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  3. IrinoSYM 100 Injection
Direct from Manufacturer

Sourced from:Direct from Manufacturer

Substitutes

Irilieva 100mg Injection

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Irnotop 100mg Injection

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₹ 861.00/injection

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Quick summary
Quick Summary

IrinoSYM 100 Injection

Prescription Required
irinotecan
Written By:P. Thirumal ReddyB. Pharm Reviewed By:Dr. Tejashwin AdigaMBBS

Last updated on 31 Mar 2026 | 09:29 AM (IST)

₹1182

MRP: ₹4218.75

(You Save ₹3036.75)

1 VIAL(s)

Direct from Manufacturer

Sourced from:Direct from Manufacturer

72% OFF
IrinoSYM 100 Injection
Preview
4.8 ⭐️ On Google

IrinoSYM 100 Injection


Prescription Required
Required

Salt Composition

IRINOTECAN

Marketer

SYMBION LIFE SCIENCE

72% OFF

IrinoSYM 100 Injection
Preview
We are Rated 4.8 ⭐️ On Google

₹1182

MRP: ₹4,218.75

Inclusive of all taxes

72% Off

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1 Vial(s)

1 Vial(s)

₹ 1182.0/Unit

1 VIAL(s)


Prescription Required
Prescription Required

Salt Composition

IRINOTECAN

Marketer

SYMBION LIFE SCIENCE


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Order before timer ends to ensure your medicine is dispatched at...

Substitutes

Irilieva 100mg Injection

Allieva Pharma ...

₹ 704.00/injection

40% cheaper

Irinozee 100mg Injection

ZEE LABORATORIE...

₹ 844.00/injection

28% cheaper

Irnotop 100mg Injection

METTA LIFE SCIE...

₹ 861.00/injection

27% cheaper

Irinotel 100mg Injection

FRESENIUS KABI ...

₹ 891.00/injection

24% cheaper

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Introduction

IrinoSYM injection composition includes the active ingredient Irinotecan hydrochloride trihydrate, belonging to the class of anti-cancer medicines or cytostatics. It is primarily used for IrinoSYM for colorectal cancer, specifically advanced colon and rectal cancers in adults. This medication may be prescribed alone or in combination with other chemotherapeutic agents to maximize effectiveness.

The IrinoSYM injection dosage depends on the patient’s condition, weight, and treatment plan. Healthcare providers may consider alternatives such as IrinoSYM 100 mg substitute if required. Many patients compare IrinoSYM vs Camptosar to understand differences in effectiveness, side effects, and administration methods.

IrinoSYM 100 mg injection reviews often highlight its efficacy in managing colorectal cancer while noting potential side effects that need careful monitoring. The IrinoSYM 100 mg injection price may vary across pharmacies and regions, so it is recommended to check with trusted healthcare providers before purchase.

Uses

IrinoSYM 100 injection uses are  

the Treatment of metastatic cancer of the colon and rectum (large intestine).

How IrinoSYM 100 Injection Works

IrinoSYM 100 Injection works by converting its active metabolite with the help of liver enzymes and inhibits the Topoisomerase I enzyme. This causes damage to the DNA synthesis and its replication, thus preventing the cancer cells from growing and spreading.

Interaction of IrinoSYM 100 Injection with other drugs

Inform your doctor about any prescribed medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products that you are taking or have taken before the treatment. Certain medications tend to interact with IrinoSYM 100 Injection and can cause potential side effects.

Storage Conditions

  • Do not freeze.

  • Store protected from light at a temperature not exceeding 25°C.

  • Keep this medicine away from the sight and reach of children.

How to Use IrinoSYM 100 Injection

Take this medicine exactly as prescribed. Your healthcare professional administers it into your vein. Do not self-administer. Your physician will recommend a DNA test before taking this medicine. The dose depends on your age, size, and medical condition.

Safety Advices

Pregnancy-Unsafe

Pregnancy

Unsafe

It is unsafe to take this medicine during pregnancy as it might harm the foetus. Consult doctor for more information.

Breast Feeding-Unsafe

Breast Feeding

Unsafe

It is unsafe to use during breastfeeding as IrinoSYM 100 Injection, and its metabolites are found in human milk. It must be discontinued for the duration of therapy. Consult your doctor for advice.

Lungs-Consult Your Doctor

Lungs

Consult Your Doctor

It is unknown whether it is safe to administer IrinoSYM 100 Injection in patients with lung disorders. Please consult your doctor for more advice.

Liver-Consult Your Doctor

Liver

Consult Your Doctor

IrinoSYM 100 Injection is used with caution in patients with liver impairment. Inform your physician before starting treatment if you have liver disease or jaundice. Your physician will monitor your liver functions and adjust the dose accordingly.

Alcohol-Consult Your Doctor

Alcohol

Consult Your Doctor

It is unknown whether it is safe to drink alcohol while taking IrinoSYM 100 Injection. Check with your doctor for advice.

Driving-Unsafe

Driving

Unsafe

You may feel dizzy or tired for 24 hours after taking this medicine. Do not use any tools or drive during treatment with IrinoSYM 100 Injection.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. IrinoSYM side effects are 

Serious:

  • Early and late diarrhea

  • Allergic reactions

  • Kidney impairment

  • Lung problems

  • Low levels of RBC, WBC, and platelets in the blood

Common:

  • Nausea, vomiting, abdominal pain

  • Constipation

  • Diarrhea

  • Anemia

  • Pain

  • Fatigue

  • Fever, infections including sepsis

  • Abnormal bilirubin levels

  • Hair loss

  • Weight loss

Expert tips

  • Diarrhea is often the first sign of IrinoSYM 100 Injection.

  • It may be serious if it starts more than 24 hours after taking the medication and requires immediate treatment and close supervision.

  • If untreated, diarrhea can cause dehydration and dangerous chemical imbalances that may be life-threatening.

  • Avoid using laxatives and stool softeners while on this medication.

  • Drink plenty of water or rehydration fluids promptly and take antidiarrheal treatment like loperamide.

FAQs

Q1.

Do you always lose your hair with IrinoSYM 100 Injection?

Hair loss is common with IrinoSYM 100 Injection. It usually starts 3-4 weeks after the first dose of this medication.

Q2.

Does IrinoSYM 100 Injection cause liver damage?

IrinoSYM 100 Injection may cause liver impairment or damage. Inform your physician before starting treatment if you have liver disease or jaundice.

Q3.

What happens if IrinoSYM 100 Injection is taken in more than recommended dose?

If IrinoSYM 100 Injection is taken in more than the recommended doses, it can cause severe blood disorders and diarrhea.

Q4.

Which is the best area to administer IrinoSYM 100 Injection?

IrinoSYM 100 Injection will be administered into the vein under strict medical supervision. Do not self-administer.

Q5.

What measures can be taken to avoid diarrhea when using IrinoSYM 100 Injection?

Drink large amounts of water and rehydration fluids to prevent diarrhea. It is advised to take antidiarrheal medicines, including loperamide.

Fact Box

Molecule name

Irinotecan

Therapeutic class

Antineoplastics

Pharmacological class

 Topoisomerase I inhibitors

Indications

 Colon and rectum cancer (large intestine cancer)

 

References

1. Accord Healthcare Limited, Electronic Medicines Compendium (EMC), [Revised on June 2022] [Accessed on 24 Nov 2022], https://www.medicines.org.uk/emc/files/pil.7318.pdf

2. Pharmacia & Upjohn Co, US Food & Drug Administration, [Revised on Dec 2014] [Accessed on 24 Nov 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/020571s048lbl.pdf

3 I.D. Penman, C.W. Lees, Alimentary Tract and Pancreatic Disease, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 837-920.

4. Edward Chu, Cancer Chemotherapy, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976.

Disclaimer

MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.

Did you find this information helpful?

Author Details
P. Thirumal Reddy

Written By

P. Thirumal Reddy

B. Pharm


Dr. Tejashwin Adiga

Reviewed By

Dr. Tejashwin Adiga

MBBS


Last updated : 31 Mar 2026 | 09:29 AM (IST)

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