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Myelostem 50mg Injection
Last updated on 31 Mar 2026 | 09:30 AM (IST)
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Introduction to Myelostem 50mg Injection
Myelostem 50mg injection contains the active constituent melphalan. It is an anticancer agent that belongs to the class of medications called alkylating agents. It is used to treat multiple myeloma (a type of cancer of the bone marrow). It is also used to treat advanced breast and ovarian cancer. It is also indicated to treat polycythemia vera (a disease that increases the number of red cells in your blood. This makes the blood thicken and causes blood clots). It works by reducing the number of abnormal cells your body makes.
Do not take this injection if you are allergic to myelostem 50mg injection or any of the other ingredients. Inform your physician if you have had radiotherapy or cancer chemotherapy recently or have a kidney problem. Do not take this medicine if you are pregnant or planning for pregnancy. Inform your doctor if you have been vaccinated recently or planning to take any vaccination. Report to your physician immediately if you have a rash, lumps or hives on the skin, swollen face, eyelids, or lips, sudden wheezing, and chest tightness after consuming the medicine.
Uses of Myelostem 50mg Injection
- Multiple myeloma
- Advanced breast cancer
- Advanced ovarian cancer
- Polycythemia vera
Therapeutic Effects of Myelostem 50mg Injection
Myelostem 50mg injection is an alkylating agent. It exerts its cytotoxic action primarily due to the cross-linking of strands of DNA and RNA, as well as the inhibition of protein synthesis. It works by stopping or slowing the growth of cancer cells in your body.
Interaction of Myelostem 50mg Injection with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications interact with myelostem 50mg injection and reduce its effectiveness by causing undesirable side effects.
More Information about Myelostem 50mg Injection
- Store in a refrigerator, 2° to 8°C
- Protect the medicine from light and excessive moisture.
- Keep the medicine out of reach of children and pets
- If you forgot to take the tablet, simply take your next dose at the scheduled time. Do not take a double dose to make up for a forgotten dose.
How to consume Myelostem 50mg Injection
Your doctor will decide the dose and duration of myelostem 50mg injection based on the disease condition and other factors. Always take this medicine as prescribed by your doctor. Take the tablet at the same time, with or without food. Do not break, chew, crush, or break the tablet. Swallow the whole tablet with water.
Safety Advice for Myelostem 50mg Injection
Breast Feeding
Breastfeeding is not recommended in patients taking myelostem 50mg injection because the medicine passes into the breast milk in small amounts and may harm your baby. Do not breastfeed during the treatment.
Alcohol
It is not known whether it is safe to consume alcohol with myelostem 50mg injection. Please consult your doctor.
Liver
There is limited information available on the use of myelostem 50mg injection in patients with liver disease. Please consult your doctor if you have any liver diseases.
Lungs
It is unknown whether myelostem 50mg injection can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
Driving
It is not known whether myelostem 50mg injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Pregnancy
Do not take myelostem 50mg injection if you are pregnant because this may harm the unborn baby. Inform your physician if you are pregnant, suspecting pregnancy, or planning to get pregnant during the treatment. Use effective contraception during the treatment.
Side Effects of Myelostem 50mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
- Cardiac arrest
- Liver inflammation
- Hypersensitivity skin reactions
- Acute renal failure
- Lung inflammation
Common
- Decreased blood cell count
- Nausea
- Vomiting
- Diarrhea
- Mouth ulcers
- Hair loss
Word of Advice
Myelostem 50mg injection may cause changes in your blood levels. Your doctor may advise you to take certain blood tests during the treatment to monitor any unwanted side effects. Do not take an extra dose to make up for a missed dose. This medicine could cause infertility. Talk with your doctor before using this medicine if you are planning for pregnancy. This medicine may cause you to bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury.
FAQs about Myelostem 50mg Injection
Q1.
Can a patient with kidney problems take myelostem 50mg injection?
Myelostem 50mg injection should be cautiously taken if you have any kidney problems. Dose adjustments are necessary for patients with kidney diseases. Inform your doctor if you are on dialysis and have any kidney disorders.
Q2.
Does myelostem 50mg injection weaken the immune system?
Myelostem 50mg injection can suppress your immune system and increase your chances of getting infections. Take precautions to prevent illness and injury.
Q3.
What if I overdose or take two doses of myelostem 50mg injection?
If you unknowingly took two doses of myelostem 50mg injection, immediately inform your healthcare professional and seek medical advice.
Q4.
Does myelostem 50mg injection cause hair loss?
Thinning or loss of your hair will usually start within two to four weeks of your first dose of myelostem 50mg injection. You may also have thinning or loss of eyelashes, eyebrows, and other body hair. Consult your doctor if you have excessive hair loss.
Q5.
Is it safe to use myelostem 50mg injection while pregnant?
Do not take myelostem 50mg injection if you are pregnant because this may harm the unborn baby. Inform your physician if you are pregnant, suspecting pregnancy, or planning to get pregnant during the treatment. Use effective contraception during the treatment.
Fact Box of Myelostem 50mg Injection
Molecule name: Melphalan | Therapeutic class: Antineoplastics |
Pharmacological class: Alkylating agents | Indications: 1.Multiple myeloma 2. Advanced breast cancer 3. Advanced ovarian cancer 4. Polycythemia vera |
References
- Melphalan- Summary of Product Characteristics (SmPC) - (EMC) www.medicines.org.uk. [revised on 2022] [cited 2023 Apr 7]. Available from: https://www.medicines.org.uk/emc/product/3806/smpc
- ALKERAN ® 2 - myelostem 50mg injection [revised on 2021] [cited 2023 Apr 7]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2003/14691slr024_alkeran_lbl.pdf
- KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 860.
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Author Details
Written By
Dr. Archana Gupta
BDS
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 31 Mar 2026 | 09:30 AM (IST)
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