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Mecobion NP Tablet_202384
Mecobion NP Tablet_202384
15% Off

Mecobion NP Tablet

Prescription Required

Salt Composition : Nortriptyline,pregabalin,methylcobalamin


Origin of Medicine : India

MRP: 230
Price :196
You Save :34 (15%)

10 Tablet(s) In A Strip

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Introduction to Mecobion Np Tablet

Mecobion NP tablet contains an active component as Nortriptyline, pregabalin, and methylcobalamin. Nortriptyline is an antidepressant medication that belongs to the class of drugs known as tricyclic antidepressants (TCAs). Pregabalin is an anticonvulsant and antiepileptic medication used to treat neuropathic pain, especially in conditions like diabetic neuropathy, postherpetic neuralgia, and fibromyalgia. Methylcobalamin is a form of vitamin B12, an essential nutrient for the body. It is used as a dietary supplement to treat vitamin B12 deficiency, which can lead to anemia and nervous system problems. 

Individuals with known hypersensitivity or allergy to Mecobion NP tablets or other components of these medications should not take them. It is primarily eliminated through the kidneys. Therefore, individuals with severe renal impairment or end-stage renal disease should not use this medication. There is limited data on the safety of Mecobion NP tablet during pregnancy and breastfeeding. Pregnant or breastfeeding individuals should consult their healthcare provider before using this medication.

Uses of Mecobion Np Tablet

Mecobion NP tablet is used to treat the following:

  • Neuropathic pain

Therapeutic Effects of Mecobion Np Tablet

Healthcare professionals prescribe these medications in specific cases where the patient's medical condition requires multimodal treatment. For example, some individuals with neuropathic pain may benefit from a combination of nortriptyline and pregabalin as they work through different mechanisms to address pain and may have a synergistic effect. Nortriptyline works by affecting the levels of certain neurotransmitters in the brain, such as serotonin and norepinephrine, which play a role in regulating mood and pain perception. Pregabalin works by reducing the release of certain neurotransmitters in the brain, which helps to decrease pain signals and alleviate anxiety symptoms. Methylcobalamin can be added to support nerve health and potentially enhance the treatment outcomes.

Interaction of Mecobion Np Tablet with other drugs

Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with the Mecobion NP tablet, reducing effectiveness by causing undesirable side effects. 

More Information about Mecobion Np Tablet

  • Store at room temperature, between 20°C to 25°C (68°F to 77°F).
  • Keep away from moisture, heat, and light.
  • It should not be frozen.
  • Keep away from children and pets.

How to consume Mecobion Np Tablet

Mecobion NP tablet can be administered orally in tablet form. The specific usage instructions may vary depending on the condition being treated, age, and the individual's weight. Oral tablets are typically taken with water, as directed by the healthcare provider. 

Safety Advices for Mecobion Np Tablet

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The safety of Mecobion NP tablet during pregnancy has not been extensively studied, and limited information is available regarding its use in pregnant women. So it is advisable to consult a healthcare provider before using it.

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Breast Feeding


The safety of Mecobion NP tablet during breastfeeding has not been well studied, and limited information is available regarding its excretion into breast milk. As a result, it is recommended to exercise caution when using it while breastfeeding.

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Individuals with pre-existing lung conditions must inform their healthcare provider about their medical history before starting any new medication.

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If you have a liver impairment or concerns about the safety of using Mecobion NP tablet, discuss these with your healthcare provider. They can provide personalized guidance and ensure the most appropriate treatment plan for your medical condition.

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Mecobion NP tablet with alcohol can increase the risk of certain side effects and adverse reactions. It is generally recommended to avoid or limit alcohol consumption while taking these medications.

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Mecobion NP tablet can cause side effects that may impair driving abilities in some individuals. Therefore, caution is advised when operating a vehicle or performing any tasks that require alertness and concentration while taking these medications.

Side Effects of Mecobion Np Tablet

Mecobion NP tablets cause some side effects like all medications, although not everyone will experience them. 

Serious side effects:

  • Allergic reactions (e.g., rash, hives, difficulty breathing)
  • Swelling of the hands, feet, or ankles
  • Unusual bleeding or bruising
  • Mood changes or depression
  • Suicidal thoughts
  • Irregular heartbeat
  • Severe dizziness or fainting

Common side effects:

  • Constipation
  • Dry mouth
  • Headache
  • Feeling sleepy, tired or dizzy
  • Diarrhoea
  • Weight gain
  • Blurred vision


Word of Advice

If you have prescribed Mecobion NP tablet for neuropathic pain, follow your healthcare provider's instructions carefully. Monitor for unusual symptoms, such as mood changes and irregular heartbeat. If you experience any unusual or severe side effects while taking these medications, contact your doctor immediately. Pregnant or breastfeeding individuals should inform their obstetrician or healthcare provider before using this combination, as certain medications may not be safe during pregnancy or lactation. Regularly attend follow-up appointments and communicate openly with your healthcare provider about any concerns or questions for a successful and safe diabetes management journey. 


Q 1. What is the purpose of the combination of nortriptyline, pregabalin, and methylcobalamin?

This combination may be prescribed for individuals with certain medical conditions that require multimodal treatment. Nortriptyline is an antidepressant that may help with depression and neuropathic pain, while pregabalin is used to treat neuropathic pain and certain anxiety disorders. Methylcobalamin is a form of vitamin B12 that supports nerve health. The combination aims to address pain and neurological symptoms effectively.

Q 2. Are there any specific precautions or side effects associated with Mecobion NP tablet?

Yes, there may be specific precautions and side effects associated with Mecobion NP tablet. Patients should consult their healthcare provider before starting this treatment to discuss individual health concerns, potential drug interactions, and any contraindications.

Q 3. Can I take this combination if I am pregnant or breastfeeding?

Pregnant or breastfeeding individuals should consult their healthcare provider before taking this medication. Some medications may be unsafe during pregnancy or breastfeeding, and alternative treatments may be considered.

Q 4. How should I take Mecobion NP tablet?

Follow your doctor's instructions carefully regarding dosage, timing, and any specific recommendations for taking Mecobion NP tablet. Never alter the prescribed dosages without consulting your healthcare provider.

Q 5. Is Mecobion NP tablet addictive?

Mecobion NP tablet has the potential for abuse and dependence, especially in individuals with a history of substance abuse.

Fact Box of Mecobion Np Tablet

Molecule name: Nortriptyline, Pregabalin, Methylcobalamin

Therapeutic class: Antidepressant and Anticonvulsive

Pharmacological class: 

  1. Nortriptyline: Tricyclic antidepressants
  2. Pregabalin: Anticonvulsant
  3. Methylcobalamin: Vitamin B12 Supplement
Indications: Neuropathic pain


  1. Ram Prabhoo et al., Efficacy and Tolerability of a Fixed Dose Combination of Methylcobalamin and Pregabalin in the Management of Painful Neuropathy, [Revised on 4/11/2012] [Accessed on 19/07/2023],
  2. Yasmin U Dongre et al., Sustained-release pregabalin with methylcobalamin in neuropathic pain: an Indian real-life experience [Revised on 19/5/2013] [Accessed on 19/07/2023],


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