LAPAHOPE 250MG TABLET 30'S

Introduction:

Lapahope 250mg Tablet consists of the active ingredient Lapatinib. It is indicated in combination with other medicines to treat advanced breast cancer in whom hormonal therapy is required. It is active against the rapidly spreading cancer cells that produce large quantities of a protein called human epidermal growth receptor – 2 and cells that are sensitive to hormones. 

Side effects of Lapahope 250mg Tablet include tiredness, stomach pain, diarrhea, heart problems, etc. Report to your physician right away at the first sign of diarrhea to prevent dehydration and other complications. If you experience diarrhea while taking this medicine, drink plenty of fluids, eat low-fat, high protein foods, avoid milk and milk products and herbal supplements. 

Uses of Lapahope 250mg Tablet:

• Treatment of advanced breast cancer

How Lapahope 250mg Tablet works:

Lapahope 250mg Tablet acts against the enzyme called tyrosine kinase and interrupts in the signaling of Epidermal growth factor and HER2 receptors expressed by the breast cancer cells. It slows down the progression of cancer cells and kills them.

Interaction with other drugs:

Inform your doctor about any medications you are taking or have taken before the treatment.

More Information:

Store below 30˚C and protected from light.

References:

1. GlaxoSmithKline Pharmaceuticals Ltd., [Revised on Jan 2015] [Accessed on 24th Jul 2021], https://india-pharma.gsk.com/media/701378/tykerb-tablets.pdf
2. Novartis Pharmaceuticals UK Ltd., Electronic Medicines Compendium (EMC), [Revised on Oct 2020] [Accessed on 21st Jul 2021], https://www.medicines.org.uk/emc/files/pil.6292.pdf
3. GlaxoSmithKline, US Food & Drug Administration, [Accessed on 24th Jul 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/022059s007lbl.pdf
4. Edward Chu, Cancer Chemotherapy, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976.
5. KD Tripathi, Anticancer Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019, 915-936.

How to use Lapahope 250mg Tablet:

Swallow the tablet with water at the same time each day.

Safety Advice:

Pregnancy:

Inform your physician before starting this treatment if you are pregnant or think you might be pregnant. 

Breastfeeding: 

Consult your physician for advice before taking this medicine if you are a breastfeeding mother.

Liver:

Inform your physician before starting this treatment if you have liver diseases. Your physician will prescribe according to your condition.

Kidney:

Inform your physician before starting this treatment if you have kidney diseases. Your physician will prescribe according to your condition.

Driving: 

This medicine could probably affect your ability to drive or perform activities that require focus. Exercise caution while driving or using machines.

Others:

• Consult your physician and use a reliable method of contraception to avoid becoming pregnant during this treatment.
• Inform your physician if you have problems like lung disease, heart disease or diarrhea.
• Your physician will conduct tests before starting this treatment to ensure that your heart is working properly.
• Inform your physician if you experience allergic reactions to Lapatinib or its ingredients.

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

Serious:

• Severe allergic reactions
• Persistent diarrhea
• Skin rash
• Heart problems

Common:

• Loss of appetite
• Nausea, vomiting
• Tiredness, weakness
• Indigestion
• Constipation
• Sore mouth or mouth ulcers
• Stomach pain
• Trouble sleeping
• Back pain
• Pain in the hands and feet
• Joint or back pain
• Cough, breathlessness
• Headache
• Nose bleed
• Hot flush
• Unusual hair loss
• Dry skin and itching