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Nefdapa 10mg Tablet
Last updated on 31 Mar 2026 | 09:30 AM (IST)
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Introduction to Nefdapa 10mg Tablet
Nefdapa 10mg Tablet is an antidiabetic drug in the category of sodium-glucose cotransport-2 (SGLT-2) inhibitors, containing the active ingredient Dapagliflozin. It mainly treats type 2 diabetes mellitus in patients above 18 years and older. Diabetes mellitus is a chronic metabolic disease characterized by increased blood sugar levels (hyperglycemia). This drug is also approved for treating heart failure with reduced ejection fraction (HFrEF) in adults. It helps to improve symptoms and reduce the risk of hospitalization for heart failure.
This drug mainly helps to control high blood glucose (sugar) levels in individuals with type 2 diabetes. It is always taken in combination with diet and exercise. Your doctor may prescribe this medicine with other antidiabetic medications when your blood sugar is high and uncontrolled. Do not take this medicine if you are allergic to Nefdapa 10mg Tablet or any of its other ingredients. Inform your physician if you get urinary tract infections because this medicine may cause UTI. This medicine is not recommended for children and adolescents under 18.
Your doctor will check for kidney function at least once every year or more frequently while you are taking this medicine. If you experience nausea, vomiting, fever, or cannot eat or drink while taking Nefdapa 10mg Tablet, it is important to inform your doctor. These conditions can lead to dehydration, and your doctor may advise temporarily discontinuing the medication until you have recovered. When taking this drug, diabetic ketoacidosis (DKA) can occur even if blood sugar levels are normal. If you suspect you have symptoms of DKA, it is necessary to contact your doctor or go to the nearest hospital without delay.
Uses of Nefdapa 10mg Tablet
- Type 2 diabetes mellitus
- Heart Failure
Therapeutic Effects of Nefdapa 10mg Tablet
Nefdapa 10mg Tablet reduces glucose reabsorption and lowers the renal threshold for glucose. It mainly works by removing excess sugar from your body via your urine and lowering the sugar in your blood.
Interaction of Nefdapa 10mg Tablet with other drugs
Inform your physician about all your medicines, including prescription, over-the-counter, nutritional supplements, and herbal products. Certain medications interact with Nefdapa 10mg Tablet and reduce its effectiveness by causing undesirable side effects.
More Information about Nefdapa 10mg Tablet
- Store Nefdapa 10mg Tablet in a room temperature (20°C to 25°C)
- Keep the medicine out of reach of children and pets
How to consume Nefdapa 10mg Tablet
Take the Nefdapa 10mg Tablet as advised by your physician. Do not chew or break the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.
Safety Advice for Nefdapa 10mg Tablet
Breast Feeding
Breastfeeding is not recommended in patients taking Nefdapa 10mg Tablet because it is unknown whether the medicine passes into the breast milk and may harm your baby.
Alcohol
It is unsafe to consume alcohol with Nefdapa 10mg Tablet. Inform your doctor about your drinking habits.
Liver
Nefdapa 10mg Tablet is safe to use in patients with liver problems. Inform your physician if you have liver diseases before initiating the treatment.
Lungs
It is unknown whether Nefdapa 10mg Tablet is safe for lung disease patients. Inform your physician if you have any lung diseases before initiating the therapy.
Driving
Nefdapa 10mg Tablet is not known to cause drowsiness or impair driving ability, so they are generally considered safe for use while driving or operating machinery.
Pregnancy
Do not take Nefdapa 10mg Tablet if you are pregnant because this may harm the unborn baby. Inform your physician if you are pregnant, suspecting, or planning to get pregnant during the treatment.
Side Effects of Nefdapa 10mg Tablet
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious:
- Diabetic ketoacidosis
- Urinary tract infection
- Angioedema
- Necrotizing fasciitis of the perineum
Common:
- Genital infection (thrush) of your penis or vagina (signs may include irritation, itching, unusual discharge, or odor)
- Back pain
- Dizziness
- Rash
- Urgency in urination
- Excessive thirst
Word of Advice
Nefdapa 10mg Tablet can increase urination, possibly leading to dehydration if not compensated for by adequate fluid intake. Drink plenty of water often to stay well hydrated. This drug causes genital yeast infections in both males and females. Practice good hygiene, including regular washing and cleaning of the genital area, to reduce the risk of infections. Limit the intake of sugary foods, processed snacks, and high-fat meals.
FAQs about Nefdapa 10mg Tablet
Q1.
Can Nefdapa 10mg Tablet cause weight loss?
Yes, Nefdapa 10mg Tablet can cause weight loss in some individuals. One of the effects of Nefdapa 10mg Tablet is the excretion of excess glucose in the urine. It leads to a loss of calories and can contribute to weight reduction.
Q2.
How does Nefdapa 10mg Tablet work?
Nefdapa 10mg Tablet reduces glucose reabsorption and lowers the renal threshold for glucose. It works by removing excess glucose from your body via your urine and lowering the sugar in your blood.
Q3.
Is Nefdapa 10mg Tablet used for type 1 diabetes?
Nefdapa 10mg Tablet is not approved for use in type 1 diabetes. It is specifically indicated for the treatment of type 2 diabetes mellitus.
Q4.
Can you take Nefdapa 10mg Tablet twice a day?
Your doctor will decide the medicine's dose, strength, and frequency based on your blood sugar levels and other factors. Take Nefdapa 10mg Tablet as prescribed by your doctor.
Q5.
How does Nefdapa 10mg Tablet help control blood sugar levels?
Nefdapa 10mg Tablet works by inhibiting glucose reabsorption in the kidneys, increasing glucose excretion in the urine, and lowering blood sugar levels. It helps to improve glycemic control in people with type 2 diabetes.
Q6.
Can Nefdapa 10mg Tablet be used in people with kidney problems?
Nefdapa 10mg Tablet should be used with caution in individuals with kidney problems. The dose adjustments can be made based on kidney function. It is important to inform your physician about any existing kidney issues or changes in kidney function before taking this drug.
Fact Box of Nefdapa 10mg Tablet
Molecule name: Dapagliflozin | Therapeutic class: Antidiabetic agent
|
Pharmacological class: Sodium-glucose cotransport-2 (SGLT-2) inhibitor | Indications: 1. Type 2 diabetes mellitus 2. Heart Failure |
References
- AstraZeneca UK Limited, Electronic medicines compendium (EMC), [Revised on Nov 2022], [Accessed on 15th June 2023] https://www.medicines.org.uk/emc/files/pil.7607.pdf
- Dapagliflozin- food and drug administration (FDA). [Revised on May 2020], [Accessed on 15th June 2023] https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/202293s020lbl.pdf
- AstraZeneca AB, European Medicines Agency (EMA), [Accessed on 15th June 2023], https://www.ema.europa.eu/en/documents/product-information/forxiga-epar-product-information_en.pdf
- KD Tripathi, Essentials of Medical Pharmacology, Hormones and related drugs, 7th edition, 2013, 278.
- Bertram.G.Katzung, Basic and Clinical Pharmacology, Pancreatic Hormones & Antidiabetic Drugs, 14th edition, 2017, 763
Disclaimer
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Author Details
Written By
Sakshi Anil More
B. Pharm
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 31 Mar 2026 | 09:30 AM (IST)
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