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NAVELBINE 10MG INJECTION_1
NAVELBINE 10MG INJECTION_2
NAVELBINE 10MG INJECTION_1
20% Off

NAVELBINE 10MG INJECTION

Prescription Required

cold-chain

Salt Composition : Vinorelbine

Manufacturer : ABBOTT

Origin of Medicine : India

MRP: ‚āĻ4250
Price : ‚āĻ3391
You Save : ‚āĻ859 (20%)

1 Vial(s) Of 1ml

Prepaid Only. Non-Returnable


Introduction to Navelbine 10mg Injection

Navelbine 10mg Injection is a chemotherapy medication containing the active constituent Vinorelbine. It belongs to the group of medications known as vinca alkaloids. It is indicated to treat non-small cell lung cancer and breast cancer. Cancer is a disorder in which cells multiply in an uncontrolled and abnormal manner. This medication is not recommended for adolescents and children under 18 years of age. 

The common side effects that are likely to associate with Navelbine 10mg Injection are nausea, vomiting, low blood cell counts, tiredness, weakness, hair loss, pain in the jaws, joints, and muscles, diarrhea, swelling or sores in the throat or mouth, and injection site reactions (redness, burning pain, vein discoloration). Inform your physician if these side effects disturb or persist in you.  

Report to your doctor if you are allergic to Navelbine 10mg Injection and its ingredients. While taking this Injection, Inform your physician if you have any signs or symptoms of infection (cough, fever, chills, or joint pain), severe chest pain, history of heart attack, or liver disorders. Before and during treatment with this medication, your physician will check the blood cell count. Use effective birth control during the treatment and at least three months after the final dose. Inform your physician about all your medicines, including herbal medicines and supplements. Many vaccines (live attenuated vaccines) are not recommended during this treatment. Consult your healthcare professional if you have recently received any vaccines or require any.


Uses of Navelbine 10mg Injection

  • Non-small cell lung cancer (NSCLC)
  • Breast cancer

Therapeutic Effects of Navelbine 10mg Injection

Navelbine 10mg Injection works by inhibiting the microtubule structures within the cell. Microtubule structures help cancer cells to divide and multiply. Inhibition of these structures slows the growth and multiplication of cancer cells.


Interaction of Navelbine 10mg Injection with other drugs

Inform your doctor about any prescribed medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products that you are taking or have taken before the treatment. Certain medications tends to interact with Navelbine 10mg  Injection and can cause undesirable side effects. 


More Information about Navelbine 10mg Injection

  • Keep Navelbine¬†10mg¬†Injection out of sight and reach of children.
  • Store in a refrigerator (2¬įC to 8¬įC).

How to consume Navelbine 10mg Injection

Navelbine 10mg Injection is administered into a vein by your healthcare provider. The dose and duration are decided by your physician, depending on the condition.  Do not self-administer. 


Safety Advices for Navelbine 10mg Injection

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Pregnancy

  

Navelbine 10mg Injection is unsafe to use during pregnancy as it may harm the unborn baby.

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Breast Feeding

  

It is not recommended for breastfeeding while taking Navelbine 10mg  Injection. 

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Lungs

  

It is unknown whether Navelbine 10mg Injection can be administered to lung failure patients. Please consult your physician, if you have any lung problems. 

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Liver

  

Inform your physician if you have any liver disorders before taking Navelbine 10mg Injection, as this medication should be used with caution in liver disease patients.

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Alcohol

  

It is unknown whether it is safe to consume alcohol with Navelbine 10mg  Injection. Consult your doctor for advice. 

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Driving

  

Navelbine 10mg Injection may cause side effects that could impair your driving ability. Avoid driving if you are unwell.


Side Effects of Navelbine 10mg Injection

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. 

Serious

  • Severe allergic reactions (rash, difficulty in breathing, swelling of eyelids, lips, face, or throat)
  • Severe chest pain
  • Severe low blood pressure (severe dizziness, lightheadedness when you stand up)
  • Severe constipation with abdominal pain
  • Major infection (cough, fever, chills)

Common

  • Nausea, vomiting
  • Low blood cell counts, weakness
  • Hair loss
  • Swelling or sores in the throat or mouth
  • Injection site reactions (redness, burning pain, vein discoloration)
  • Pain in the jaws, joints, and muscles
  • Tiredness
  • Diarrhea

Word of Advice

It is suggested that women should use effective birth control for at least three months before starting and during treatment with Navelbine 10mg Injection. Male patients are advised to use effective contraception during therapy and three months after treatment to avoid fathering children.  Before receiving this Injection treatment, male patients should get advice on sperm conservation. Your doctor may take regular blood tests to monitor your blood cell count, platelet count, and liver function.


FAQs

Q 1. What is Navelbine 10mg Injection used for?

Navelbine 10mg Injection treats nonsmall cell lung cancer (NSCLC) and breast cancer. It belongs to the group of medications called Vinca alkaloids.

Q 2. Can I take vaccinations while taking Navelbine 10mg Injection?

No, you should not vaccinate with "live" or "attenuated" vaccinations. Hence, without consulting your healthcare provider, Navelbine 10mg Injection should not be taken with any vaccinations.

Q 3. Can children use Navelbine 10mg Injection?

No, Navelbine 10mg Injection is not recommended for usage in children

Q 4. Is it safe to become a father while taking Navelbine 10mg Injection?

It is unsafe to become a father during and three months after treatment. Hence, effective contraceptives must be used, and get advice on sperm conservation before Vinoreline treatment because it may alter male fertility.

Q 5. Who is contraindicated to taking Navelbine 10mg Injection?

Patients with severe kidney problems, low blood cells, low platelet, severe infection, and pregnant and breastfeeding mothers should not use this Injection. It is also not recommended for patients allergic to Navelbine 10mg Injection and its ingredients.

Q 6. I am pregnant. Can I take Navelbine 10mg Injection?

If you are pregnant, avoid taking Navelbine 10mg Injection as it can cause harmful effects on the unborn baby. Females should follow effective birth control methods during treatment and at least three months after the treatment.


Fact Box of Navelbine 10mg Injection

Molecule name: Vinorelbine

Therapeutic class: Antineoplastics

Pharmacological class: Vinca alkaloids

Indications: 

1. Non-small cell lung cancer (NSCLC)

2. breast cancer


References

  1. Pierre Fabre Limited, Electronic medicines compendium (EMC), [Revised on Nov 2022] [ Accessed on 1st Dec 2022], https://www.medicines.org.uk/emc/files/pil.3912.pdf
  2. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Cytotoxic agents, 12th edition, 2011, 1706.
  3. KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 865.
  4. Pierre Fabre Medicament, US Food and Drug administration, [Revised on Jan 2022] [ Accessed on 1st Dec 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/020388s037lbl.pdf
  5. Anna Capasso; Vinorelbine in Cancer therapy; Cancer Drug Targets; Published on July 2012; Accessed on 01/12/2022; https://pubmed.ncbi.nlm.nih.gov/22594474/
  6. Ying-Chun Xu et al; A systematic review of vinorelbine for the treatment of breast cancer; The Breast Journal; Published on April 2013; Accessed on 01/12/2022; https://pubmed.ncbi.nlm.nih.gov/23320984/

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