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Navelbine 50mg Injection
Salt Composition : Vinorelbine
Manufacturer : ABBOTT
Origin of Medicine : India
1 Vial(s) Of 5ml
Introduction to Navelbine 50mg Injection
Navelbine 50mg Injection is a chemotherapy medication containing the active constituent Vinorelbine. It belongs to the group of medications known as vinca alkaloids. It is indicated to treat non-small cell lung cancer and breast cancer. Cancer is a disorder in which cells multiply in an uncontrolled and abnormal manner. This medication is not recommended for adolescents and children under 18 years of age.
The common side effects that are likely to associate with Navelbine 50mg Injection are nausea, vomiting, low blood cell counts, tiredness, weakness, hair loss, pain in the jaws, joints, and muscles, diarrhea, swelling or sores in the throat or mouth, and injection site reactions (redness, burning pain, vein discoloration). Inform your physician if these side effects disturb or persist in you.
Report to your doctor if you are allergic to Navelbine 50mg Injection and its ingredients. While taking this Injection, Inform your physician if you have any signs or symptoms of infection (cough, fever, chills, or joint pain), severe chest pain, history of heart attack, or liver disorders. Before and during treatment with this medication, your physician will check the blood cell count. Use effective birth control during the treatment and at least three months after the final dose. Inform your physician about all your medicines, including herbal medicines and supplements. Many vaccines (live attenuated vaccines) are not recommended during this treatment. Consult your healthcare professional if you have recently received any vaccines or require any.
Uses of Navelbine 50mg Injection
- Non-small cell lung cancer (NSCLC)
- Breast cancer
Therapeutic Effects of Navelbine 50mg Injection
Navelbine 50mg Injection works by inhibiting the microtubule structures within the cell. Microtubule structures help cancer cells to divide and multiply. Inhibition of these structures slows the growth and multiplication of cancer cells.
Interaction of Navelbine 50mg Injection with other drugs
Inform your doctor about any prescribed medications, over-the-counter medications, nutritional or vitamin supplements and herbal products that you are taking or have taken before the treatment. Certain medications tends to interact with Navelbine 50mg Injection and can cause undesirable side effects.
More Information about Navelbine 50mg Injection
- Keep Navelbine 50mg Injection out of sight and reach of children.
- Store in a refrigerator (2°C to 8°C).
How to consume Navelbine 50mg Injection
Navelbine 50mg Injection is administered into a vein by your healthcare provider. The dose and duration are decided by your physician, depending on the condition. Do not self-administer.
Safety Advices for Navelbine 50mg Injection
Navelbine 50mg Injection is unsafe to use during pregnancy as it may harm the unborn baby.
It is not recommended for breastfeeding while taking Navelbine 50mg Injection.
It is unknown whether Navelbine 50mg Injection can be administered to lung failure patients. Please consult your physician, if you have any lung problems.
Inform your physician if you have any liver disorders before taking Navelbine 50mg Injection, as this medication should be used with caution in liver disease patients.
It is unknown whether it is safe to consume alcohol with Navelbine 50mg Injection. Consult your doctor for advice.
Navelbine 50mg Injection may cause side effects that could impair your driving ability. Avoid driving if you are unwell.
Side Effects of Navelbine 50mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
- Severe allergic reactions (rash, difficulty in breathing, swelling of eyelids, lips, face, or throat)
- Severe chest pain
- Severe low blood pressure (severe dizziness, lightheadedness when you stand up)
- Severe constipation with abdominal pain
- Major infection (cough, fever, chills)
- Nausea, vomiting
- Low blood cell counts, weakness
- Hair loss
- Swelling or sores in the throat or mouth
- Injection site reactions (redness, burning pain, vein discoloration)
- Pain in the jaws, joints, and muscles
Word of Advice
It is suggested that women should use effective birth control for at least three months before starting and during treatment with Navelbine 50mg Injection. Male patients are advised to use effective contraception during therapy and three months after treatment to avoid fathering children. Before receiving this Injection treatment, male patients should get advice on sperm conservation. Your doctor may take regular blood tests to monitor your blood cell count, platelet count, and liver function.
Q 1. What is Navelbine 50mg Injection used for?
Navelbine 50mg Injection treats nonsmall cell lung cancer (NSCLC) and breast cancer. It belongs to the group of medications called Vinca alkaloids.
Q 2. Can I take vaccinations while taking Navelbine 50mg Injection?
No, you should not vaccinate with "live" or "attenuated" vaccinations. Hence, without consulting your healthcare provider, Navelbine 50mg Injection should not be taken with any vaccinations.
Q 3. Can children use Navelbine 50mg Injection?
No, Navelbine 50mg Injection is not recommended for usage in children
Q 4. Is it safe to become a father while taking Navelbine 50mg Injection?
It is unsafe to become a father during and three months after treatment. Hence, effective contraceptives must be used, and get advice on sperm conservation before Vinoreline treatment because it may alter male fertility.
Q 5. Who is contraindicated to taking Navelbine 50mg Injection?
Patients with severe kidney problems, low blood cells, low platelet, severe infection, and pregnant and breastfeeding mothers should not use this Injection. It is also not recommended for patients allergic to Navelbine 50mg Injection and its ingredients.
Q 6. I am pregnant. Can I take Navelbine 50mg Injection?
If you are pregnant, avoid taking Navelbine 50mg Injection as it can cause harmful effects on the unborn baby. Females should follow effective birth control methods during treatment and at least three months after the treatment.
Fact Box of Navelbine 50mg Injection
Molecule name: Vinorelbine
Therapeutic class: Antineoplastics
Pharmacological class: Vinca alkaloids
1. Non-small cell lung cancer (NSCLC)
2. breast cancer
- Pierre Fabre Limited, Electronic medicines compendium (EMC), [Revised on Nov 2022] [ Accessed on 1st Dec 2022], https://www.medicines.org.uk/emc/files/pil.3912.pdf
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Cytotoxic agents, 12th edition, 2011, 1706.
- KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 865.
- Pierre Fabre Medicament, US Food and Drug administration, [Revised on Jan 2022] [ Accessed on 1st Dec 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/020388s037lbl.pdf
- Anna Capasso; Vinorelbine in Cancer therapy; Cancer Drug Targets; Published on July 2012; Accessed on 01/12/2022; https://pubmed.ncbi.nlm.nih.gov/22594474/
- Ying-Chun Xu et al; A systematic review of vinorelbine for the treatment of breast cancer; The Breast Journal; Published on April 2013; Accessed on 01/12/2022; https://pubmed.ncbi.nlm.nih.gov/23320984/
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