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Mega Ace 80mg Tablet
Last updated on 06 Jul 2026 | 07:25 AM (IST)
₹475
MRP: ₹557.81
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Introduction
Mega Ace 80mg tablet contains Megestrol. It belongs to a category of medications called progestogens and is used to treat certain hormone-dependent cancers, namely breast cancer. It is a synthetic form of the naturally occurring progesterone hormone. It is also indicated to treat unexplained weight loss, cachexia (weakness) and anorexia (loss of appetite) in patients with weak immune systems and cancer.
Progestogens are used in patients whose disease has progressed with conventional anti-estrogen therapy. Your physician will assess the estrogen status (ER) to ensure that your breast cancer is due to the expression of the estrogen receptor.
Uses of Mega Ace 80mg Tablet
- Treatment of hormone-dependent cancer (endometrial cancer, breast cancer)
- Treatment of anorexia, cachexia or unexplained weight loss
How Mega Ace 80mg Tablet Works
Mega Ace 80 tablet exhibits anticancer properties by interacting with steroidal receptors. It suppresses steroid production by the adrenal glands and androgen secretion by the ovaries in postmenopausal women. It also prevents the breakdown of cytokines and stimulates appetite in chronic disease-induced anorexia and cachexia.
Interaction of Mega Ace 80mg Tablet with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications interact with Mega ace 80mg tablet and reduce its effectiveness by causing undesirable side effects.
Storage Conditions
- Store below 25°C.
- Protect from light and moisture.
- Keep away from children and pets
How to take Mega Ace 80mg Tablet
Swallow the tablet whole with water. Mega Ace 80mg Tablet Dosage will be decided by your physician depending on your condition. Do not crush or chew the tablet.
Safety Advice for Mega Ace 80mg Tablet
Breast Feeding
Consult your physician before taking this tablet if you are a breastfeeding mother.
Alcohol
It is recommended to avoid alcohol during the treatment with this medication as it reduces effectiveness of medication and enhances changes of side effects.
Liver
Inform your physician before starting this treatment if you have liver problems. Your physician will monitor your liver functions regularly.
Lungs
Inform your physician before starting this treatment if you have lung diseases.
Driving
Avoid driving or using machinery if you experience side effects.
Pregnancy
This medicine is unsafe to consume during pregnancy. Inform your physician before starting this treatment if you are pregnant or think you might be pregnant.
Side Effects of Mega Ace 80mg Tablet
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
- Swelling of the face, lips, tongue
- Skin rash
- Breathing difficulty
- Blood clot in the lungs
- Heart problems
Common
- Weight gain and increased appetite
- Hot flushes
- High BP
- High blood sugar levels
- Rounded face
- Constipation
- Swelling of vein
- Mood changes
- Hair loss
- Diarrhea
- Tiredness and weakness
- Impotence
- Passing wind
- Frequent urination
- Nausea, vomiting
- Fluid accumulation
- Pain
Expert Tips
- Inform the doctor if the patient has any history of kidney, liver, or allergic reactions before starting this medication.
- Kidneys, liver, blood pressure and blood glucose levels should be monitored while taking this medication and avoid taking this medication while planning for pregnancy or during pregnancy, as it causes harmful effects on developing babies.
- This medication should not be stopped without proper advice from the doctor because it can worsen the situation.
- Inform the doctor immediately if there are any signs of swelling and pain in the limbs, shortness of breath, chest pain, severe headache, or changes in vision.
FAQs about Mega Ace 80mg Tablet
Q1.
Does Mega ace 80mg tablet cause weight gain?
Yes, it is a common side effect which is caused due to an increase in appetite. It leads to an increase in fat and body mass. If there is excessive weight gain patients are advised to consult the doctor.
Q2.
Is Mega ace 80mg tablet safe to use during pregnancy?
No, it is unsafe to use this medication in pregnancy because it causes harmful effects in the developing baby. Patients are asked to avoid this medication if they are planning for pregnancy or during pregnancy.
Q3.
Does Mega ace 80mg tablet stop periods?
No, it doesn't stop periods and it can cause excessive bleeding. consult the doctor if there is any excessive bleeding.
Q4.
What are the side effects of Mega ace 80mg tablet?
The common side effects of Mega ace 80mg tablet are weight gain, increase in appetite, high blood pressure, constipation, rounded face, mood changes, hair loss, tiredness and weakness, nausea, vomiting, swelling of the vein.
Q5.
Can I drive after taking Mega ace 80mg tablet?
It is unsafe to use this medication while driving as it causes dizziness and patients may lack concentration and alertness.
Fact Box of Mega Ace 80mg Tablet
| Molecule: Megestrol | Therapeutic class: Hormones and Hormone Antagonists |
| Pharmacological class: Progestin | Indications: 1. Hormone-dependent cancer (endometrial cancer, breast cancer) 2. Cachexia |
References
- Bausch and Lomb UK Ltd., Electronic Medicines Compendium (EMC), [Revised on Sep 2020] [Accessed on 17th Jul 2021], https://www.medicines.org.uk/emc/files/pil.11135.pdf
- Alniche Life Sciences Pvt Ltd., [Revised on 2021] [Accessed on 19th Jul 2021], https://www.alniche.com/product/megahenz/
- Bines et al., Activity of Megestrol acetate in postmenopausal women with advanced breast cancer after nonsteroidal aromatase inhibitor failure: a phase II trial, Annals of Oncology, 2014, 25(4), 831-836, https://www.annalsofoncology.org/action/showPdf?pii=S0923-7534%2819%2936501-9
- G.G. Dark, A.R. Abdul Razak, Oncology, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 259-282.
Disclaimer
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Author Details
Written By
Dr. Archana Gupta
BDS
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 06 Jul 2026 | 07:25 AM (IST)
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