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IrinoSYM 100 Injection
Last updated on 31 Mar 2026 | 09:29 AM (IST)
₹1182
MRP: ₹4218.75
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Introduction
IrinoSYM injection composition includes the active ingredient Irinotecan hydrochloride trihydrate, belonging to the class of anti-cancer medicines or cytostatics. It is primarily used for IrinoSYM for colorectal cancer, specifically advanced colon and rectal cancers in adults. This medication may be prescribed alone or in combination with other chemotherapeutic agents to maximize effectiveness.
The IrinoSYM injection dosage depends on the patient’s condition, weight, and treatment plan. Healthcare providers may consider alternatives such as IrinoSYM 100 mg substitute if required. Many patients compare IrinoSYM vs Camptosar to understand differences in effectiveness, side effects, and administration methods.
IrinoSYM 100 mg injection reviews often highlight its efficacy in managing colorectal cancer while noting potential side effects that need careful monitoring. The IrinoSYM 100 mg injection price may vary across pharmacies and regions, so it is recommended to check with trusted healthcare providers before purchase.
Uses
IrinoSYM 100 injection uses are
the Treatment of metastatic cancer of the colon and rectum (large intestine).
How IrinoSYM 100 Injection Works
IrinoSYM 100 Injection works by converting its active metabolite with the help of liver enzymes and inhibits the Topoisomerase I enzyme. This causes damage to the DNA synthesis and its replication, thus preventing the cancer cells from growing and spreading.
Interaction of IrinoSYM 100 Injection with other drugs
Inform your doctor about any prescribed medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products that you are taking or have taken before the treatment. Certain medications tend to interact with IrinoSYM 100 Injection and can cause potential side effects.
Storage Conditions
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Do not freeze.
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Store protected from light at a temperature not exceeding 25°C.
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Keep this medicine away from the sight and reach of children.
How to Use IrinoSYM 100 Injection
Take this medicine exactly as prescribed. Your healthcare professional administers it into your vein. Do not self-administer. Your physician will recommend a DNA test before taking this medicine. The dose depends on your age, size, and medical condition.
Safety Advices
Pregnancy
It is unsafe to take this medicine during pregnancy as it might harm the foetus. Consult doctor for more information.
Breast Feeding
It is unsafe to use during breastfeeding as IrinoSYM 100 Injection, and its metabolites are found in human milk. It must be discontinued for the duration of therapy. Consult your doctor for advice.
Lungs
It is unknown whether it is safe to administer IrinoSYM 100 Injection in patients with lung disorders. Please consult your doctor for more advice.
Liver
IrinoSYM 100 Injection is used with caution in patients with liver impairment. Inform your physician before starting treatment if you have liver disease or jaundice. Your physician will monitor your liver functions and adjust the dose accordingly.
Alcohol
It is unknown whether it is safe to drink alcohol while taking IrinoSYM 100 Injection. Check with your doctor for advice.
Driving
You may feel dizzy or tired for 24 hours after taking this medicine. Do not use any tools or drive during treatment with IrinoSYM 100 Injection.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. IrinoSYM side effects are
Serious:
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Early and late diarrhea
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Allergic reactions
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Kidney impairment
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Lung problems
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Low levels of RBC, WBC, and platelets in the blood
Common:
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Nausea, vomiting, abdominal pain
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Constipation
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Diarrhea
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Anemia
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Pain
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Fatigue
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Fever, infections including sepsis
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Abnormal bilirubin levels
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Hair loss
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Weight loss
Expert tips
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Diarrhea is often the first sign of IrinoSYM 100 Injection.
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It may be serious if it starts more than 24 hours after taking the medication and requires immediate treatment and close supervision.
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If untreated, diarrhea can cause dehydration and dangerous chemical imbalances that may be life-threatening.
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Avoid using laxatives and stool softeners while on this medication.
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Drink plenty of water or rehydration fluids promptly and take antidiarrheal treatment like loperamide.
FAQs
Q1.
Do you always lose your hair with IrinoSYM 100 Injection?
Hair loss is common with IrinoSYM 100 Injection. It usually starts 3-4 weeks after the first dose of this medication.
Q2.
Does IrinoSYM 100 Injection cause liver damage?
IrinoSYM 100 Injection may cause liver impairment or damage. Inform your physician before starting treatment if you have liver disease or jaundice.
Q3.
What happens if IrinoSYM 100 Injection is taken in more than recommended dose?
If IrinoSYM 100 Injection is taken in more than the recommended doses, it can cause severe blood disorders and diarrhea.
Q4.
Which is the best area to administer IrinoSYM 100 Injection?
IrinoSYM 100 Injection will be administered into the vein under strict medical supervision. Do not self-administer.
Q5.
What measures can be taken to avoid diarrhea when using IrinoSYM 100 Injection?
Drink large amounts of water and rehydration fluids to prevent diarrhea. It is advised to take antidiarrheal medicines, including loperamide.
Fact Box
|
Molecule name |
Irinotecan |
|
Therapeutic class |
Antineoplastics |
|
Pharmacological class |
Topoisomerase I inhibitors |
|
Indications |
Colon and rectum cancer (large intestine cancer) |
References
1. Accord Healthcare Limited, Electronic Medicines Compendium (EMC), [Revised on June 2022] [Accessed on 24 Nov 2022], https://www.medicines.org.uk/emc/files/pil.7318.pdf
2. Pharmacia & Upjohn Co, US Food & Drug Administration, [Revised on Dec 2014] [Accessed on 24 Nov 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/020571s048lbl.pdf
3 I.D. Penman, C.W. Lees, Alimentary Tract and Pancreatic Disease, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 837-920.
4. Edward Chu, Cancer Chemotherapy, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976.
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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Author Details

Written By
P. Thirumal Reddy
B. Pharm

Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 31 Mar 2026 | 09:29 AM (IST)

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