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Maintane 500mg Injection
Prescription Required
Salt Composition : Hydroxyprogesterone
Manufacturer : JAGSONPAL PHARMACEUTICALS LIMITED
Origin of Medicine : India
1 Vial(s)
Introduction to Maintane 500mg Injection
Maintane 500mg Injection contains the active constituent Hydroxyprogesterone, a synthetic progestin classified under hormonal therapies. It is mainly used to help reduce the risk of preterm birth in women with a history of spontaneous preterm delivery. This hormone works by supporting the uterine environment and promoting pregnancy maintenance.
Maintane 500mg Injection is usually administered as an intramuscular injection and is considered a supportive therapy under strict medical supervision. It is contraindicated in women with hormone-sensitive cancers, active liver disease, or unexplained vaginal bleeding. Patients should inform their doctor about any history of clotting disorders or allergies. Caution is advised in those with hypertension, diabetes, or epilepsy. Always use this medication under medical guidance to ensure both maternal and fetal safety. The Maintane 500 injection price typically ranges in India, depending on the pharmacy and location.
Uses of Maintane 500mg Injection
- Prevention of recurrent preterm birth in women with a singleton pregnancy and a history of spontaneous preterm delivery
- Adjunct in treating amenorrhea (as per specific protocols)
- Management of selected gynecological hormone imbalances (off-label)
Therapeutic Effects of Maintane 500mg Injection
Maintane 500mg Injection helps maintain pregnancy by mimicking the action of the natural hormone progesterone. It stabilizes the lining of the uterus and prevents early contractions that may lead to preterm birth. Unlike some hormonal treatments, it does not stimulate the uterus but works gently to support fetal development. This makes it a preventive therapy for women with a history of early labor, helping to reduce the chances of recurrence.
Interaction of Maintane 500mg Injection with other drugs
Serious drug interactions may occur when Maintane 500mg Injection is combined with other hormone therapies, anticoagulants, or medications that affect liver enzymes.
Avoid concurrent use with:
- Estrogen-containing therapies: May increase the risk of thromboembolic events
- Rifampin or other enzyme inducers: May reduce the effectiveness of Hydroxyprogesterone
- Corticosteroids or immunosuppressants: May enhance side effects like fluid retention
- Anticoagulants (e.g., warfarin): Increased risk of bleeding or clotting irregularities
Contraindications include:
- Known or suspected breast or genital cancers
- History of thrombophlebitis or thromboembolic disorders
- Liver tumors or active liver disease
- Undiagnosed vaginal bleeding
- Known hypersensitivity to the drug or its components
More Information about Maintane 500mg Injection
- Storage: Store between 2°C to 8°C. Do not freeze.
- Missed Dose: Contact your doctor immediately. Do not double dose.
- Overdose: Seek medical help. Symptoms may include nausea, dizziness, or fluid retention.
- Additional Tip: Always take your dose on the same day each week as scheduled.
How to consume Maintane 500mg Injection
Maintane 500mg Injection is given as a 250 mg intramuscular injection, usually once weekly. It is administered by a healthcare professional into the upper outer quadrant of the gluteal muscle. It should not be self-injected. Food does not affect the action of this drug.
Safety Advices for Maintane 500mg Injection
Pregnancy
Used specifically in pregnancy to prevent preterm birth
Breast Feeding
Limited data available; weigh benefits and risks
Lungs
Avoid if you have active liver disease
Liver
Caution in severe respiratory disorders
Alcohol
May interfere with hormonal balance
Driving
Does not impair alertness or coordination
Side Effects of Maintane 500mg Injection
Common Side Effects
- Injection site pain or swelling
- Headache
- Nausea
- Fatigue
- Mild fluid retention
Serious Side Effects
- Signs of blood clots (leg pain, chest pain, difficulty breathing)
- Jaundice or liver dysfunction
- Severe allergic reaction (rash, itching, swelling)
- Vision changes or severe headache
Word of Advice
Maintane 500mg Injection should be used under regular medical supervision. Always attend scheduled visits for monitoring and injection. Do not stop the treatment without consulting your doctor, even if you feel fine. Avoid using any hormonal products, herbal remedies, or supplements without prior approval. Inform any new doctor about your ongoing therapy, especially before surgeries or new prescriptions. Keep a record of doses taken for your and your doctor’s reference.
FAQs
Q 1. What is Maintane 500mg Injection used for?
It is mainly used to prevent preterm birth in pregnant women who have previously delivered early.
Q 2. When should I start taking Maintane 500mg Injection during pregnancy?
Typically between 16 and 20 weeks of pregnancy, continuing up to 36 weeks, as advised by your doctor.
Q 3. Is Maintane 500mg Injection safe during breastfeeding?
Consult your doctor. There is limited data, and decisions are made case by case.
Q 4. Can Maintane 500mg Injection cause weight gain?
Mild fluid retention and bloating may occur, but significant weight gain is uncommon.
Q 5. What happens if I miss a dose?
Contact your doctor immediately. A missed injection can reduce the effectiveness of treatment.
Q 6. What is the injection maintane 500 price in India?
The inj maintane 500mg price in India typically ranges based on the location.
Fact Box of Maintane 500mg Injection
| Molecule Name: Hydroxyprogesterone | Therapeutic Classification: Hormonal Therapy |
| Pharmacological Classification: Synthetic Progestin | Indications: Prevention of preterm birth in high-risk pregnancies |
References
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/021945s005lbl.pdf
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/021945s012lbl.pdf
- https://www.ema.europa.eu/en/medicines/human/referrals/hydroxyprogesterone-caproate-containing-medicinal-products
- https://pubchem.ncbi.nlm.nih.gov/compound/Hydroxyprogesterone#section=3D-Conformer
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
