• HIV infection
• Chronic hepatitis B virus (HBV) infection

Hepitec 100mg tablet works by inhibiting the reverse transcriptase enzyme of HIV, restricting the replication of the viral genome, and reducing the production of new infectious viral particles. It mainly interferes with reverse transcription and inhibits the spread of HIV.

Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications such as sorbitol and other sugar alcohols (such as xylitol, mannitol, lactitol, or maltitol) and other medicine may interact with Hepitec 100mg tablet and can cause undesirable side effects.

• Keep out of sight and reach of pets and children.
• Store protected from light at a temperature not exceeding 30°C.
• Do not refrigerate.

Take Hepitec 100mg tablet as advised by your physician. Usually, this medicine will be given once a day. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the medicine if your doctor advises you to stop.

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.

Serious

• Signs of osteonecrosis (stiffness in the joints, pain in hip, knee, or shoulder)
• Liver problems (yellowing of whites of eyes and skin, urine turns dark, light-colored stools)
• Muscle weakness
• Heart palpitations
• Tremor (neurological disorder) or hyperactivity

Common

• Headache, dizziness
• Nausea, vomiting
• Diarrhea, stomach pain
• Tiredness, lack of energy
• Muscle pain, joint pain
• Difficulty in sleeping
• Cough, runny nose
• Rash, hair loss

To prevent the spread of HIV infection, avoid sharing needles or syringes, which can transmit HIV-1 infections easily. It's necessary for individuals who use injectable drugs to use sterile needles and syringes and never share them with others. Personal items like toothbrushes, razor blades, or anything that can have blood or body fluids on them should also be avoided. They should not be shared because HIV-1 can be present in blood and certain body fluids, and sharing these items could mainly transmit the virus.

Do not double-dose if you forget the dose. Inform your physician if you have any kidney disorders. Your physician will monitor your kidney condition before starting the treatment and may reduce the dose. Contact your healthcare professional immediately if you experience any side effects.

1. .KD Tripathi, Essentials of Medical Pharmacology, Antiviral drugs, 7th edition, 2013, 808.
2. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Antiviral agents (Nonretroviral), 12th edition, 2011, 1617.
3. Milpharm Limited, Electronic medicines compendium (emc), [ Revised on Sep 2020] [ Accessed on  15th May 2023], https://www.medicines.org.uk/emc/files/pil.7066.pdf
4. ViiV Healthcare, US Food and Drug Administration, [ Revised on Sep 2017] [ Accessed on 15th May 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/020564s37_020596s036lbl.pdf