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Immunorel 0.5gm Injection 10ml

Prescription Required

cold-chain

Salt Composition : Human Normal Immunoglobulin

Manufacturer : RELIANCE LIFE SCIENCES PVT LTD

Origin of Medicine : India

MRP: 1615.11
Price : 1292
You Save : 323 (20%)

1 Vial(s)

Prepaid Only. Non-Returnable

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Introduction to Immunorel 0.5gm Injection 10ml

Immunorel 0.5gm Injection 10ml is an immunostimulant drug containing the active ingredient Human normal immunoglobulin that belongs to the class of immunoglobulin derivatives.  It is used as a replacement therapy for individuals with primary immunodeficiency disorders (PIDs), where the body's immune system cannot produce sufficient antibodies to fight off infections. The medication is also used to modulate or regulate the immune system in certain autoimmune and inflammatory conditions. It can help reduce excessive inflammation and suppress abnormal immune responses.

This drug is contraindicated in individuals with known hypersensitivity or allergy to human immunoglobulin or its components. There is a chance of developing blood clots during the treatment with Immunorel 0.5gm Injection 10ml treatment hence it is recommended to monitor the blood viscosity and ensure adequate hydration. If you have a selective IgA deficiency, there is a risk of developing antibodies against IgA. 

In such cases, normal human immunoglobulin should be used cautiously or avoided altogether. Inform your physician if you have a history of IgA deficiency. After receiving an Immunorel 0.5gm Injection 10ml, it is possible to experience a temporary decrease in the concentration of white blood cells, a condition named as neutropenia (low neutrophil count) which resolves spontaneously within a week.  It is not recommended for children younger than 12 years since the effects of human immunoglobulin in this population are unknown.

The administration of normal human immunoglobulin may interfere with the effectiveness of live attenuated vaccines. It is advisable to avoid live vaccines for a certain period after receiving this drug. The overdose of Immunorel 0.5gm Injection 10ml may lead to fluid overload, particularly in patients with pre-existing heart failure or compromised renal function. 

Patients with such conditions should be carefully monitored during infusion. Inform your doctor of any heart, thyroid, kidney, or liver disease. Your physician may prescribe you a low dose and perform regular blood tests. The use of this medicine during pregnancy or breastfeeding should be discussed with your physician.


Uses of Immunorel 0.5gm Injection 10ml

Uses of Immunorel 0.5gm Injection 10ml:

  • Primary immunodeficiency disease (PID)
  • Chronic inflammatory demyelinating  polyneuropathy (CIDP)
  • Multifocal motor neuropathy

Therapeutic Effects of Immunorel 0.5gm Injection 10ml

Immunorel 0.5gm Injection 10ml works by restoring the immunoglobulin G (IgG) antibodies. It directly binds to the Fc fragment-specific receptors and acts against inflammatory mediators. It induces cell death in B and T cells, eventually reducing inflammation and the severity of infections. It functions by replenishing the antibodies that are lacking in order to combat infections and inflammation. 


Interaction of Immunorel 0.5gm Injection 10ml with other drugs

Inform your physician about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Immunorel 0.5gm Injection 10ml and cause undesirable side effects.The use of human immunoglobulins reduces the effectiveness of some vaccines like mumps, measles,rubella and chickenpox.


More Information about Immunorel 0.5gm Injection 10ml

  • Store Immunorel 0.5gm Injection 10ml in a refrigerator (2°C- 8°C).
  • Do not freeze.

How to consume Immunorel 0.5gm Injection 10ml

Immunorel 0.5gm Injection 10ml is usually administered through a vein (intravenously) by your physician in a hospital setting. It will be infused into your body gradually at first. After then, your doctor might progressively raise the infusion rate.Your physician will decide the correct dosage and duration based on age, body weight, blood viscosity and  other disease conditions. 


Safety Advices for Immunorel 0.5gm Injection 10ml

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Pregnancy

  

Immunorel 0.5gm Injection 10mls will be given by your physician  during pregnancy only if the benefits outweigh the risks. Report to your doctor if you are pregnant, suspecting, or planning for the pregnancy before starting the treatment. 

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Breast Feeding

  

Immunorel 0.5gm Injection 10mls should be taken if it is necessary during breastfeeding as it  is unknown whether Immunorel 0.5gm Injection 10ml is excreted in breast milk Consult your doctor for more advice.

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Lungs

  

It is unknown whether Immunorel 0.5gm Injection 10ml is safe for patients with lung problems. Contact your doctor if you experience any lung-related symptoms.

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Liver

  

Inform your doctor if you have liver disease because Immunorel 0.5gm Injection 10ml should be used cautiously with a liver condition.

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Alcohol

  

It is unknown whether consuming alcohol while taking a Immunorel 0.5gm Injection 10ml is safe. Please speak with your physician.

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Driving

  

Driving vehicles or operating machinery while taking Immunorel 0.5gm Injection 10ml is unsafe because it may cause a lack of coordination and concentration. 


Side Effects of Immunorel 0.5gm Injection 10ml

Side Effects are unwanted symptoms caused by medicines. Although all medicines cause side effects, not everyone gets them.

Serious

  • Severe allergic reaction (rash, itching, swelling of lips, tongue, wheezing, difficulty breathing, low blood pressure with confusion, dizziness, fainting)
  • Meningitis (inflammation of the brain)
  • Respiratory failure
  • Migraine
  • High blood pressure
  • Blood clot in lungs
  • Rupturing of red blood cells

Common

  • Rash
  • Itching
  • Wheezing
  • Difficulty in breathing
  • Swelling of the eyelids
  • Fever
  • Confusion
  • Dizziness
  • Low BP

Word of Advice

If you have a current or past history of a kidney disorder, it is important to inform your physician. They will exercise caution and closely monitor your kidney function during treatment with Immunorel 0.5gm Injection 10ml. Eat a well-balanced diet. You should avoid driving or handling machines if you feel dizzy or tired. The rate of infusion may be connected to some side effects, such as headache, flushing, chills, myalgia, wheezing, tachycardia, lower back pain, nausea, and hypotension. Adherence to the prescribed infusion rate is crucial. Immunorel 0.5gm Injection 10ml may alter some laboratory tests hence it is essential to inform your doctor before screening for any tests. Regular monitoring of urine output and renal function must be followed. 


FAQs

Q 1. How long does it take for Immunorel 0.5gm Injection 10ml to work?

It usually takes 30 to 60 minutes of administration for Immunorel 0.5gm Injection 10ml to start working.

Q 2. What are the common side effects of Immunorel 0.5gm Injection 10ml?

The common side effects of Immunorel 0.5gm Injection 10ml are rash, itching, wheezing, difficulty in breathing, swelling of the eyelids, face, lips, throat, or tongue, extremely low blood pressure with symptoms like dizziness, confusion, fainting, and a fast pulse.

Q 3. How do you know if Immunorel 0.5gm Injection 10ml therapy works for you?

It may take up to 4 weeks of regular Immunorel 0.5gm Injection 10ml therapy to notice a steady improvement in your symptoms. Your healthcare provider will suggest a suitable alternative if you do not notice any changes.

Q 4. What should you not take with Immunorel 0.5gm Injection 10ml?

Avoid receiving live vaccines for measles, mumps, rotavirus, varicella, influenza, and rubella while on treatment with Immunorel 0.5gm Injection 10ml.

Q 5. Who is not eligible for Immunorel 0.5gm Injection 10ml treatment?

Those who have experienced severe allergic responses to immunoglobulin products or any of the components in the past may not be good candidates for this treatment. Additionally, people with specific medical disorders including congestive heart failure, thrombosis, or renal impairment should utilize it with caution. Before taking Immunorel 0.5gm Injection 10ml, expectant moms and nursing mothers should speak with their healthcare professionals.

Q 6. How is Immunorel 0.5gm Injection 10ml administered?

Immunorel 0.5gm Injection 10ml is available as a solution for injection, intended for intravenous administration. Your healthcare provider will calculate the accurate dose and duration of this treatment based on your condition and administer this medication as an intravenous infusion.


Fact Box of Immunorel 0.5gm Injection 10ml

Molecule Name: Human normal immunoglobulin

Therapeutic class:  Immunostimulants

Pharmacological class: Immunoglobulin derivatives

Indications: 

1. Primary immunodeficiency disease (PID)

2. Chronic inflammatory demyelinating  polyneuropathy (CIDP)

3. Multifocal motor neuropathy

Dosage form: Intravenous injections

Habit forming: No


References

  1. Biotest Pharma GmbH, Electronic medicines compendium (EMC), [ Revised on March 2020] [ Accessed on 12/02/2024], https://www.medicines.org.uk/emc/files/pil.576.pdf
  2. Takeda pharmaceuticals USA Inc., US Food & Drug Administration, [Revised on Jan 2024], [Accessed on 12th Feb 2024], https://www.fda.gov/media/70812/download
  3. Octapharma USA Inc., US Food & Drug Administration, [Revised on Mar 2022] [Accessed on 12/02/2024], https://www.fda.gov/media/70911/download
  4. Novaretti MC, Dinardo CL, Immunoglobulin: production, mechanisms of action and formulations, Rev Bras Hematol Hemoter, 2011, 33(5), 377-82, [Accessed on 12th Feb 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415776/pdf/rbhh-33-377.pdf

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