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Nuphos 500mg Injection
Prescription Required
Salt Composition : Cyclophosphamide
Manufacturer : ZEE LABORATORIES LTD
Origin of Medicine : India
1 Vial(s)
Introduction to Nuphos 500mg Injection
Nuphos 500mg Injection is an anticancer drug used in the treatment of various malignancies (abnormal production of cells is called cancer if they spread, those are called malignancies). It contains cyclophosphamide, which cross-links the DNA and damages its ultrastructure resulting in cancer cell death. Nuphos 500mg Injection can be used in the treatment of malignant lymphomas (cancers that start from the lymphatic system of the body- vessels, fluid, and lymphoid tissue) such as Hodgkin’s disease, lymphocytic lymphoma, mixed-cell type lymphoma, leukemias, neuroblastoma, ovarian cancer, retinoblastoma and breast carcinoma. It can also be used in the treatment of Minimal Change Nephrotic syndrome in pediatric patients (kidney disease in which large quantities of protein are lost in urine).
Nuphos 500mg Injection is contraindicated in pregnancy, patients with acute infections, urinary tract infections, urinary outflow obstruction, and bone marrow disorders. Treatment with this medicine may lead to immune suppression, bone marrow failure, cardiotoxicity, renal toxicity, pulmonary toxicity, and secondary malignancies, Inform your doctor if you have pre-existing kidney disease, immune conditions, cardiac disorders, or liver diseases.
Uses of Nuphos 500mg Injection
- Malignant lymphomas
- Leukemias
- Retinoblastoma
- Carcinoma of breast
- Ovarian cancer
- Mycosis fungoides
- Minimal Change Nephrotic Syndrome in Pediatric Patients
Therapeutic Effects of Nuphos 500mg Injection
It is believed to work by cross-linking of strands of DNA in the tumor cells and damages the tumor cells.
Interaction of Nuphos 500mg Injection with other drugs
Inform your doctor about any prescribed medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products that you are taking or have taken before the treatment. Certain medications may interact with Nuphos 500mg Injection and cause potential side effects.
More Information about Nuphos 500mg Injection
- Store it below 25 °C
- Keep away from pets and children
- Store it properly away from light and moisture
How to consume Nuphos 500mg Injection
It will be administered intravenously by physicians who are experienced in cancer chemotherapy.
Safety Advices for Nuphos 500mg Injection
Pregnancy
Nuphos 500mg Injection can cause fetal harm when administered to the pregnant woman. Inform your physician if you are pregnant or planning to get pregnant before taking this medication. Your physician will instruct you to take when it is necessary.
Breast Feeding
Avoid this medication if you are breastfeeding. Consult your doctor for potential risks and benefits.
Lungs
Inform your doctor if you have any lungs disorders.
Liver
Inform your doctor if you have any liver disorders.
Alcohol
It is not safe to consume alcohol while undergoing this therapy.
Driving
The patient undergoing treatment with this medicine may have dizziness, blurred vision. Consult your doctor before driving and handling heavy machines.
Side Effects of Nuphos 500mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Serious:
- Infections
- Immune suppression
- Blood disorders
- Allergic reactions
- Abnormal liver function
- Inflammation of the bladder
- Kidney diseases
- blood in urine
- sterility
- impaired wound healing
Common:
- Nausea, vomiting
- Low white blood cell count
- Diarrhea
- Hair loss
- Fever
- Weakness
- Inflammation
- Dizziness
- Blurred vision
- amenorrhea
Word of Advice
Inform the doctor if the patient has any kidney, liver, heart problems and medication taken for different medical conditions. It causes immune suppression and hence inform the doctor if there are any immune problems. Avoid this medication if the patient is pregnant or breastfeeding mother. The patient undergoing treatment with this medicine may have dizziness, blurred vision. Consult your doctor before driving and handling heavy machines.
FAQs
Q 1. Is Nuphos 500mg Injection chemotherapy medication?
Yes, Nuphos 500mg Injection is a chemotherapy medicine and it works by killing cancer cells. It prevents the spreading of cancer cells to different parts.
Q 2. Can Nuphos 500mg Injection cause weight loss?
Yes, Nuphos 500mg Injection causes weight loss due to reduced appetite and consult the doctor if there is excessive weight loss.
Fact Box of Nuphos 500mg Injection
Molecule name | Nuphos 500mg Injection |
Therapeutic class | Alkylating agent |
Pharmacological class | Antirheumatic drugs |
Indications | Malignant lymphomas, Leukemias, Retinoblastoma, Carcinoma of breast, Ovarian cancer, Mycosis fungoides, Minimal Change Nephrotic Syndrome in Pediatric Patients |
References
- KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 860.
- Baxter, Electronic medicines compendium (emc), [ Revised on June 2016] [ Accessed on 8th April 2021], https://www.medicines.org.uk/emc/product/1815/smpc
- Baxter, US Food and Drug Administration, [ Revised on May 2013] [ Accessed on 7th April 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/012141s090,012142s112lbl.pdf
Disclaimer
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