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Lezopure 1.5gm Injection
Last updated on 31 Mar 2026 | 09:31 AM (IST)
₹206
MRP: ₹257.81
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Lezopure 1.5gm Injection
Salt Composition
CEFOPERAZONE,SULBACTAMMarketer
SRIMED PHARMACEUTICAL PVT LTD
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MRP: ₹257.81
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Introduction to Lezopure 1.5gm Injection
Lezopure 1.5gm injection contains two active ingredients in one injection. One of the active substances is Cefoperazone, which belongs to the group of medications called third-generation cephalosporin antibiotics. The other active substance is Sulbactam belonging to the group of medications called beta-lactamase inhibitors. This combination is effective against a wide range of bacteria and this drug is commonly used to treat serious infections such as urinary tract infections, respiratory tract infections, intra-abdominal infections, septicemia, meningitis, skin infections, bone infections, and endometritis.
This drug is contraindicated in individuals with known hypersensitivity or allergy to it or its component. Report your physician if you are allergic to any antibiotic group. Consumption of alcohol (including alcoholic beverages, medications containing alcohol, mouthwashes, or food preparations) during and up to the fifth day after administration can result in a disulfiram-like reaction. This reaction can cause flushing, sweating, headache, and an increased heart rate. It is important to avoid alcohol during this period.
Notify your doctor if you have severe or bloody stools while taking Lezopure 1.5gm injection. Before taking this medicine, talk to your doctor if you have liver disorders, bowel diseases, or clotting disorders. This drug should be taken only if it is necessary during pregnancy. As this medicine passes poorly into the breast milk of nursing mothers, caution should be exercised during breastfeeding. It is necessary to consult this with your physician for more advice.
Uses of Lezopure 1.5gm Injection
- Respiratory Tract Infections
- Urinary Tract Infections
- Intra-abdominal Infections
- Septicemia
- Meningitis
- Skin and Soft Tissue Infections
- Bone and Joint Infections
- Endometritis
Therapeutic Effects of Lezopure 1.5gm Injection
Cefoperazone is an antibiotic that works by interfering with bacterial cell wall synthesis, leading to the destruction of the bacteria. Sulbactam, the beta-lactamase inhibitor, helps inactivate the beta-lactamase enzymes produced by certain bacteria. This prevents the breakdown of cefoperazone by these enzymes, enhancing its effectiveness against resistant bacteria.
Interaction of Lezopure 1.5gm Injection with other drugs
Inform your physician about all your medicines, including prescription, over-the-counter, vaccinations, nutritional and vitamin supplements, and herbal products. Certain medications may interact with the effects of Lezopure 1.5gm injection and reduce its effectiveness by causing undesirable side effects.
More Information about Lezopure 1.5gm Injection
- Store Lezopure 1.5gm injection at temperatures not exceeding 25°C
- Keep the Injection away from the reach of children and pets.
How to consume Lezopure 1.5gm Injection
Do not self-administer the Lezopure 1.5gm injection. Your doctor will decide the duration and dose of your treatment based on the disease severity and other factors. It will be given as an intravenous infusion or intramuscular Injection, and you will be monitored carefully for unwanted side effects.
Safety Advice for Lezopure 1.5gm Injection
Breast Feeding
Breastfeeding is not recommended in patients taking Lezopure 1.5gm injection because the medicine passes into the breast milk in small amounts and harms the baby. Caution is advised in these conditions.
Alcohol
Patients taking Lezopure 1.5gm injection should be cautioned about consuming alcoholic beverages during treatment and for several days afterward. Consult your doctor for more advice.
Liver
It is unknown whether Lezopure 1.5gm injection is safe for patients with liver problems. Notify your physician if you have any liver disease before starting the treatment. Contact your doctor if you experience any liver-related symptoms.
Lungs
Lezopure 1.5gm injection is safe and can be prescribed for patients with lung problems. Consult your physician if you have any lung diseases before starting the treatment.
Driving
Driving vehicles or operating heavy machinery is safe after administering Lezopure 1.5gm injection.
Pregnancy
Lezopure 1.5gm injection should be taken if it is necessary during pregnancy. Report to your doctor if you are pregnant, suspecting, or planning for the pregnancy before starting the treatment.
Side Effects of Lezopure 1.5gm Injection
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Common
- Nausea, vomiting
- Headache
- Diarrhea
- Allergic reactions
- Anemia
- Abnormal liver function
- Injection site reactions
Word of Advice
Maintaining good hand hygiene by washing your hands regularly helps to prevent the spread of infections to others. Do not skip doses or stop the medication suddenly, even if you start feeling better. Completing the full course of treatment is important to effectively treat the infection and prevent the development of antibiotic resistance.
FAQs about Lezopure 1.5gm Injection
Q1.
What is Lezopure 1.5gm injection used for?
Lezopure 1.5gm injection treats various bacterial infections, especially those caused by multidrug-resistant bacteria. It is commonly used for respiratory tract infections, urinary tract infections, skin infections, intra-abdominal infections, and gynecological infections.
Q2.
How does Lezopure 1.5gm injection work?
Cefoperazone is an antibiotic that works by interfering with bacterial cell wall synthesis, leading to the destruction of the bacteria. Sulbactam, the beta-lactamase inhibitor, helps inactivate the beta-lactamase enzymes produced by certain bacteria. This prevents the breakdown of cefoperazone by these enzymes, enhancing its effectiveness against resistant bacteria.
Q3.
How is Lezopure 1.5gm injection administered?
Lezopure 1.5gm injection is administered as an intramuscular injection or intravenous infusion. The duration and dosage of treatment depend on the type and severity of the infection, as well as the patient's age and weight. It is important to follow the instructions provided by the physician.
Q4.
What are the common side effects of Lezopure 1.5gm injection?
Common side effects of Lezopure 1.5gm injection may include diarrhea, nausea, vomiting, stomach pain, headache, dizziness, rash, itching, and local reactions at the injection site. Inform your healthcare provider if any side effects become severe.
Q5.
Can Lezopure 1.5gm injection be used during pregnancy or breastfeeding?
Lezopure 1.5gm injection should be used during pregnancy or breastfeeding only if needed and prescribed by a healthcare professional. It's essential to discuss the risks and benefits with your doctor before using this medication in such situations.
Fact Box of Lezopure 1.5gm Injection
Molecule name: Cefoperazone + Sulbactam | Therapeutic class: Antibiotics |
Pharmacological class: 1. Cefoperazone- Third-generation cephalosporin 2. Sulbactam- Beta-lactamase inhibitor | Indications: 1. Respiratory Tract Infections 2. Urinary Tract Infections 3. Intra-abdominal Infections 4. Septicemia 5. Meningitis 6. Skin and Soft Tissue Infections 7. Bone and Joint Infections 8. Endometritis |
References
- Pfizer Limited, [Revised on April 2020] [ Accessed on 27th June 2021], https://labeling.pfizer.com/ShowLabeling.aspx?id=14800
- Pfizer, US Food and Drug Administration, [Revised on March 2015] [ Accessed on 27th June 2021],https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/050551s043lbl.pdf
- Goodman & Gilman's, The Pharmacological Basis of Therapeutics, Penicillins, cephalosporins, and other beta-lactam antibiotics, 12th edition, 2011, 1499.
- KD Tripathi, Essentials of Medical Pharmacology, Beta-lactam antibiotics, 7th edition, 2013, 728.
Disclaimer
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Author Details
Written By
Dr. B. Deiva
Pharm D
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 31 Mar 2026 | 09:31 AM (IST)
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