Mexate 5mg Tablet 10's contains the active substance Methotrexate. It is an anti-metabolite and immunosuppressant drug. It treats certain types of cancer, such as acute lymphocytic leukaemia (ALL), meningeal leukaemia, non-hodgkin lymphoma, osteosarcoma, cutaneous T-cell lymphoma, breast cancer, and head and neck cancer in adults. It is also used to treat severe psoriasis in adults (a skin disease in which red, scaly patches form on some body areas). It is also indicated for the treatment of rheumatoid arthritis in adults. 

Do not use Mexate 5mg Tablet 10's  if you are allergic to methotrexate or any of the other ingredients of this medicine. Do not take this medicine if you have kidney or liver problems, blood disorders, weakened immune system, are pregnant, or breastfeeding. Inform your physician immediately if you experience any symptoms of spitting and coughing up blood, general muscle weakness, vision disturbance, changes in thinking, memory, and orientation problems. This medicine may impair fertility. Avoid getting pregnant during the treatment and for six months after the last dose. 

Tell your doctor if you have a stomach ulcer, active infection, or mild kidney problems and about any recent vaccinations before starting the treatment. Mexate 5mg Tablet 10's can cause serious side effects even with low doses; hence, regular follow-ups and routine laboratory tests will be necessary as a precaution. Do not use this medicine if you are pregnant, breastfeeding, or planning to get pregnant.

• To treat certain types of cancers

• To treat severe psoriasis

• To treat rheumatoid arthritis

Mexate 5mg Tablet 10's inhibits dihydrofolic acid reductase. Therefore, this medicine interferes with DNA synthesis, repair, and cellular replication. Actively proliferating tissues such as malignant cells, bone marrow, fetal cells, buccal and intestinal mucosa, and urinary bladder cells are, in general, more sensitive to this medicine. Blocking these slows down how fast cancer cells grow, spread, and suppress the immune system in autoimmune diseases.

Inform your healthcare provider about all the medicines you take, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications interact with Mexate 5mg Tablet 10's and reduce their effectiveness by causing undesirable side effects.

• Store the Mexate 5mg Tablet 10's below 25°C

• Do not freeze

• Protect the medicine from light and excessive moisture.

• Keep the medicine out of reach of children and pets

• If you forgot to take the injection, inform your healthcare professional immediately and reschedule the appointment.

Always use this medicine as exactly prescribed by your doctor. Depending on the condition being treated, your physician decides the dose, dosage, and frequency of this injection. Mexate 5mg Tablet 10's is injected into a vein (intravenously) or into muscle (intramuscularly). Do not self-administer this medicine. 

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

Common

• Hair loss

• Photosensitivity

• Rash

• Diarrhea, Nausea and Vomiting

• Decreased WBC and platelet count

• Dizziness

• Tiredness, fever, and shivering

• Blurred vision

Serious 

• Severe allergic reactions

• Spitting or coughing blood

• Chest pain

• Weakness on one side of the body

• Muscle weakness

1. Avoid alcohol and vaccines during treatment, as they may increase the risk of side effects like liver damage or reduced effectiveness.

2. Use sunscreen and protective clothing, as this medicine can make your skin more sensitive to sunlight.

3. It may affect fertility, so consult your doctor if you’re planning for a baby or are concerned about reproductive health.

4. Men with female partners who could become pregnant should use birth control during treatment and for 3 months after the last dose.

5. This medicine may increase the risk of bleeding or infections, so take extra care to avoid injury and keep hands clean to prevent illness.