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Intazumab 420mg Injection
Last updated on 31 Mar 2026 | 09:29 AM (IST)
₹21250
MRP: ₹25000
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1 VIAL(s) OF 14ML
Intazumab 420mg Injection
Salt Composition
PERTUZUMABMarketer
INTAS PHARMACEUTICALS LTD
Prepaid Only. Non-Returnable.
15% OFF
₹21250
MRP: ₹25,000.00
Inclusive of all taxes
15% Off
Salt Composition
PERTUZUMABMarketer
INTAS PHARMACEUTICALS LTD
Prepaid Only. Non-Returnable.
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Introduction
Intazumab 420mg Injection is an anticancer medication containing the active constituent Pertuzumab. It is used to treat a type of breast cancer (HER2-positive breast cancer) in combination with other chemotherapy medications. Cancer is a condition in which cells multiply uncontrolled and abnormally.
Intazumab 420mg Injection is not recommended for adolescents and children under 18 years of age. Before taking this medicine, it is vital to inform your doctor if you have or have ever had heart problems or chemotherapy. Use effective birth control during the treatment and for at least six months after the last dose.
Inform your doctor if you have kidney disease before starting with this Pertuzumab injection. Patients with kidney disease should cautiously use this medicine. Make sure you inform your physician of all the medicines, including supplements and herbal medicines, you are taking before you start treatment with this medicine. Do not stop taking this medication without talking to your physician first.
Uses
HER2-positive breast cancer
How Intazumab 420mg Injection works
Intazumab 420mg Injection binds to the human epidermal growth factor receptor 2 (HER2) on cancer cells, potentially destroying or inhibiting cancer cell growth.
Interaction of Intazumab 420mg Injection with other drugs
Inform your healthcare provider about all your medicines, including prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Intazumab 420mg Injection and reduce effectiveness by causing undesirable side effects.
Storage conditions
Keep Intazumab 420mg Injection out of sight and reach of children.
Store in refrigerator at 2°C to 8°C. Do not freeze.
How to use Intazumab 420mg Injection
Intazumab 420mg Injection is available as an injection and administered intravenously once every three weeks. Follow your physician's instructions. Your doctor will determine the frequency and dose of administration because it varies for each person depending on the disease condition. Don’t self-administer.
Safety Advices
Pregnancy
Inform your doctor in case you are pregnant, think you might be pregnant or are planning to get pregnant, as Intazumab 420mg Injection may be unsafe during pregnancy.
Breast Feeding
It may be unsafe to take Intazumab 420mg Injection while breastfeeding. Consult your doctor if you are breastfeeding before taking this medication.
Lungs
It is unknown whether Intazumab 420mg Injection is safe for patients with lung problems. Notify your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.
Liver
Intazumab 420mg Injection is used with caution in patients with liver impairment. Inform your physician about the pre-existing medical conditions. Your physician will monitor your liver functions and adjust the dose accordingly.
Alcohol
It is not known whether it is safe to consume alcohol with Intazumab 420mg Injection. Please consult your doctor.
Driving
Intazumab 420mg Injection may cause dizziness, infusion reaction, and other minor effects. So, avoid driving if you are unwell.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Serious
Severe or persistent diarrhea
Low white blood cell count
Infusion reactions (fever, chills, hot flushes, nausea, headache, joint, and muscle pain)
Severe allergic reactions (swelling of throat and face, difficulty in breathing)
Heart problems (cough, swelling in arms or legs, shortness of breath)
Tumour lysis syndrome (confusion, tiredness, irregular heartbeat, seizures, tingling sensation)
Common
Hair loss
Rash
Sore mouth
Constipation
Poor appetite
Changes in taste
Sleeping troubles
Nose bleeds
Heartburn
Nail problems
Producing more tears
Feeling dizzy
Dry and itchy skin
Ear, nose, or throat infection.
Expert tips
Intazumab 420mg Injection can cause heart-related problems such as heart failure, irregular heartbeats, and uncontrolled high blood pressure.
Inform your doctor about your medical history before starting treatment.
If you experience any of the above symptoms, consult your doctor immediately.
Use effective contraception during treatment.
Continue using contraception for six months after stopping the treatment.
FAQs
Q1.
Does Intazumab 420mg Injection cause any heart problems?
Intazumab 420mg Injection can damage the heart muscle and increase the risk of heart problems. Notify your doctor if you have any history of heart problems.
Q2.
Should I use contraception even after the treatment with Intazumab 420mg Injection?
Yes, using contraception during and after treatment with Intazumab 420mg Injection for at least six months is necessary.
Q3.
Can Intazumab 420mg Injection be self-administered?
No, Intazumab 420mg Injection should not be self-administered and must be given only under the supervision of a healthcare professional.
Q4.
What should I tell my doctor before taking the Intazumab 420mg Injection?
Inform your doctor about the history of your high blood pressure, irregular heartbeat, heart failure, and other heart-related problems.
Q5.
Is it okay to take new medication while taking Intazumab 420mg Injection?
Inform your doctor about the list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use because certain medications may interact with Intazumab 420mg Injection and reduce effectiveness by causing undesirable side effects.
Fact Box
Molecule name | Pertuzumab |
Therapeutic class | Antineoplastics |
Pharmacological class | Monoclonal antibody (mAb) |
Indications | Treatment of HER2-positive breast cancer |
References
Roche Products Ltd, Electronic medicines compendium (emc), [Revised on January 2022] [ Accessed on 15 March 2023], https://www.medicines.org.uk/emc/files/pil.2993.pdf
Komal Jhaveri, Francisco J Esteva; Pertuzumab in the treatment of HER2+ breast cancer; Journal of the National Comprehensive Cancer Network; Published on April 2014; Accessed on 15 March 2023; https://pubmed.ncbi.nlm.nih.gov/24717573/
Kei Ishii; Pertuzumab in the treatment of HER2-positive breast cancer: An evidence-based review of its safety, efficacy, and place in therapy; [Published online on 31st Oct 2019];[Accessed on 21st Feb 2023]; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827570
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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Author Details
Written By
Dr. Vikas B S
Pharm D
Reviewed By
Dr. Abhishaanth Prabu
MBBS
Last updated : 31 Mar 2026 | 09:29 AM (IST)
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