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Mabura 40mg Injection PFS

Prescription Required
Cold Chain Required
adalimumab

5859

MRP: 23437.5

(You Save ₹17578.5)

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Mabura 40mg Injection PFS
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5859

MRP: 23,437.50

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Salt Composition

ADALIMUMAB

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HETERO HEALTHCARE LTD

Prepaid Only. Non-Returnable.

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Introduction

Mabura 40mg Injection PFS contains the active ingredient Adalimumab. It is an antirheumatic agent that belongs to the class of medications called TNF (tumor necrosis factor) inhibitors. It is used alone or with other medications to relieve the symptoms of certain autoimmune disorders. It is used to treat rheumatoid arthritis (a condition in which the body attacks its joints, causing pain, swelling, and loss of function), polyarticular juvenile idiopathic arthritis (a condition that affects children in which the body attacks its own joints, causing pain, swelling, loss of function, and delays in growth and development).

It is also indicated to treat enthesitis-related arthritis, ankylosing spondylitis (a condition in which the body attacks the joints of the spine and other areas, causing pain and joint damage), axial spondyloarthritis without radiographic evidence of ankylosing spondylitis, psoriatic arthritis (a condition that causes joint pain and swelling and scales on the skin), plaque psoriasis,  hidradenitis suppurativa (a skin disease that causes pimple-like bumps in the armpits, groin, and anal area), Crohn’s disease, ulcerative colitis (a condition which causes swelling and sores in the lining of the colon [large intestine] and rectum), and non-infectious uveitis (swelling and inflammation of different areas of the eye). 

Do not use Mabura 40mg Injection PFS if you are allergic to adalimumab or any of the other ingredients present in this medicine. Do not take this medicine if you have active tuberculosis or other severe infections. Do not consume this medicine if you have moderate or severe heart failure. Inform your physician if you have any active infection before starting the treatment. Tell your doctor if you have lung problems, heart diseases, liver or kidney disorders before initiating the treatment. If you are pregnant, think you may be pregnant, or are planning to have a baby, ask your doctor for advice about taking this medicine. Mabura 40mg injection cost varies by retailer and location.

 

Uses

  • Rheumatoid arthritis

  • Polyarticular juvenile idiopathic arthritis

  • Enthesitis-related arthritis

  • Ankylosing spondylitis

  • Axial spondyloarthritis without radiographic evidence of ankylosing spondylitis

  • Psoriatic arthritis

  • Plaque psoriasis

  • Hidradenitis suppurativa

  • Crohn’s disease

  • Ulcerative colitis

  • Non-infectious uveitis

How Mabura 40mg Injection PFS Works

The active ingredient in this medicine is a human monoclonal antibody. Monoclonal antibodies are proteins that attach to a specific target. The target of Mabura 40mg Injection PFS is a protein called tumor necrosis factor (TNFα), which is involved in the immune (defense) system and at increased levels in the inflammatory diseases.  By attaching to TNFα, Humira decreases inflammation in these diseases.

Interaction of Mabura 40mg Injection PFS with other drugs

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, vaccines, nutritional and vitamin supplements, and herbal products. Certain medications interact with Mabura 40mg Injection PFS and reduce its effectiveness by causing undesirable side effects.

Storage Conditions

  • Store in a refrigerator (2°C – 8°C).

  • Do not freeze.

  • Protect the medicine from light and excessive moisture.

  • Keep the medicine out of reach of children and pets

How to consume Mabura 40mg Injection PFS

Your doctor will decide the dose, duration, and frequency of administration based on your disease condition, severity and other factors. Always use this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure.  

This medicine is to be administered by injection under the skin (subcutaneously). Your doctor or other healthcare professional will train you on how to use this injection. Do not self-administer this injection until you get trained. Your doctor will decide the dose, duration, and frequency of administration based on your disease condition, severeity and other factors.

Safety Advices

Pregnancy-Consult Your Doctor

Pregnancy

Consult Your Doctor

Do not take Mabura 40mg Injection PFS during pregnancy unless your doctor says. Inform your physician if you are pregnant, suspecting, or planning to get pregnant during the treatment. Use effective contraception during the treatment and for at least 5 months after the last dose.  

Breast Feeding-Consult Your Doctor

Breast Feeding

Consult Your Doctor

Mabura 40mg Injection PFS can be used during breastfeeding. However, inform your physician if you are breastfeeding

Lungs-Consult Your Doctor

Lungs

Consult Your Doctor

Mabura 40mg Injection PFS should be taken cautiously in patients with lung problems. Inform your physician if you have any lung diseases before initiating the treatment.   

Liver-Consult Your Doctor

Liver

Consult Your Doctor

Mabura 40mg Injection PFS should be taken cautiously in patients with liver problems. Inform your physician if you have any liver diseases before initiating the treatment.  

Alcohol-Consult Your Doctor

Alcohol

Consult Your Doctor

It is unknown whether consuming alcohol is safe during the treatment with Mabura 40mg Injection PFS. Consult your doctor for more advice.  

Driving-Unsafe

Driving

Unsafe

Mabura 40mg Injection PFS may have a small effect on your ability to drive, cycle or use machines. Room spinning sensation and vision disturbances may occur after taking this medicine.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

Common

  • Injection site reactions

  • Rash

  • Headache

  • Sinusitis

  • Upper respiratory infections

  • Fever

Serious 

  • Heart problems

  • Abnormal heart beat

  • Severe skin reactions

  • GI bleeding

  • Abnormal blood count values

  • Liver injury

  • Bone problems

  • Infections

  • Severe respiratory problems

Expert tips

  1. Vaccine caution: Avoid taking live vaccines while on this medicine, as certain vaccines can cause infections — always check with your doctor before vaccination.

  2. Hepatitis B risk: Inform your doctor if you have or previously had hepatitis B, as this medicine may reactivate the infection.

  3. Self-injection guidance: If instructed to inject at home, ensure you fully understand the proper technique and dosage instructions.

  4. Injection site rotation: Use different body areas for each injection, avoiding red, bruised, or tender skin, and keep track of injection sites.

  5. Missed dose instructions: Take a missed dose as soon as you remember, but skip it if it’s almost time for the next one, never double the dose

FAQs

Q1.

How long does it take for Mabura 40mg Injection PFS to start working?

The response to Mabura 40mg Injection PFS can vary among individuals and the condition being treated. Some individuals may experience improvement in symptoms within a few weeks, while others may take longer. It is important to follow the healthcare provider's instructions and allow sufficient time for the medication to take effect.

Q2.

Can Mabura 40mg Injection PFS increase the risk of infections?

Mabura 40mg Injection PFS may increase the risk of serious bacterial, viral, or fungal infections. It is essential to promptly report any signs of infection to a healthcare provider while taking this medicine. Inform your physician if you have or had any active infections.

Q3.

 What are the common side effects of Mabura 40mg Injection PFS?

Common side effects of Mabura 40mg Injection PFS may include injection site reactions, such as pain, redness, or swelling. Other possible side effects include headaches, upper respiratory infections, nausea, and rash. Serious side effects are rare but can occur.

Q4.

How long can I take Mabura 40mg Injection PFS?

The duration of Mabura 40mg Injection PFS treatment can vary depending on the individual's condition and response to the medication. In some cases, this medicine may be used as a long-term maintenance therapy, while treatment duration may be shorter in other situations. It is important to follow the healthcare provider's guidance regarding the appropriate duration of treatment.

Q5.

 Can Mabura 40mg Injection PFS be used in individuals with kidney or liver impairment?

Mabura 40mg Injection PFS may require dosage adjustments or caution in individuals with kidney or liver impairment. Healthcare providers will assess the patient's situation and determine the appropriate dosage based on renal and hepatic function

Fact Box

Molecule name: 

Adalimumab

Therapeutic class:

  Antirheumatic agent, Monoclonal antibody

Pharmacological class:

TNF inhibitors

    Indications: 

  1.  Rheumatoid arthritis 

   2. Polyarticular juvenile idiopathic arthritis 

   3. Enthesitis-related arthritis 

   4. Ankylosing spondylitis

   5. Axial spondyloarthritis without radiographic                                                                                                       e    evidence of ankylosing spondylitis

   6. Psoriatic arthritis

   7. Plaque psoriasis

   8. Hidradenitis suppurativa

   9. Crohn’s disease

   10. Ulcerative colitis

   11. Non-infectious uveitis

 

References

  1. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Immunosuppressants, Tolerogens, and Immunostimulants, 12th edition, 2011, 1018.

  2. KD Tripathi, Essentials of Medical Pharmacology, Antirheumatoid and antigout drugs, 7th edition, 2013, 213.

  3. AbbVie Ltd, Electronic medicines compendium (emc), [ Revised on April 2021] [ Accessed on July 2023], https://www.medicines.org.uk/emc/files/pil.2150.pdf

  4. AbbVie Inc, US Food and Drug Administration, [ Revised on Feb 2021] [ Accessed on July 2023], https://www.rxabbvie.com/pdf/humira.pdf

Disclaimer

MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.

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