Quick Summary
Lupride Depot 22.5mg Injection
Last updated on 10 Aug 2026 | 06:25 AM (IST)
₹12796
MRP: ₹15995.6
(You Save ₹3199.6)
1 VIAL(s)
Lupride Depot 22.5mg Injection is a prescription medicine used to treat hormone-sensitive conditions such as advanced prostate cancer, endometriosis, uterine fibroids, and central precocious puberty. It contains leuprolide, a gonadotropin-releasing hormone (GnRH) agonist that works by reducing the production of sex hormones like testosterone and oestrogen, helping to slow disease progression. Lupride Depot 22.5mg Injection should be administered under strict medical supervision as part of a comprehensive treatment plan.
Lupride Depot 22.5mg Injection
Salt Composition
LEUPROLIDE ACETATEMarketer
SUN PHARMACEUTICAL INDUSTRIES LTD
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MRP: ₹15,995.60
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Introduction
Lupride Depot 22.5mg injection consists of the active ingredient Leuprolide. It belongs to the class of medicines called gonadotropin-releasing hormone (GnRH) agonists. This injection treats prostate cancer in men, hormone-responsive breast cancer, endometriosis (tissue that usually lines the interior of the uterus grows outside of it), and uterine fibroids (noncancerous growths of the uterus) in women.
The Lupride Depot 22.50 mg is also used for the treatment of premature puberty, which is characterised by early physical development in children due to hormonal imbalances.
Do not receive this injection if you are allergic to Lupride Depot injection or its ingredients, including Goserelin and Triptorlin. Before receiving this medicine, inform your physician if you have a liver or kidney impairment. Inform your doctor if you have undiagnosed abnormal uterine bleeding.
Do not take this treatment if you are pregnant or planning to get pregnant. During the treatment, the existing symptoms may worsen due to the sex steroid increase in the body. Talk to your physician for more concerns. Report to your doctor if your child has a progressive brain tumour.
Before starting the treatment, notify your doctor about your underlying medical conditions, such as diabetes, seizures, heart problems with chest pain, irregular heartbeats, depression, or are at increased risk of thinning of bones (osteoporosis). This medicine is not recommended for patients with abnormal vaginal bleeding.
If you are a woman of childbearing age, use non-hormonal contraceptives while taking Lupride Depot 22.5mg injection. Report to your doctor if you are a man with urinary obstruction or had an operation to remove your testicles. Tell your doctor if you feel pressure on the spinal cord and experience urinary disorders and haematuria (blood in the urine). Lupride Depot price varies by retailer and location.
Uses
Lupride Depot 22.5mg injection uses include:
- In the treatment of Prostate cancer
- Hormone-responsive breast cancer in perimenopausal (around menopause) women
- Endometriosis (a painful illness in which the tissue that normally lines the inside of the uterus grows outside of your uterus)
- Central precocious puberty (a child’s body begins to change into an adult too soon caused by a release of certain hormones)
How Lupride Depot 22.5mg Injection Works
Lupride Depot 22.5mg decreases testosterone or estrogen production, depending on the treated condition. This helps to slow the growth of cancer cells, reduce the size of uterine fibroids, and alleviate the symptoms of endometriosis and early onset of puberty.
Interaction of Lupride Depot 22.5mg Injection with other drugs
Inform your healthcare provider about all the medicines you take, including prescription, over-the-counter, nutritional and vitamin supplements, vaccines, and herbal products. Certain medications such as Quinidine, Procainamide, Amiodarone, Sotalol, Pain killers, and Antibiotics may interact with the effects of Lupride Depot 22.5mg and reduce its effectiveness by causing undesirable side effects.
More Information about Lupride Depot 22.5mg Injection
- Keep Lupride Depot 22.5mg out of sight and reach of children.
- Store in a cool, dry place, away from direct heat and light.
- Store below 25°C
- Do not refrigerate or freeze.
How to Use Lupride Depot 22.5mg Injection
Lupride Depot 22.5mg injection is usually administered in the arm, thigh or abdomen. If this injection is recommended for you, it will be given by a healthcare professional. Do not self-administer. Your physician will choose the Lupride Depot 22.5mg injection dosage and administration frequency based on the medical condition because it differs for each person.
Safety Advice for Lupride Depot 22.5mg Injection
Breast Feeding
Lupride Depot 22.5mg injection is contraindicated in breastfeeding women. Inform your doctor if you are breastfeeding before taking this injection.
Alcohol
Consuming alcohol during the Lupride Depot 22.5mg injection treatment may increase the risk of thinning bones (osteoporosis). Hence caution should be taken. Consult your doctor for more information
Liver
Lupride Depot 22.5mg should be used cautiously in patients with liver impairment. Consult your doctor before receiving it. Notify your doctor about underlying liver conditions.
Lungs
It is unknown whether Lupride Depot 22.5mg is safe for patients with lung problems. Notify your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.
Driving
Lupride Depot 22.5mg injection can cause drowsiness, visual disturbances, or dizziness. It is unsafe; hence avoid driving if you are unwell.
Pregnancy
It is unsafe to use Lupride Depot 22.5mg injection because it is contraindicated in pregnant women. Tell your doctor if you are pregnant or planning to get pregnant before taking this treatment.
Side Effects
Lupride Depot side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Serious side effects of Lupride Depot 22.5mg Injection are:
- Severe rash, itching
- Shortness of difficulty of breath
- Cough with blood
- Pulmonary embolism
- Severe headache
Common side effects of Lupride Depot 22.5mg Injection are:
- Altered blood sugar and cholesterol levels
- Injection site reactions
- Loss of appetite
- Abnormal liver function
- Swelling in the ankle or hand
- Difficulty sleeping, headache
- Mood swings, depression
- Weight changes
- Nausea, vomiting
- Vaginal dryness, bleeding
- Loss of interest in sexual intercourse
- Hot flushes
- Bone pain, muscle weakness
- Breast tenderness
Expert tips
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During breast cancer treatment, regular checkups every three months along with an aromatase inhibitor are recommended.
-
Do not take this injection if you experience abnormal vaginal bleeding, and inform your doctor if you are still menstruating before starting treatment.
-
Report symptoms such as persistent headaches (even after painkillers), vision problems, or ringing in the ears to your doctor immediately.
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If you have diabetes, your doctor may monitor your glucose and blood sugar levels regularly during treatment.
FAQs about Lupride Depot 22.5mg Injection
Q1.
Who should not use Lupride Depot 22.5mg?
Lupride Depot 22.5mg should not be used by pregnant and breastfeeding women, people who are allergic to the medication, or people with a history of osteoporosis or bone fractures. It should also be used cautiously in people with a past of depression or mental illness.
Q2.
What should I do if I miss a dose of Lupride Depot 22.5mg?
If you miss a dose of Lupride Depot 22.5mg, contact your healthcare provider as soon as possible to schedule the missed dose. Do not double up on doses to make up for a missed one.
Q3.
Can Lupride Depot 22.5mg cause weight gain?
Weight gain is not a common side effect of Lupride Depot 22.5mg, but it may occur in some people.
Q4.
What is the use of lupride depot injection in IVF?
Lupride Depot 22.5mg injection uses include suppressing ovarian function to control the timing of ovulation during IVF treatments. It helps in improving the chances of successful fertilisation by controlling hormone levels.
Q5.
What is the cost of a lupride injection?
The MRP of a Lupride injection is Rs. 17,062. However, the actual price may vary depending on the pharmacy and location.
Fact Box
|
Molecule name: |
Leuprolide acetate |
|
Therapeutic class: |
Antineoplastics |
|
Pharmacological class: |
Gonadotropin-Releasing Hormone (GnRH) agonists |
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Indication: |
|
References
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Introduction to Endocrinology: The hypothalamic-pituitary axis, 12th edition, 2011, 1122.
- KD Tripathi, Essentials of Medical Pharmacology, Anterior pituitary hormones, 7th edition, 2013, 243.
- Takeda UK Limited, Electronic medicines compendium (emc), [ Revised on June 2022] [ Accessed on 12th April 2023], https://www.medicines.org.uk/emc/product/4651/smpc
- Abbott Laboratories, US Food and Drug Administration, [Issued on Feb 2016] [ Accessed on 12th April 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/020517s036_019732s041lbl.pdf
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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Author Details
Written By
Dr. Vijayalakshmi N.
BDS
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 10 Aug 2026 | 06:25 AM (IST)
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