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Letrolive 2.5mg Tablet
Last updated on 26 Sep 2026 | 08:41 AM (IST)
₹237
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₹237
MRP: ₹334.00
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Introduction
Letrolive 2.5mg Tablet is an anti-cancer drug that belongs to the aromatase inhibitor class. It is indicated as a supportive therapy after the main therapy or first-line therapy for postmenopausal women with early and advanced breast cancer whose tumors are hormone receptor-positive. Since high levels of estrogen are known to trigger breast cancer, this medicine reduces estrogen levels by blocking the enzyme (aromatase) involved in estrogen production. This action aims to slow down or stop the growth and/or spreading of the cancer to other body parts, aligning with Letrolive 2.5mg uses in clinical practice.
If you have not attained menopause yet, inform your physician, as this medicine does not work for premenopausal women. Since Letrolive 2.5mg reduces the levels of female reproductive hormones, it is not advised for menstruating women, as it can cause fertility issues. It is also important to monitor your cholesterol levels, as this medication tends to elevate them. Additionally, Letrolive 2.5mg could decrease bone mineral density, so it is recommended to monitor your bone parameters regularly in consultation with your physician.
During treatment with Letrolive 2.5mg, it is advised to use effective birth control and continue its use for at least 3 weeks after the last dose.
For those looking to know the Letrolive 2.5mg price, it can vary depending on location and pharmacy. Many people also want to buy Letrolive 2.5mg online from reputable sources to ensure the medication's authenticity. If Letrolive 2.5mg is not suitable for you, a Letrolive tablet substitute may be available, but always consult your doctor before considering alternatives.
Uses
First and second-line treatment of postmenopausal women with hormone receptor-positive breast cancer.
Supportive to standard treatment for postmenopausal women with early breast cancer.
Treatment for unknown advanced breast cancer in postmenopausal women.
Extended supportive therapy for postmenopausal women with early breast cancer who have already taken other anti-cancer medication.
How Letrolive 2.5mg Tablet Works
The growth of some cancers of breasts are stimulated by estrogens. Letrolive 2.5mg Tablet is a nonsteroidal compound that inhibits estrogen production by blocking the enzyme aromatase. This medicine reduces the tumor size and stops or slows the progression of the disease, avoiding the reoccurring of early-stage breast cancer and improving the survival rate.
Interaction of Letrolive 2.5mg Tablet with other drugs
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, or herbal products you take or have taken before the treatment. Certain medications like tamoxifen and others may interact with Letrolive 2.5mg Tablets and cause undesirable side effects.
Storage conditions
Keep the tablets away from the reach of children and pets.
Store Letrolive 2.5mg Tablet at an optimal temperature not exceeding 25°C.
How to take Letrolive 2.5mg Tablet
It is advised to consume Letrolive 2.5mg Tablet exactly as your doctor prescribes. It can be consumed with or without food and should be swallowed with a glass of water. Letrolive 2.5mg Tablet can be taken with or without food. It is better to take the tablet at a fixed time. Do not break, chew or crush the tablet.
Safety Advices
Pregnancy
Letrolive 2.5mg Tablet are highly unsafe during pregnancy because they may cause harm to the unborn baby. It is better to discuss with a doctor the use of an effective contraceptive method during the Letrolive 2.5mg Tablet treatment if you still have the potential to become pregnant. It is recommended to consult your physician if you are pregnant already or suspect pregnancy.
Breast Feeding
It is not safe to breastfeed your baby when you are taking a Letrolive 2.5mg Tablet. It is advised to avoid breastfeeding for at least three weeks after the last dose of the medicine.
Lungs
Certain lung diseases can occur while using Letrolive 2.5mg Tablet. Consult your doctor if you have lung diseases.
Liver
Inform your physician if you have liver disease, as the Letrolive 2.5mg Tablets are not recommended for patients with severe liver disease. Dose adjustment may be required.
Alcohol
It is not recommended to consume alcohol while you are on the treatment with a Letrolive 2.5mg Tablet as it may cause serious complications.
Driving
Caution is required while driving and operating machinery when you take a Letrolive 2.5mg Tablet causes dizziness, sleepiness, and tiredness.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Letrolive 2.5mg side effects are
Serious
Decreased red blood cells
Decreased bone mineral density
Fluid buildup in lungs
Common
Swelling in the face, eyes, feet, and legs
Hot sweats and excessive sweating
Hypercholesterolemia (high cholesterol)
Constipation
Heart papilation
Hypertension
Diarrhea
Loss of appetite
Nausea and Vomiting
Muscle pain, bone pain, and joint stiffness
Dizziness, tiredness, and sleepiness
Breathing difficulty
Arthralgia.
Expert tips
Notify your doctor if you have hypersensitivity, as this medication is contraindicated in such cases.
Inform your physician if you have osteoporosis or bone fractures, as Letrolive 2.5mg Tablet may reduce bone mineral density and requires periodic monitoring.
Discuss with your doctor if you are planning pregnancy, since this medicine can affect reproductive potential and may cause fertility issues.
Do not use this medicine if you are still menstruating and have not yet reached menopause.
Report to your doctor if you are intolerant to any form of sugar, as Letrolive 2.5mg Tablet Tablet contains lactose, and skip missed doses without doubling the next one.
FAQs
Q1.
Can a Letrolive 2.5mg Tablet cause mood changes?
Mood changes, such as depression or anxiety, are not common side effects of Letrolive 2.5mg Tablet. However, if you experience any changes in mood while taking a Letrolive 2.5mg Tablet , it's important to talk to your doctor.
Q2.
Is it better to take a Letrolive 2.5mg Tablet in the morning or at night?
You can take a Letrolive 2.5mg Tablet in the morning, midday, or evening with or without food, but you should take it at about the same time each day.
Q3.
How often should I have my bone density checked while taking a Letrolive 2.5mg Tablet?
Letrolive 2.5mg Tablets can increase the risk of bone fractures in some people, so it's important to have regular bone density checks while taking the medication. Your doctor will recommend how often you should have these checks.
Q4.
How long is the Letrolive 2.5mg Tablet taken for?
The length of time a person takes a Letrolive 2.5mg Tablet depends on their individual situation and the recommendation of their doctor. Treatment may last for several years.
Fact Box
Molecule name | Letrozole |
Therapeutic class | Aromatase inhibitor |
Pharmacological class | Anti-neoplastic drug |
Indications | Treatment for early breast cancer and postmenopausal women |
References
Ranbaxy (UK) Limited a Sun Pharmaceutical Company, [Revised on December 2022], [Accessed on January 2024], https://www.medicines.org.uk/emc/files/pil.9722.pdf
Novartis Pharmaceuticals Corporation, [Revised on May 2020], [Accessed on 22th Mar 2023], https://www.novartis.com/us-en/sites/novartis_us/files/Femara.pdf?TB_iframe=true
HIGHLIGHTS OF PRESCRIBING INFORMATION. (n.d.). [online] www.accessdata.fda.gov. Available at: https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/020726s027lbl.pdf [Accessed on 22th Mar 2023].
Edward Chu, Cancer Chemotherapy, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976.
KD Tripathi, Estrogens, Progestins and Contraceptives, Essentials of Medical Pharmacology, 8th Edition, 2019, 330-353.
Disclaimer
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Author Details
Written By
Dr. Vikas B S
Pharm D
Reviewed By
Dr. Abhishaanth Prabu
MBBS
Last updated : 26 Sep 2026 | 08:41 AM (IST)
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