• First and second-line treatment of postmenopausal women with hormone receptor-positive breast cancer.
• Supportive to standard treatment for postmenopausal women with early breast cancer.
• Treatment for unknown advanced breast cancer in postmenopausal women.
• Extended supportive therapy for postmenopausal women with early breast cancer who have already taken other anti-cancer medication.

The growth of some cancers of breasts are stimulated by estrogens. Letrovin 2.5mg Tablet is a nonsteroidal compound that inhibits estrogen production by blocking the enzyme aromatase. This medicine reduces the tumor size and stops or slows the progression of the disease, avoiding the reoccurring of early-stage breast cancer and improving the survival rate.

Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, or herbal products you take or have taken before the  treatment. Certain medications like tamoxifen and others may interact with Letrovin 2.5mg Tablets  and cause undesirable side effects.

• Keep the tablets away from the reach of children and pets.
• Store Letrovin 2.5mg Tablet  at an optimal temperature not exceeding 25°C.

It is advised to consume Letrovin 2.5mg Tablets exactly as your doctor prescribes. It can be consumed with or without food and should be swallowed with a glass of water. Letrovin 2.5mg Tablet  can be taken with or without food. It is better to take the tablet at a fixed time. Do not break, chew or crush the tablet.

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

 Serious

• Decreased red blood cells
• Decreased bone mineral density
• Fluid buildup in lungs

Common

• Swelling in the face, eyes, feet, and legs
• Hot sweats and excessive sweating
• Hypercholesterolemia (high cholesterol)
• Constipation
• Heart papilation
• Hypertension
• Diarrhea
• Loss of appetite
• Nausea and Vomiting
• Muscle pain, bone pain, and joint stiffness
• Dizziness, tiredness, and sleepiness
• Breathing difficulty
• Arthralgia

Notify your doctor if you have hypersensitivity because this medication is contraindicated to such a medical condition. Inform your physician if you have osteoporosis or bone fractures, and periodic monitoring of bone mineral density is required while you are on Letrovin 2.5mg Tablet because this medicine can cause a decrease in the bone mineral density. Discuss with your doctor if you are planning for pregnancy, as this medicine shall impact the reproductive potential and might lead to fertility issues. Do not consume this medicine if you are still menstruating and have not yet gone through menopause. Report to your doctor if you are tolerant to any forms of sugar, as Letrovin 2.5mg Tablet  Tablet contains lactose ingredients. If you missed a dose, do not take a double dose for the forgotten dose. Skip the missed dose and go with a regular schedule.

1. Ranbaxy (UK) Limited a Sun Pharmaceutical Company, [Revised on December 2022], [Accessed on January 2024], https://www.medicines.org.uk/emc/files/pil.9722.pdf
2. Novartis Pharmaceuticals Corporation, [Revised on May 2020], [Accessed on 22th Mar 2023], https://www.novartis.com/us-en/sites/novartis_us/files/Femara.pdf?TB_iframe=true
3. HIGHLIGHTS OF PRESCRIBING INFORMATION. (n.d.). [online] www.accessdata.fda.gov. Available at: https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/020726s027lbl.pdf [Accessed on 22th Mar 2023].
4. Edward Chu, Cancer Chemotherapy, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976.
5. KD Tripathi, Estrogens, Progestins and Contraceptives, Essentials of Medical Pharmacology, 8th Edition, 2019, 330-353.