. The dosage and frequency will depend on the specific condition being treated as decided by the healthcare provider.
Safety advice
Pregnancy
Gufigest SR 400mg Capsule is safe for pregnancy if prescribed by your doctor.
Breast Feeding
Gufigest SR 400mg Capsule is safe while breastfeeding, as it can pass into breast milk and potentially affect the nursing infant.
Lungs
If you have pre-existing lung conditions or respiratory issues, it's important to inform your healthcare provider before taking Gufigest SR 400mg Capsule.
Liver
Gufigest SR 400mg Capsule is generally used cautiously in individuals with liver impairment or liver disease. The medication is metabolized in the liver, and impaired liver function can affect the metabolism and clearance of this medication from the body.
Alcohol
Combining Gufigest SR 400mg Capsule with alcohol is generally not recommended. Alcohol can increase the sedative effects of this medication and may enhance certain side effects, such as drowsiness, dizziness, and impaired coordination.
Driving
Gufigest SR 400mg Capsules can cause side effects that may impair your ability to drive or operate machinery safely. Common side effects are drowsiness, dizziness, and vision changes. These effects can affect your coordination, reaction time, and judgment, making driving unsafe or performing tasks requiring alertness.
Side Effects
Gufigest SR 400mg Capsule causes some side effects like all medications, although not everyone will experience them.
Serious:
Allergic reaction
Swelling
Painful urination
Vaginal bleeding
Depression
Memory loss
Breast lumps
Dark patches on the skin
Vomiting
Blood clots
Common:
Nausea
Bloating
Vaginal discharge
Mood swings
Frequent urination
Tiredness
Expert Tips
Inform your healthcare provider about any existing medical conditions, including liver or kidney problems, epilepsy, or cardiovascular diseases.
Some individuals may develop hypersensitivity reactions to Progesterone NPP; seek immediate help if you notice rash, itching, swelling, or breathing difficulty.
Use this medication cautiously if you have a history of cardiovascular disease or arrhythmias, or if you are taking medicines that may affect heart rhythm.
Pregnant or breastfeeding individuals should consult their doctor before using this medication.
Avoid smoking while taking this medicine, as it may increase the risk of blood clots.
FAQs
Q1.
Can Gufigest SR 400mg Capsule be used for male patients?
While Gufigest SR 400mg Capsule is primarily associated with female reproductive health, it may also have uses in certain male conditions. Your healthcare professional can provide more information on cases where this medication may be prescribed for male patients.
Q2.
Can Gufigest SR 400mg Capsule be used for non-reproductive health conditions?
While Gufigest SR 400mg Capsule is commonly used in reproductive health contexts, emerging studies explore its potential therapeutic applications in various non-reproductive conditions such as neuroprotection, mood disorders, and cardiovascular health. However, the use of this medication for non-reproductive conditions is still being researched, and its efficacy and safety may vary.
Q3.
Can Gufigest SR 400mg Capsule be used for contraception?
Gufigest SR 400mg Capsule can be used as a form of contraception. Discussing contraceptive options with your healthcare professional to determine the most suitable method for you is important.
Q4.
Can Gufigest SR 400mg Capsule be used for fertility treatment in menopausal women?
Gufigest SR 400mg Capsule is commonly used in fertility treatments, but its use in menopausal women for fertility purposes may vary. Depending on the specific circumstances and underlying causes of infertility, your healthcare professional can guide the potential role of this medication in your fertility treatment plan.
Q5.
Can Gufigest SR 400mg Capsule be used to prevent miscarriages?
Gufigest SR 400mg Capsule is often prescribed to support pregnancy and reduce the risk of miscarriage, particularly in cases of Gufigest SR 400mg Capsule deficiency or other factors impacting pregnancy viability. Your healthcare professional can evaluate your situation and determine if this medication is an appropriate intervention for preventing miscarriages.
Q6.
Can Gufigest SR 400mg Capsule affect mood and emotional well-being?
Gufigest SR 400mg Capsule, like any hormone therapy, can potentially impact mood and emotional well-being. While some individuals may experience mood changes or emotional fluctuations while using this medication, others may not. If you have concerns about the effects on your mood or emotional state, discussing them with your healthcare professional is important.
Q7.
What are the common side effects of Gufigest SR 400mg Capsule?
Common side effects of Gufigest SR 400mg Capsule may include fatigue, dizziness, headache, breast tenderness or swelling, bloating, nausea, mood changes, and changes in menstrual bleeding patterns. These side effects are typically mild and transient, and not everyone experiences them.
Fact Box
Molecule name: | Progesterone |
Therapeutic class: | Progestins |
Pharmacological class: | Progestational agent |
Indications: | 1. Gastroparesis 2. Nausea and vomiting 3. Gastroesophageal reflux disease (Acid reflux and heartburn) |
References
Watson Laboratories Inc, US Food and Drug Administration, [Revised on 2007] [Accessed on 12th June 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/017362s104lbl.pdf
MP Warren et al., Use of Gufigest SR 400mg Capsule in clinical practice, Int J Fertil Womens Med, 1999, 44(2):96-103. [Accessed on 12th June 2023], https://pubmed.ncbi.nlm.nih.gov/10338267/
Donald G Stein et al, The case for Gufigest SR 400mg Capsule, Ann N Y Acad Sci, 2005, 1052:152-69 [Accessed on 12th June 2023], https://pubmed.ncbi.nlm.nih.gov/16024758/
Edwards M et al., Progestins, NCBI Bookshelf, [Revised on 2020] [Accessed on 12th June 2023], https://www.ncbi.nlm.nih.gov/books/NBK563211/#_NBK563211_pubdet_
Besins Healthcare (UK) Ltd, Electronic Medicines Compendium (EMC) [Revised on 10 May 2022], [Accessed on 12th June 2023],https://www.medicines.org.uk/emc/product/352/pil#gref
Disclaimer
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Author Details

Written By
Dr. Vikas B S
Pharm D

Reviewed By
Dr. Abhishaanth Prabu
MBBS
Last updated : 12 Oct 2026 | 11:30 AM (IST)

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