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Mycomune S 360mg Tablet
Last updated on 29 Apr 2026 | 06:17 AM (IST)
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MRP: ₹1123
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Mycomune S 360 mg Tablet is a prescription immunosuppressant medicine used to prevent organ rejection in patients who have undergone kidney, heart, or liver transplantation. It contains mycophenolate sodium, which works by suppressing the activity of immune cells that can attack the transplanted organ. Mycomune S is taken under strict medical supervision as part of a long-term post-transplant treatment plan.
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Introduction
Mycomune S 360mg tablet is an immunosuppressant with an active ingredient called Mycophenolate sodium. It belongs to the inosine monophosphate dehydrogenase (IMPDH) inhibitor category. This medicine is used to prevent organ rejection in individuals who have previously received an organ transplant (such as kidney, heart, or liver transplantation). It is prescribed as part of a combination therapy that includes other immunosuppressive drugs.
This drug is contraindicated during pregnancy due to the risk of birth defects and miscarriage. It should not be advised in pregnant women unless there are no relevant alternatives and the potential benefits outweigh the risks. Female patients with reproductive potential are highly advised to use effective contraception while taking this tablet to prevent pregnancy. Live vaccines should not be administered while a person is taking Mycomune S 360mg tablet due to reduced vaccine effectiveness and the risk of infection. Individuals taking this drug should not donate blood during treatment and at least six weeks after stopping treatment. It ensures that the medication has been adequately cleared from the body before donating blood.
It is generally advised not to take this medicine if you are allergic to the drug or any other ingredients. Inform your doctor if you have liver or heart disease before initiating the treatment. As this drug reduces the body's immune defenses, it can increase the chance of skin cancer. Individuals must take precautions to limit their exposure to sunlight and ultraviolet (UV) light. Seek your doctor immediately if you develop any bruising under the skin, fever, unexplained tiredness, dizziness, yellowing of the skin or eyes, vision impairment, reduced urine output, and seizures after taking this medicine. Mycomune S 360mg tablet is an immunosuppressive medication. It may affect the infant's developing immune system and should be avoided in breastfeeding.
Uses
Prevent organ transplant rejections.
How Mycomune S 360mg Tablet Works
Mycomune S 360mg tablet works by inhibiting the enzyme inosine monophosphate dehydrogenase (IMPDH) and reducing the production of guanosine nucleotides. MMF specifically affects the proliferation of activated T and B lymphocytes. These lymphocytes are key players in the immune response that can lead to the rejection of a transplanted organ.
Interaction of Mycomune S 360mg Tablet with other drugs
Taking Mycomune S 360mg Tablet (mycophenolate sodium) with any of the following medicines can change the effect of either of them and may increase the risk of side effects.
Live vaccines such as Measles, Mumps, Rubella, or BCG (Injection Route) Life-threatening
Do not receive during treatment.
This medicine suppresses the immune system and may increase the risk of serious infections after vaccination.
Azathioprine or other strong immunosuppressants (Oral/Injection Route) Life-threatening
Use only under strict medical supervision.
Concomitant use may greatly increase the risk of severe infections and bone marrow suppression.
Antacids containing Magnesium or Aluminium (Oral Route) Moderate
Do not take at the same time.
These medicines may reduce the absorption of mycophenolate and decrease its effectiveness.
Cholestyramine (Oral Route) Moderate
Avoid using together unless advised.
It may lower mycophenolate levels and reduce its effect.
Acyclovir or Ganciclovir (Oral/Injection Route) Moderate
Use with caution.
Concomitant use may increase the levels of these medicines and raise the risk of kidney problems or blood disorders.
Oral contraceptive pills (Oral Route) Moderate
Use additional contraception.
Mycophenolate may reduce the effectiveness of hormonal contraceptives.
Warfarin (Oral Route) Mild
Use with caution.
Monitoring may be required as changes in clotting response can occur.
Storage Conditions
Store Mycomune S 360mg tablet at room temperature between (15°C to 30°C)
Keep the medicine away from the reach of children and pets.
How to consume Mycomune S 360mg Tablet
It is an orally available prescription drug. Your physician will decide the dose and duration of the treatment based on your disease condition, severity, and other factors. Always take Mycomune S 360mg tablet as prescribed by your doctor. Do not open, crush, break, or chew the medicine. Take the medicine at the same time every day as advised by your doctor.
Safety Advice for Mycomune S 360mg Tablet
Breast Feeding
Mycomune S 360mg tablet is not recommended for breastfeeding mothers because small amounts of the drug can pass into the mother's milk and affect the nursing baby.
Alcohol
It is unsafe to consume alcohol when taking Mycomune S 360mg tablet because it may cause excessive drowsiness or liver problems.
Liver
Mycomune S 360mg tablet should be cautiously administered in patients with lung diseases. Dose adjustments are necessary. Inform your physician if you have lung problems before initiating the therapy.
Lungs
It is generally considered safe for individuals with liver disease; however, inform your physician if you have any liver diseases.
Driving
Driving vehicles or operating machinery while taking Mycomune S 360mg tablet is unsafe because it may cause drowsiness and vision problems.
Pregnancy
Mycomune S 360mg tablet is known to have harmful effects on the developing fetus and is generally not taken during pregnancy unless your doctor prescribes the medicine.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
Infections, fever, or sore throat
Unusual bleeding or bruising
Low blood cell count
Severe allergic reactions
Common
Higher risk of developing lymphoma and other cancers
Nausea, abdominal pain
Diarrhea
Constipation
Loss of appetite
Shortness of breath
Weight loss
Increased heartbeat
Headache
Blood pressure problem
Anaemia
Expert Tips
Take the medicine exactly as prescribed by your doctor.
Inform your doctor about all medicines you are taking, including prescription, over the counter, and herbal products, as interactions may occur.
If you are planning to conceive or suspect pregnancy during treatment, consult your doctor immediately.
Your doctor may adjust your treatment or suggest safer alternatives if needed.
FAQs
Q1.
Can I breastfeed while taking Mycomune S 360mg tablet?
Breastfeeding is generally not recommended while taking Mycomune S 360mg tablet. This drug can pass into the mother's breast milk and may hurt the nursing infant. Consult your doctor about breastfeeding if you are taking this tablet.
Q2.
How does Mycomune S 360mg tablet work?
Mycomune S 360mg tablet suppresses the immune system, preventing it from attacking the transplanted organ. It inhibits the activity of certain immune cells involved in the rejection process.
Q3.
What will happen if I stop taking Mycomune S 360mg tablet suddenly?
Stopping your treatment all of a sudden may cause your condition to become worse. Do not stop taking Mycomune S 360mg tablet without consulting your doctor.
Q4.
How should I take Mycomune S 360mg tablet?
Follow the instructions advised by your doctor or the medication label. Mycomune S 360mg tablet is taken orally with food to improve absorption. It should be swallowed, not chewed or broken.
Q5.
Can I drink alcohol while taking Mycomune S 360mg tablet?
It is highly recommended to limit or avoid alcohol consumption while taking Mycomune S 360mg tablet. Alcohol can interact with the medication, increasing the risk of side effects or interfering with its effectiveness.
Q6.
Whether Mycomune S 360mg tablet can cause miscarriage?
Yes, Mycomune S 360mg tablet can cause miscarriage. If you have childbearing potential, use effective contraception before or during treatment and at least six weeks after discontinuing the medication. Discuss contraceptive options with your doctor properly.
Q7.
Can I get vaccinated during the treatment with Mycomune S 360mg tablet?
Live vaccines should be avoided while taking Mycomune S 360mg tablet due to the risk of infection. Inform your healthcare provider about your immunization history and consult them regarding the appropriate timing of vaccinations.
Fact Box
Molecule name: Mycophenolate sodium | Therapeutic class: Immunosuppressants |
Pharmacological class: Inosine monophosphate dehydrogenase (IMPDH) inhibitor | Indications: Prevent organ transplant rejections |
References
- Novartis Ireland Limited, European Medicine Consortium (EMC), [Revised on Nov 2022], [Accessed on 25/05/2023], https://www.medicines.org.uk/emc/files/pil.5560.pdf
- S.E. Marshall, Immunological Factors in Disease, Davidson's Principles and Practice of Medicine, 22nd Edition, 2014, 71-96.
- KD Tripathi, Immunosuppressant Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019,.937-945.
- Goodman & Gilman's, The Pharmacological Basis of Therapeutics, Inflammation, Immunomodulation, and Hematopoiesis, 12th Edition, 2011, 1014.
Disclaimer
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Author Details
Written By
P. Thirumal Reddy
B. Pharm
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 29 Apr 2026 | 06:17 AM (IST)
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