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Myelostop 500 Capsule
Last updated on 31 Mar 2026 | 09:29 AM (IST)
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Introduction
Myelostop 500 Capsule is an anticancer medication containing the active ingredient as Hydroxyurea. It is used to treat chronic myeloid leukemia (cancer of white blood cells) and polycythemia vera (cancer of red blood cells). The benefits of this medication include treating cancer by slowing down the growth and division of cancer cells and treating sickle cell anemia by reducing the frequency and severity of painful episodes and preventing organ damage. It is used to treat cervical, ovarian, and melanoma (skin cancer) and head and neck cancer. Cancer is a disorder in which cells multiply in an uncontrolled and abnormal manner.
It is used to treat sickle cell anemia (an inherited blood disease in which healthy red blood cells are insufficient). This medication may be used to treat other conditions not mentioned here. You need to talk to your physician if you have any blood disorders, severe anemia, kidney disorders, liver disorders, gout, leg ulcers, folic acid deficiency, or have an intolerance to some sugars before taking Myelostop 500 Capsules.
Uses
Myelostop 500 Capsule is approved for the following conditions:
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Ovarian cancer
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Polycythemia vera
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Chronic myeloid leukemia
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Cervical cancer
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Head and neck cancer
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Sickle cell anemia
How Myelostop 500 Capsule works
In cancer, Myelostop 500 Capsule works by slowing down the growth and division of cancer cells, which can help to shrink tumors and prevent the spread of cancer to other parts of the body. This can lead to a reduction in the size and number of tumors, which may improve symptoms and increase survival rates. In sickle cell anemia, this medication works by increasing the production of fetal hemoglobin, which can help to prevent the abnormal shaping of red blood cells. This can reduce the frequency and severity of painful episodes, prevent damage to organs, and improve the overall quality of life. It also reduces the need for blood transfusions and hospitalizations. It prevents complications such as stroke, acute chest syndrome, and pulmonary hypertension.
Interaction of Myelostop 500 Capsule with other medicines
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Myelostop 500 Capsule and reduce effectiveness by causing undesirable side effects.
Storage conditions
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Myelostop 500 Capsule should be stored at room temperature between 68°F to 77°F (20°C to 25°C).
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Keep in the original package.
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Keep away from light, moisture, and heat.
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Keep it away from children and pets.
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Shake well before use
How to take Myelostop 500 Capsule
To consume Myelostop 500 Capsule, shake the bottle well before each use to ensure the medicine is properly mixed. Measure the prescribed dose using the provided measuring cup or spoon. Take it by mouth, preferably after meals to reduce the risk of stomach upset. Follow your doctor’s instructions carefully regarding dosage and duration. Do not exceed the recommended dose, and consult your doctor if you miss a dose or experience any side effects.
Safety Advices
Pregnancy
Myelostop 500 Capsule is not safe for use during pregnancy because it can harm to developing baby. You need to tell your physician if you are pregnant or planning to get pregnant before taking this medicine.
Breast Feeding
It is not safe to take Myelostop 500 Capsules while breastfeeding. It has been shown to pass into breast milk, and its affects the nursing infant. Because of this, women who are taking this medication should avoid breastfeeding.
Lungs
Myelostop 500 Capsules can cause lung toxicity, although this is a rare side effect. If you have pre-existing lung problems or a history of radiation therapy to the lungs, you should tell your healthcare provider before taking this medication.
Liver
Myelostop 500 Capsule can potentially cause liver damage, although this is also a rare side effect. People who have pre-existing liver disease are at a higher risk. You need to tell your physician if you have any liver disorders before taking it, as this medication should be used with caution in liver disorder patients.
Alcohol
Alcohol consumption can negatively affect the immune system and may interfere with the effectiveness of cancer therapies. So it is recommended to avoid taking alcohol while taking Myelostop 500 Capsule.
Driving
Patients receiving Myelostop 500 Capsule should be advised to avoid driving or operating machinery if they experience side effects such as fatigue, dizziness, or blurred vision, impairing a patient's ability to drive or operate machinery safely.
Side Effects
Like all medications, Myelostop 500 Capsule can cause side effects, although not everyone who takes it will experience them.
Serious
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Bone marrow suppression (decreased blood cell count)
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Skin reactions (rash, itching, and skin ulcers)
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Stevens-Johnson syndrome (life-threatening skin reaction)
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Tumor lysis syndrome (occur when large numbers of cancer cells are killed rapidly)
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Liver damage (jaundice, dark urine, pale stools, nausea, vomiting, and abdominal pain)
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Lung toxicity (shortness of breath, cough, fever, and chest pain)
Common
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Nausea
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Vomiting
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Diarrhea
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Loss of appetite
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Mouth sores
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Headache
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Dizziness
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Fatigue
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Skin darkening
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Hair loss or thinning
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Nail changes
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Constipation
Expert Tips
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Follow your healthcare provider’s instructions carefully when taking Myelostop 500 Capsule.
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Report any side effects or changes in your health to your doctor promptly.
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Women taking contraceptives should inform their doctor before starting treatment.
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If you could become pregnant, use effective birth control during treatment and for at least three months after the last dose.
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Inform your doctor if you have liver, lung, or kidney disease before starting the medication.
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Use sun protection while taking this medication.
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During cancer treatment, follow a diet rich in fruits, vegetables, whole grains, and lean proteins.
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Limit processed and high-fat foods while on treatment.
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Drink plenty of water and stay well-hydrated.
FAQs
Q1.
Does Myelostop 500 Capsule interact with other medications?
Yes, Myelostop 500 Capsule can interact with other medications, including blood thinners, vaccines, and certain antibiotics.
Q2.
Can Myelostop 500 Capsule cause skin cancer?
There is a small risk that long-term use of Myelostop 500 Capsules may increase the risk of developing skin cancer, particularly squamous cell carcinoma. People taking this medication should avoid prolonged exposure to sunlight and use protective clothing and sunscreen to reduce their risk of developing skin cancer.
Q3.
Can Myelostop 500 Capsule be used in children?
Yes, Myelostop 500 Capsule can be used in children with certain medical conditions, such as sickle cell disease and certain types of leukemia. However, the dosage and administration may differ from that used in adults, and a healthcare provider should closely monitor the use of this medication in children.
Q4.
Can Myelostop 500 Capsule be used to treat COVID-19?
There is currently no evidence to support the use of Myelostop 500 Capsule in the treatment of COVID-19. It is used primarily to treat certain types of cancer and blood disorders.
Q5.
Can Myelostop 500 Capsule be used as a preventive measure for sickle cell disease complications?
Yes, Myelostop 500 Capsule is sometimes used as a preventive measure to reduce the frequency and severity of complications in people with sickle cell disease. It can help increase fetal hemoglobin production, preventing sickle cell crises and other complications.
Fact Box
|
Molecule name: |
Hydroxyurea |
|
Therapeutic class |
Anticancer |
|
Pharmacological class |
Antimetabolite |
|
Indications |
1. Ovarian cancer 2. Polycythemia vera 3.Chronic myeloid leukemia 4.Cervical cancer 5. Head and neck cancer 6. Sickle cell anemia |
References
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Bristol-Myers Squibb Pharmaceuticals Unlimited Company, Electronic medicines compendium (EMC), [Revised on August 2021] [ Accessed on 17 April 2023], https://www.medicines.org.uk/emc/files/pil.271.pdf
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Bristol-Myers Squibb Company, US Food and Drug Administration, [Revised on March 2016] [ Accessed on 17th April 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/016295Orig1s047,s048Lbl.pdf
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Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Cytotoxic agents, 12th edition, 2011, 1721.
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KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 868.
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Rohit Kumar Agarwal et al; Hydroxyurea in Sickle Cell Disease: Drug Review; Indian Journal of Hematology & Blood Transfusion; Published on June 2014; Accessed on 17 April 2023; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022916/#__ffn_sectitle
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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Author Details

Written By
Dr. Vikas B S
Pharm D

Reviewed By
Dr. Abhishaanth Prabu
MBBS
Last updated : 31 Mar 2026 | 09:29 AM (IST)

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